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RP 73870, a gastrin/cholecystokinin-B receptor antagonist with potent anti-ulcer activity in the rat
Autor:
C E, Pendley, L R, Fitzpatrick, A J, Capolino, M A, Davis, N J, Esterline, A, Jakubowska, P, Bertrand, C, Guyon, M C, Dubroeucq, G E, Martin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(3)
RP 73870, the racemic potassium salt of (([N-(methoxy-3-phenyl)-N-(N-methyl-N-phenyl-carbamoylmethyl)- carbamoylmethyl]-3-ureido)-3-phenyl)-2-ethylsulfonate-(RS) is a potent, reversible antagonist of both gastrin and cholecystokinin-B receptors in gu