Zobrazeno 1 - 10
of 24
pro vyhledávání: '"N I Kerkvliet"'
Autor:
R A Prell, N I Kerkvliet
Publikováno v:
The Journal of Immunology. 158:2695-2703
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a highly toxic environmental contaminant, suppresses both CTL and cytotoxic alloantibody production in C57BL/6 mice challenged with allogeneic P815 tumor cells. Recent evidence suggests that TCDD interferes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6442300b06d1640d9b0cc7a19dfa4fa2
https://doi.org/10.4049/jimmunol.158.6.2695
https://doi.org/10.4049/jimmunol.158.6.2695
Publikováno v:
The Journal of Immunology. 157:2310-2319
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a widespread environmental contaminant and prototypic ligand for the aryl hydrocarbon receptor, is a potent immunotoxicant. To understand the underlying mechanisms of TCDD immunotoxicity, we have characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9127df8db144e33bcf406e774f4644dc
https://doi.org/10.4049/jimmunol.157.6.2310
https://doi.org/10.4049/jimmunol.157.6.2310
Publikováno v:
European journal of immunology. 30(7)
Gamma-Glutamyltranspeptidase (GGT) catalyzes the first step in the extracellular hydrolysis of glutathione (GSH) and plays a critical role in GSH recycling; however, little is known about the impact of diminished GGT activity on immune function. We r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56704cc01218b9a7a97e783c3c8adbad
https://pubmed.ncbi.nlm.nih.gov/10940879
https://pubmed.ncbi.nlm.nih.gov/10940879
Autor:
D M, Shepherd, N I, Kerkvliet
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(5)
CD154 (CD40 ligand, gp39) interaction with its receptor CD40 has been shown to be critically important for the generation of cell-mediated as well as humoral immunity. It has been proposed that ligation of CD40 on APCs, presumably by activated Th cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37f01945ca35c8041ae8bd8daad15829
https://pubmed.ncbi.nlm.nih.gov/10452982
https://pubmed.ncbi.nlm.nih.gov/10452982
Autor:
G K, DeKrey, N I, Kerkvliet
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(2)
The intent of this study was to examine the effects of stress-like plasma corticosterone (CS) elevation on the generation of alloantigen-specific cytotoxic T lymphocyte (CTL) activity in mice. Elevation of plasma CS was achieved by infusion of exogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d175a1f14b820439d2588967858438ee
https://pubmed.ncbi.nlm.nih.gov/7752086
https://pubmed.ncbi.nlm.nih.gov/7752086
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(1)
The cytotoxic T lymphocyte (CTL) response to allogeneic P815 tumor in C57bl/6 mice is dose-dependently suppressed after treatment with 3,3',4,4',5,5'-hexachlorobiphenyl (HxCB). Elevation of plasma corticosterone (CS) is also observed coincident with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d0110b5c785d7b8671ae2602e8a9b89
https://pubmed.ncbi.nlm.nih.gov/8229756
https://pubmed.ncbi.nlm.nih.gov/8229756
Publikováno v:
International journal of immunopharmacology. 14(7)
An in vivo model to assess the effects of chemicals on T-cell activation has been characterized and validated using the immunosuppressive drug, cyclosporin A (CsA). The dose response and kinetic effects of the hamster anti-mouse monoclonal antibody 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba02e45dd7e1917b8556e5dfa07d6c55
https://pubmed.ncbi.nlm.nih.gov/1452414
https://pubmed.ncbi.nlm.nih.gov/1452414
Publikováno v:
Journal of the American Veterinary Medical Association. 201(2)
Investigations into the cause of health problems on a horse-breeding farm led to the discovery of high concentrations (630 to 9,810 mg/kg of bedding) of pentachlorophenol in wood shavings used as bedding for horses over a period of 2 to 4 years. Toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55465015ba93c3ae6b6de6405f592f83
https://pubmed.ncbi.nlm.nih.gov/1500327
https://pubmed.ncbi.nlm.nih.gov/1500327
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 20(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14f7e67ea72f6b9d65a0d16db7250c1b
https://pubmed.ncbi.nlm.nih.gov/1355726
https://pubmed.ncbi.nlm.nih.gov/1355726
Autor:
J A, Deyo, N I, Kerkvliet
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 14(4)
Monocrotaline (MCT) is a member of a class of compounds known as pyrrolizidine alkaloids (PAs). PAs are found in the leaves and seeds of a variety of plant species. The potential intoxication of livestock and man through the ingestion of contaminated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::483ca6f3bdd99f1684fee1261ef919ca
https://pubmed.ncbi.nlm.nih.gov/2113877
https://pubmed.ncbi.nlm.nih.gov/2113877