Zobrazeno 1 - 10
of 12
pro vyhledávání: '"N I, Stocks"'
Publikováno v:
The Journal of Immunology. 144:3266-3271
PBL from approximately 50% of asymptomatic individuals infected with HIV have been previously demonstrated to exhibit defective in vitro Th function that is selective for influenza A virus (FLU), but not for HLA alloantigens (ALLO). In this report, w
Publikováno v:
The Journal of Immunology. 144:2524-2528
In our study, we have measured in vitro proliferation and IL-2 production by human PBL to characterize the interactions between Th cells and accessory cells (AC) involved in responses to either conventional Ag or alloantigens. IL-2 production and pro
Autor:
Bonnie L. Bermas, Gene M. Shearer, N I Stocks, Daniel Goldman, Barbara B. Mittleman, Matthew W. Miller, Michelle Petri, Charles S. Via
Publikováno v:
Journal of clinical immunology. 14(3)
Patients with systemic lupus erythematosus (SLE) are known to have defects in both humoral and cellular immunity. The significance of defective T cell-mediated immunity and its relationship to disease activity have not been clearly established. We st
Publikováno v:
Clinical immunology and immunopathology. 54(2)
Peripheral blood mononuclear cells from human immunodeficiency virus seropositive (HIV+) individuals who did not exhibit symptoms of acquired immunodeficiency syndrome (AIDS) (Walter Reed Stage 1 patients) were tested for accessory cell function for
Autor:
Charles S. Via, N I Stocks, R.A. Zajac, Gene M. Shearer, Mario Clerici, Daniel R. Lucey, R.N. Boswell
Publikováno v:
Journal of Clinical Investigation. 84:1892-1899
We have tested the T helper cell (TH) potential of asymptomatic, HIV seropositive (HIV+) patients, using an in vitro assay for IL-2 production. Peripheral blood leukocytes (PBL) from 74 HIV+ patients and 70 HIV- control donors were tested for TH func
Publikováno v:
Journal of Clinical Investigation. 75:1957-1964
We studied the effects of sera from patients with the acquired immunodeficiency syndrome (AIDS) on interleukin-2 (IL-2) production to help elucidate the mechanism of immunodeficiency. Compared with sera from healthy controls, sera from AIDS patients
Autor:
Jay A. Berzofsky, R. Neal Boswell, Denise C. Bernstein, Dean L. Mann, Mario Clerici, Robert A. Zajac, N I Stocks, Gene M. Shearer
Publikováno v:
Nature. 339(6223)
T LYMPHOCYTES from mice1 and healthy humans2 immunized against the human immunodeficiency virus (HIV) envelope have recently been shown to recognize two antigenic regions of the gp160 HIV-envelope protein which have been located on the basis of amphi
Publikováno v:
Cellular immunology. 58(1)
The metabolic processes involved in the in vitro augmentation of mouse natural killer (NK) activity by interferon (IF) were studied. Augmentation occurred after a very brief (5–10 min), temperature-independent exposure of spleen cells to IF. This b
Publikováno v:
Journal of biological response modifiers. 4(6)
Intravenous infusions of 250,000 U of lymphocyte-derived or recombinant DNA-derived interleukin-2 (IL-2) were administered to patients with the acquired immunodeficiency syndrome, and sera were obtained for pharmacokinetic studies. A methodology was
Autor:
Jumes E. Balow, George C. Tsokos, Michael A. Phelan, Alain H. Rook, N I Stocks, Gerald V. Quinnan, Julie Y. Djeu, Keith M. Ramsey
Publikováno v:
Clinical immunology and immunopathology. 24(2)
Natural killer (NK) cell function is frequently depressed in systemic lupus erythematosus (SLE) and an NK cell inhibitory activity is present in the serum. In an effort to determine whether autoantibodies to NK cells are made by patients with SLE, se