Zobrazeno 1 - 10
of 36
pro vyhledávání: '"N J, MacDonald"'
Publikováno v:
Archives of Orthopaedic and Trauma Surgery. 142:1769-1773
The majority of neck of femur (NOF) fracture patients are frail and at a higher risk of cardiac arrest. This makes discussion of treatment escalation vital to informed care. The optimal time for these discussions is prior to admission or trauma. Howe
Autor:
C Speake, A Pichugin, T Sahu, V Malkov, R Morrison, Y Pei, L Juompan, N Milman, S Zarling, C Anderson, N J MacDonald, S Wong-Madden, J Wendler, A Ishizuka, Z W MacMillen, V Garcia, S H Kappe, U Krzych, P E Duffy
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165489 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0159449.].
Externí odkaz:
https://doaj.org/article/3daefafa2af7436985f1a9a7168618a9
Publikováno v:
Archives of orthopaedic and trauma surgery. 142(8)
The majority of neck of femur (NOF) fracture patients are frail and at a higher risk of cardiac arrest. This makes discussion of treatment escalation vital to informed care. The optimal time for these discussions is prior to admission or trauma. Howe
Publikováno v:
The Journal of small animal practiceReferences. 61(6)
OBJECTIVES To investigate the effect of breed as a risk factor associated with humeral condylar fracture in skeletally immature dogs in the UK. MATERIALS AND METHODS Retrospective study of dogs under 12 months of age that were presented with humeral
Publikováno v:
Cancer and Metastasis Reviews. 19:181-190
Considerable progress has been made in the understanding of the molecular structure and mechanistic aspects of Angiostatin and Endostatin, endogenous angiogenesis inhibitors that have been shown to regress tumors in murine models. The growing body of
Autor:
N J, MacDonald, W Y, Shivers, D L, Narum, S M, Plum, J N, Wingard, S R, Fuhrmann, H, Liang, J, Holland-Linn, D H, Chen, B K, Sim
Publikováno v:
The Journal of biological chemistry. 276(27)
The mechanism of action of Endostatin, an endogenous inhibitor of angiogenesis and tumor growth, remains unknown. We utilized phage-display technology to identify polypeptides that mimic the binding domains of proteins with which Endostatin interacts
Publikováno v:
Cancer metastasis reviews. 19(1-2)
Considerable progress has been made in the understanding of the molecular structure and mechanistic aspects of Angiostatin and Endostatin, endogenous angiogenesis inhibitors that have been shown to regress tumors in murine models. The growing body of
Publikováno v:
Biochemical Society symposium. 63
The nm23 genes were discovered on the basis of their reduced expression by highly metastatic cell lines. This trend was confirmed in cohorts of several types of human carcinomas and melanomas. Several transfection studies have demonstrated the suppre
Publikováno v:
The Journal of biological chemistry. 272(9)
We previously compared the structure and motility suppressive capacity of nm23-H1 by transfection of wild type and site-directed mutant forms into breast carcinoma cells. Wild type nm23-H1 and an nm23-H1(S44A) (serine 44 to alanine) mutant suppressed
Publikováno v:
The Journal of biological chemistry. 271(41)
We report the first correlation of Nm23 sequence and its tumor metastasis-suppressive capacity using site-directed mutagenesis and an in vitro tumor cell motility assay. MDA-MB-435 human breast carcinoma cells were transfected with a control expressi