Zobrazeno 1 - 10
of 12
pro vyhledávání: '"N J, Maihle"'
Publikováno v:
Journal of Cell Science. 113:935-942
Mutations in the ligand-binding domain of the epidermal growth factor receptor have been identified in several types of human cancers, including malignant gliomas. These mutations render signaling by this receptor to be constitutively ligand-independ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b208d04ca9a9dc3114dac0d902f92a8
https://doi.org/10.1242/jcs.113.6.935
https://doi.org/10.1242/jcs.113.6.935
Publikováno v:
Molecular and Cellular Biology. 14:7527-7534
The intrinsic tyrosine kinase activity of the epidermal growth factor receptor (EGFR) has been shown to be responsible for many of the pleiotropic intracellular effects resulting from ligand stimulation [W.S. Chen, C.S. Lazar, M. Poenie, R.Y. Tsien,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5183d78d9056c173b0aacdfabdc422
https://doi.org/10.1128/mcb.14.11.7527-7534.1994
https://doi.org/10.1128/mcb.14.11.7527-7534.1994
Autor:
N J, Maihle, A T, Baron, B A, Barrette, C H, Boardman, T A, Christensen, E M, Cora, J M, Faupel-Badger, T, Greenwood, S C, Juneja, J M, Lafky, H, Lee, J L, Reiter, K C, Podratz
Publikováno v:
Cancer treatment and research. 107
In summary, the EGF/ErbB family of receptor tyrosine kinases has been shown to play a key role in normal ovarian follicle development, and cell growth regulation of the ovarian surface epithelium. Disregulation of these normal growth regulatory pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0c371ecffddcf4c3e2c5a684afd9e67
https://pubmed.ncbi.nlm.nih.gov/11775453
https://pubmed.ncbi.nlm.nih.gov/11775453
Autor:
A T, Baron, J M, Lafky, V J, Suman, D W, Hillman, M C, Buenafe, C H, Boardman, K C, Podratz, E A, Perez, N J, Maihle
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(11)
Soluble ErbB (sErbB) growth factor receptors are being investigated as cancer biomarkers. Gonadotropic and steroid hormones have been shown to modulate the expression of ERBB family members in vivo. Accordingly, the range of sErbB1 values and their r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c05de79cf03bac027c98faaeea5016ac
https://pubmed.ncbi.nlm.nih.gov/11700266
https://pubmed.ncbi.nlm.nih.gov/11700266
Publikováno v:
Cancer research. 61(11)
A variety of receptor-mediated signaling pathways are controlled by both positive and negative extracellular regulators. In this study, we demonstrate that a naturally occurring secreted form of the human ErbB3 receptor, p85-soluble ErbB3 (sErbB3), i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63c45eeafd8119a9623cc8ee5173ebd8
https://pubmed.ncbi.nlm.nih.gov/11389077
https://pubmed.ncbi.nlm.nih.gov/11389077
Publikováno v:
Cancer research. 60(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ac61d0076e497a723bb238e50ee1b59
https://pubmed.ncbi.nlm.nih.gov/10463620
https://pubmed.ncbi.nlm.nih.gov/10463620
Autor:
A T, Baron, J M, Lafky, C H, Boardman, S, Balasubramaniam, V J, Suman, K C, Podratz, N J, Maihle
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 8(2)
Epithelial ovarian cancer (EOC) has a high mortality rate, which is due primarily to the fact that early clinical symptoms are vague and nonspecific; hence, this disease often goes undetected and untreated until in its advanced stages. Sensitive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29385e38e35e2e7b9ece109593bdc8af
https://pubmed.ncbi.nlm.nih.gov/10067810
https://pubmed.ncbi.nlm.nih.gov/10067810
Publikováno v:
Cancer. 83(9)
Prostate carcinoma usually is heterogeneous and multifocal, with diverse clinical and morphologic manifestations. Understanding of the molecular basis for this heterogeneity is limited, particularly for the putative precursor, high grade prostatic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c07288c47241983adeaad0f02e630792
https://pubmed.ncbi.nlm.nih.gov/9806659
https://pubmed.ncbi.nlm.nih.gov/9806659
Autor:
J A, Lust, D F, Jelinek, K A, Donovan, L A, Frederick, B K, Huntley, J K, Braaten, N J, Maihle
Publikováno v:
Current topics in microbiology and immunology. 194
Soluble receptors have been shown to be potent immunomodulators of their respective ligands. Since IL-6 is a central growth factor for myeloma cells, an sIL-6R may modulate IL-6 activity. We have previously reported a novel IL-6R mRNA from myeloma ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adab82e4139254636ba97b160831f39d
https://pubmed.ncbi.nlm.nih.gov/7895493
https://pubmed.ncbi.nlm.nih.gov/7895493
Autor:
D B, Schowalter, W P, Sullivan, N J, Maihle, A D, Dobson, O M, Conneely, B W, O'Malley, D O, Toft
Publikováno v:
The Journal of biological chemistry. 266(31)
In this study a model system for expression of the chicken progesterone receptor in cultured cells was developed using a quail fibroblast cell line, QT6. The chicken progesterone receptor form A expressed in QT6 cells was evaluated and determined to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::955c3cb330de20637045e24b82e39d02
https://pubmed.ncbi.nlm.nih.gov/1939158
https://pubmed.ncbi.nlm.nih.gov/1939158