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Growth and Growth Hormone Therapy of Children Treated for Leukaemia

Autor: Christopher T. Cowell, Bin Moore, M. Silink, N. J. Howard, Michael M. Stevens, M Jimenez, C A Quigley, Margaret A. Menser, Mary Bergin, Judy A. Kirk

Publikováno v: Acta Paediatrica. 77:152-161

A total of 37 children (24 male, 13 female) who had been treated for leukaemia with chemotherapy and 24 Gy cranial irradiation, and who were disease free for at least 18 months, were commenced on somatrem at a mean of 7.6 years (range, 4.8-12.1 years

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b456bc1f8293ca46e8942d844ecfbe
https://doi.org/10.1111/j.1651-2227.1988.tb10816.x

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Growth in children with X-linked hypophosphataemic rickets

Autor: M. Silink, N. J. Howard, Christopher T. Cowell, Kim C. Donaghue, Charles F. Verge

Publikováno v: Acta Paediatrica. 82:70-75

Currently, X-linked hypophosphataemic rickets (XLHR) is most commonly treated with a combination of phosphate and vitamin D, but there is conflicting evidence about the effects of this treatment on linear growth. In all, 25 patients with XLHR (curren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e4c082286741bfc6fb4101cbafd852
https://doi.org/10.1111/j.1651-2227.1993.tb12848.x

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Benign intracranial hypertension and recombinant growth hormone therapy in Australia and New Zealand

Autor: PA Crock, LK Shield, W Cutfield, AM Nicoll, JD McKenzie, G Byrne, N. J. Howard

Publikováno v: Acta Paediatrica. 87:381-386

Benign intracranial hypertension (BIH) is reported in three children from Australia and one from New Zealand, who were being treated with recombinant human growth hormone (rhGH). Three males and one female, aged between 10.5 and 14.2 y, developed int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b70b67e4e5bfcc7dcd3ae2b05070327e
https://doi.org/10.1111/j.1651-2227.1998.tb01463.x

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Graves’ disease in children less than 8 years of age: review of clinical features and treatment outcome

Autor: Paul Z. Benitez-Aguirre, Kim C. Donaghue, M. Silink, Geoffrey Ambler, Maria E. Craig, Christopher T. Cowell, N. J. Howard, Shubha Srinivasan, Sophy Korula

Publikováno v: International Journal of Pediatric Endocrinology

Results Sixteen patients (2 males) were identified with median age at diagnosis of 4.96 years (range 2.5-7.83). Presenting symptoms were hyperactivity, weight loss, poor sleep and diarrhoea. They had predominant non-Anglo-Saxon ethnicity. Significant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef15fe20c55a6f60d9f32885673c360
https://doi.org/10.1186/1687-9856-2015-s1-p102

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Response to growth hormone therapy and gonadal pathology in 45,X/46,XY females

Autor: Christopher T. Cowell, Bin Moore, Geoffrey R Ambler, Paul Z. Benitez-Aguirre, Andrew Biggin, Angela Titmuss, N. J. Howard, Maria E. Craig, Shubha Srinivasan

Publikováno v: International Journal of Pediatric Endocrinology

Turner syndrome (TS) and related sex chromosome abnormalities are associated with a variety of karyotypes and phenotypes affecting 1 in 2500 live births. Mosaicism with Y material (45,X/46,XY) and female phenotype is rare (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7842dbb9526480df2b09400511c81988
https://doi.org/10.1186/1687-9856-2015-s1-o54

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Combined pituitary hormone deficiency in Australian children: clinical and genetic correlates

Autor: James L. Penfold, Michael J. Thomsett, Y. Jeske, Kim McLennan, Catherine S. Choong, Andrew Cotterill, N. J. Howard, Timothy W. Jones, David Cowley

Publikováno v: Clinical Endocrinology. 58:785-794

Summary objective Mutations in the gene for the POU domain transcription factor POU1F1 (human Pit-1) have been reported in patients with GH, TSH and PRL deficiencies. PROP1 (Prophet of Pit-1) gene mutations also cause gonadotrophin deficiencies and i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92dfa4903c75e1650ba05277b9812743
https://doi.org/10.1046/j.1365-2265.2003.01781.x

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