Zobrazeno 1 - 7
of 7
pro vyhledávání: '"N J, Gittoes"'
Publikováno v:
Pituitary. 1(2)
Estrogen (E2), acting via its nuclear receptors, has been implicated in tumor development and growth, particularly in the pathogenesis of breast cancer. E2 also modulates anterior pituitary hormone production and is a potent cell mitogen. Until recen
Publikováno v:
Clinical endocrinology. 50(6)
The MEN1 gene on chromosome 11q13 encodes a tumour suppressor gene, mutations in which cause multiple endocrine neoplasia (MEN) type 1 syndrome. Loss of heterozygosity (LOH) at this locus is a common finding amongst sporadic pituitary tumours. We hav
Publikováno v:
The Journal of clinical endocrinology and metabolism. 84(2)
We previously reported that nonfunctioning tumors of the anterior pituitary exhibit reduced expression of thyroid receptor (TR) alpha and beta isoforms, an observation that may account for abnormalities of T3-mediated negative regulation of the glyco
Publikováno v:
Clinical endocrinology. 48(4)
The glycoprotein hormone common alpha-subunit is frequently expressed in clinically 'non-functioning' tumours (NFTs) of the anterior pituitary, despite normal levels of T3 and gonadal steroids. This observation suggests abnormal negative-feedback reg
Retinoid X receptor gamma mRNA expression is reduced in recurrent non-functioning pituitary adenomas
Publikováno v:
Clinical endocrinology. 48(4)
Publikováno v:
Clinical endocrinology. 48(3)
Pituitary radiotherapy (RT) is often used as adjuvant treatment in the post-operative period for patients with clinically non-functioning pituitary tumours (NFTs). There is a distinct lack of objective data, however, describing the efficacy of RT in
Publikováno v:
The Journal of clinical endocrinology and metabolism. 82(6)
Nonfunctioning tumors (NFTs) of the anterior pituitary often express elevated levels of the glycoprotein hormone alpha-subunit, which, under normal physiological conditions, is under negative feedback control by thyroid and gonadal steroid hormones.