Zobrazeno 1 - 10
of 42
pro vyhledávání: '"N J, van Sittert"'
Autor:
E.J. Brouwer, N. J. Van Sittert, Peter J. Boogaard, F. A. De Wolff, L.J. Bloemen, R.F.M. Herber, A.J.W. Verplanke
Publikováno v:
Occupational and Environmental Medicine, 57, 745-751. BMJ Publishing Group
OBJECTIVES—To investigate the possible effects of occupational exposure to the nematocide cis-1,3-dichloropropene (cis-DCP) on function of the kidney and liver in the starch potato growing region in The Netherlands. METHODS—The study involved 13
Autor:
P. A. Van Elburg, N. J. Van Sittert, K. A. Richardson, R. H. J. J. J. Megens, James A. Bond, Peter J. Boogaard, Michele A. Medinsky, William P. Watson, M. M. C. G. Peters, Ewan D. Booth, Brian A. Wong
Publikováno v:
Toxicological Sciences. 49:186-201
1,3-Butadiene (butadiene) is a potent carcinogen in mice, but not in rats. Metabolic studies may provide an explanation of these species differences and their relevance to humans. Male Sprague-Dawley rats and B6C3F1 mice were exposed for 6 h to 200 p
Publikováno v:
Xenobiotica. 29:987-1006
The inactivation of 2-oxiranylmethyl 2-ethyl-2,5-dimethylhexanoate (C10GE), one of the most abundant isomers of the epoxy-resin Carduras E-10 glycidyl ester, was studied in subcellular fractions of human, C3H mouse and F344 rat liver, lung and skin.
Autor:
Peter J. Boogaard, N. J. Van Sittert
Publikováno v:
Scopus-Elsevier
Environmental Health Perspectives
Environmental Health Perspectives
Phenol is not reliable as a biomarker for exposure to benzene at concentrations below 5 ppm (8-hr time-weighted average [TWA]). S-Phenylmercapturic acid (S-PMA) and trans-trans-muconic acid (tt-MA), two minor urinary metabolites of benzene, have been
Publikováno v:
Biometrika. 83:683-687
SUMMARY The problem of testing homogeneity of many within-subject variances using small samples is addressed. The asymptotic null distribution of minus twice the likelihood ratio statistic, as the number of subjects tends to infinity, is derived. By
Publikováno v:
Scopus-Elsevier
The evaluation of a biochemical or hematological quantity measured in a study group of employees during occupational health assessments involves a comparison with a reference sample group. Part of this evaluation consists of checking whether the perc
Publikováno v:
Occupational and Environmental Medicine. 50:603-612
Renal changes with time have been studied in 14 workers engaged in the production of cadmium (Cd) in a zinc ore refinery. These workers were examined once a year in the period 1980 to 1985 and 13 of them also in 1989. Four of the workers (group A) ha
Publikováno v:
Scopus-Elsevier
An assessment has been made of biochemical alterations in renal and hepatic functions of 73 male operators employed for an average of 8.2 years (range 0.5-23 years) in a chemical plant producing chlorinated hydrocarbons. Exposure to allyl chloride (A
Publikováno v:
Environmental Health Perspectives
In a study on workers in a chemical plant where ethylene oxide (EtO) is manufactured and partly used for ethylene glycol production, exposure to EtO was monitored during annual periodic health assessments in January 1988, December 1988, and March 199
Autor:
L. Wazneh, Margareta Törnqvist, Alan M. Jeffrey, P. B. Farmer, A.-L. Magnusson, Y.S. Tang, H. Van Der Waal, G. D. T. Beulink, N. J. Van Sittert
Publikováno v:
Analytical Biochemistry. 203:357-360
Hemoglobin adducts are useful for the identification and quantification of electrophilic agents in vivo. A modified Edman degradation method has been extensively used for monitoring exposure to ethylene oxide through gas chromatographic-mass spectrom