Zobrazeno 1 - 10
of 24
pro vyhledávání: '"N J, Schork"'
Publikováno v:
Cambridge Prisms: Precision Medicine, Vol 1 (2023)
Studies on humans that exploit contemporary data-intensive, high-throughput ‘omic’ assay technologies, such as genomics, transcriptomics, proteomics and metabolomics, have unequivocally revealed that humans differ greatly at the molecular level.
Externí odkaz:
https://doaj.org/article/36692c152ebf4f0d8dd37d74fbe71080
Autor:
J. S. Talboom, M. D. De Both, M. A. Naymik, A. M. Schmidt, C. R. Lewis, W. M. Jepsen, A. K. Håberg, T. Rundek, B. E. Levin, S. Hoscheidt, Y. Bolla, R. D. Brinton, N. J. Schork, M. Hay, C. A. Barnes, E. Glisky, L. Ryan, M. J. Huentelman
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-18 (2021)
Abstract To identify potential factors influencing age-related cognitive decline and disease, we created MindCrowd. MindCrowd is a cross-sectional web-based assessment of simple visual (sv) reaction time (RT) and paired-associate learning (PAL). svRT
Externí odkaz:
https://doaj.org/article/fa0aca7984c542429f315df100c18eec
Autor:
N J, Schork, K, Nazor
Publikováno v:
Advances in genetics. 97
Individualized medicine, or the tailoring of therapeutic interventions to a patient’s unique genetic, biochemical, physiological, exposure and behavioral profile, has been enhanced, if not enabled, by modern biomedical technologies such as high-thr
Publikováno v:
Genes, brain, and behavior. 15(6)
Impulsivity is a multi-faceted construct that, while characterized by a set of correlated dimensions, is centered around a core definition that involves acting suddenly in an unplanned manner without consideration for the consequences of such behavio
Publikováno v:
Clinical genetics. 87(3)
Individuals who undergo multiplex direct-to-consumer (DTC) genomic testing receive genetic risk results for multiple conditions. To date, research has not investigated the influence of individual differences in disease perceptions among consumers on
Autor:
S. Ghosh, N. J. Schork
Publikováno v:
Diabetes. 45:1-14
Publikováno v:
Clinical genetics. 58(4)
In this review, we consider the motivation behind contemporary single nucleotide polymorphism (SNP) initiatives. Many of these initiatives are projected to involve large, population-based surveys. We therefore emphasize the utility of SNPs for geneti
Autor:
N J, Schork
Publikováno v:
Advances in genetics. 42
Standard DNA marker-based approaches to mapping genes that influence complex traits typically consider a limited number of hypotheses. Most of these hypotheses concentrate on the effect of a single individual locus (or relatively few loci) on the tra
Publikováno v:
Advances in genetics. 42
The case-control study design has been a veritable workhorse in epidemiological research since its inception and acceptance as a valid and valued field of inquiry. The reasons for this owe to the simplicity of the required sampling and the (potential
Publikováno v:
Trends in genetics : TIG. 16(3)
The challenge faced by research into the genetic basis of complex disease is to identify genes of small relative effect against a background of substantial genetic and environmental variation. This has focused interest on a classical epidemiological