Zobrazeno 1 - 8
of 8
pro vyhledávání: '"N J L, Gittoes"'
Autor:
N. J. L. Gittoes, Christopher McCabe
Publikováno v:
Journal of Endocrinology. 162:163-166
The pathogenesis of sporadic pituitary tumours remains elusive. Recently, a new candidate gene has been described which is able to induce pituitary cell transformation, and the expression of which appears to be strongly correlated with pituitary tumo
Autor:
N. J. L. Gittoes
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 82:1960-1967
Autor:
S. R. J. Maxwell, N. J. L. Gittoes
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 19:285-293
SUMMARY Diabetic nephropathy is a common cause of end stage renal failure. Patients ultimately require dialysis or transplantation and endure a poor quality of life in association with increased mortality. Due to the quantitative significance of this
Autor:
C J, McCabe, J S, Khaira, K, Boelaert, A P, Heaney, L A, Tannahill, S, Hussain, R, Mitchell, J, Olliff, M C, Sheppard, J A, Franklyn, N J L, Gittoes
Publikováno v:
Clinical endocrinology. 58(2)
Pituitary tumour transforming gene (PTTG) encodes a multifunctional protein that is implicated in initiating and perpetuating pituitary adenoma growth. PTTG appears to have key regulatory functions in determining control of many fundamental cellular
Autor:
L A, Tannahill, T J, Visser, C J, McCabe, S, Kachilele, K, Boelaert, M C, Sheppard, J A, Franklyn, N J L, Gittoes
Publikováno v:
Clinical endocrinology. 56(6)
Thyroid hormones (THs) perform essential roles in pituitary function. They regulate anterior pituitary hormone secretion and are also key determinants of pituitary cell proliferation and differentiation. The critical role of deiodinase enzymes, which
Autor:
Jayne A. Franklyn, Patrick J. Butler, Charles M. Bishop, Christopher McCabe, N. J. L. Gittoes
Publikováno v:
The Journal of endocrinology. 165(3)
Skeletal muscles are important target tissues for thyroid hormone action. The present study examines the influence of thyroid status on muscle growth and tissue-specific expression of thyroid receptor (TR) mRNA isoforms in a commercial strain of the
Autor:
N. J. L. Gittoes
Publikováno v:
The Journal of endocrinology. 157(2)
Pituitary tumours are classified by the characteristic clinical syndromes that accompany tumour hormone production. All of the constituent hormone-secreting cell types of the anterior pituitary are capable of undergoing neoplastic change, although it
Autor:
N. J. L. Gittoes
Publikováno v:
Journal of clinical pharmacy and therapeutics. 19(3)
Over recent years the pharmacological treatment strategy for rheumatoid arthritis (RA) has changed. An early, aggressive approach has been adopted with a view to maintaining functional capacity. The changing role of nonsteroidal anti-inflammatory age