Zobrazeno 1 - 10
of 32
pro vyhledávání: '"N J, de Both"'
Autor:
N. A. Jenkins, J. N. Ihle, D. J. Gilbert, Peter J. M. Valk, David S. Askew, Yolanda Vankan, Bob Löwenberg, N. J. De Both, N. G. Copeland, Samantha Hol, Ruud Delwel
Publikováno v:
Europe PubMed Central
A new common region of virus integration, Evi11, has been identified in two retrovirally induced murine myeloid leukemia cell lines, NFS107 and NFS78. By interspecific backcross analysis, it was shown that Evi11 is located at the distal end of mouse
Publikováno v:
Biochemical Journal. 278:269-278
Screening a mouse genomic DNA library with human androgen-receptor (hAR) cDNA probes resulted in the isolation and characterization of eight genomic fragments that contain the eight exons of the mouse androgen-receptor (mAR) gene. On the basis of sim
Autor:
N J, De Both
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 145(44)
Therapeutic cloning has become possible since the discovery that nuclei from somatic cells of adult animal tissue can successfully be used for cloning and the fact that human embryonic stem cell lines have been established from preimplantation embryo
Publikováno v:
International journal of cancer. 86(4)
Beta-catenin has been identified as an oncogene. Phosphorylation of sites encoded by exon 3 of the beta-catenin gene facilitates degradation of this protein by the adenomatous polyposis coli (apc) gene product. Mutations in these sites or inactivatio
Publikováno v:
International journal of cancer. 72(6)
It is generally assumed that tumor progression is a microevolutionary process in which increasingly aggressive clones, generated through genetic instability, emerge in an initially monoclonal lesion. The present study was undertaken to determine how
Publikováno v:
Leukemia. 4(1)
The Friend viruses, like the Rauscher virus, cause murine acute erythroleukemias which evolve in a similar multistep process. In previous studies it has been described that the late malignant proerythroblastic transformation induced by the polycythem
Autor:
M. Vermey, N. J. De Both
Publikováno v:
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. 29:17-26
SummaryThe regeneration capacities of normal and transposed small bowel epithelium were compared in rats after applying high doses of X-irradiation.It has been shown that the potency of the mucosa to regenerate is much higher than assumed and that th
Autor:
P. E. Zondervan, E. H. Rhijnsburger, G. van Houwelingen, N. J. De Both, J. L. M. van Gaalen, D. Berends
Publikováno v:
International Journal of Cancer. 42:112-118
Hybridomas producing syngeneic monoclonal antibodies (MAbs) were prepared by fusion of spleen cells of BALB/c mice, which were immunized with sublethal doses of RMB-I cells. This cell line originates from a Rauscher virus (R-MuLV)-induced myeloid leu
Publikováno v:
Leukemia Research, 11(1), 25-30. Elsevier Ltd.
Rauscher murine leukemia virus-induced erythroid, lymphoid and myeloid cell lines were characterized with respect to the expression of differentiation antigens using a panel of monoclonal antibodies. The expression of differentiation antigens was mea
Publikováno v:
International Journal of Cancer. 42:42-47
A syngeneic monoclonal antibody (MAb) (IC5F5) was successfully used in the immunotherapy of Rauscher-virus-induced myeloid leukemic RMB-I cells. It is directed to a virus-encoded, but aberrantly processed protein, which is expressed on the cell membr