Zobrazeno 1 - 10
of 28
pro vyhledávání: '"N I, Sheina"'
Autor:
V. A. Parshin, N. I. Sheina, A. V. Semeikin, T. A. Fedotcheva, N. L. Shimanovsky, V. A. Votyakov
Publikováno v:
Pharmaceutical Chemistry Journal. 55:215-218
The ability of gestobutanoyl, a pregnane steroid with progestogenic activity, to exhibit additional glucocorticoid, mineralocorticoid, antiandrogenic, and estrogenic effects in rats has been studied. It was found that gestobutanoyl did not have estro
Autor:
V. A. Parshin, T. A. Fedotcheva, L. I. Myalina, V. V. Kolesnikova, N. L. Shimanovskii, L. P. Sazonova, N. I. Sheina
Publikováno v:
Pharmaceutical Chemistry Journal. 54:439-443
The generative function of female rats upon intragastric administration of tablets of gestobutanoil at doses of 0.25 and 2.5 mg/kg (calculated doses corresponding to the therapeutic dose and ten times higher) was studied. Gestobutanoil was administer
Autor:
N. I. Sheina, Nadezhda I. Fedotcheva, T. A. Fedotcheva, E. D. Sveshnikova, Mikhail N. Sokolov, Konstantin V. Kudryavtsev, N. L. Shimanovskii
Publikováno v:
Pharmaceutical Chemistry Journal. 54:119-125
New mepregenol 17-acetate derivatives with potential cytotoxicity were synthesized. Mepregenol 17-acetate 3-acrylate (III) was shown to exhibit potent cytotoxicity although the ester of N-benzylpyrrolidine-3-carboxylic acid (IV) had weaker activity t
Publikováno v:
Toxicological Review. :28-36
A study of the embryo- and fetotoxic effects registered in the antenatal and postnatal periods of development after the intragastric administration of Gestobutanoil in two doses (equitherapeutic and 10 times higher) has been performed. It has been fo
Publikováno v:
Toxicological Review. :28-33
Safety in the use of GMO for food purposes and public opinion on the problem are discussed. It is shown that the awareness of respondents on GMO has increased since 2011 to 2016. However, middle-aged and elderly respondents treat with care their cont
Autor:
L. I. Myalina, V. V. Kolesnikova, N. I. Sheina, E. V. Budanova, J. G. Skryabina, G. G. Chub, L. P. Sazonova
Publikováno v:
Toxicological Review. :48-50
Strain Pseudomonas aureofaciens BKM-2391Д recovered from the soil arounel oat rhizosnhere is not a genetically modified strain. Based on investigations performed, the following hygiene norms are recommended for the strain Pseudomonas aureofaciens BK
Autor:
L. I. Myalina, E. V. Budanova, G. G. Chub, J. G. Skryabina, N. I. Sheina, L. P. Sazonova, V. V. Kolesnikova
Publikováno v:
Toxicological Review. :58-60
Hazard and toxicity assessment of the microorganism Bacillus Komagataella (Pichia)pastoris ВKПМ Y-4225 was performed. In accordance with legislative regulatory documents in force for its congener in taxonomic aspect of cytochrome C producer strain
Publikováno v:
Toxicological Review. :51-52
The preparation “Phytase” is low-toxic, does not have an irritant and sensitizing effect. The threshold of acute inhalation of the preparation is set at the level of 28.0 mg/m3 (on phytase) according to the change in the function of the nervous s
Publikováno v:
Gigiena i sanitariia. (6)
There is considered problem of the negative human impact on the environment in Russia and the countries of southwest Asia. The adverse impact of high-fluoride and high-arsenic drinking water in artificial endemic provinces and increased radiation bac
Publikováno v:
Gigiena i sanitariia. (2)
The question of need for standardization and validation of the complex methods to establish the maximum concentration limit (MCL) ofbiotechnological strains in the water of water bodies is under discussion. On the basis of the experimental studies it