Zobrazeno 1 - 10
of 65
pro vyhledávání: '"N I, Kukushkin"'
Autor:
A. A. Temnov, Astrelina Ta, N. I. Kukushkin, E. V. Gorina, A. S. Samoilov, I. Kobzeva, D.Yu. Usupzhanova, S. P. Krechetov, Yu. B. Suchkova, Sklifas An
Publikováno v:
Biophysics. 64:224-232
The effect of different polyoxyethylene–polyoxypropylene triblock copolymers, their concentration, and mode of action on the loading of poly-(lactic-co-glycolic acid) copolymer-based microparticles containing such medicinal agents as radachlorin (c
Autor:
A. A. Temnov, Sklifas An, V. K. Zhalimov, N. I. Kukushkin, Nikita V. Penkov, Vladimir Kaptsov
Publikováno v:
Colloid and Polymer Science. 296:251-257
Nonionic surfactants, triblock copolymers (TBCs), were used to obtain and stabilize perfluorocarbon emulsions in a water solution (drop size, 200–300 nm). These TBCs differ in their molecular weight, length of polyethylene glycol (PEG) or polypropy
Autor:
N. N. Salmov, Yulia Gritsyna, Ivan M. Vikhlyantsev, A. D. Ulanova, A. G. Bobylev, Zoya A. Podlubnaya, N. I. Kukushkin
Publikováno v:
Alcoholism: Clinical and Experimental Research. 41:1686-1694
BACKGROUND Proteolysis can proceed via several distinct pathways such as the lysosomal, calcium-dependent, and ubiquitin-proteasome-dependent pathways. Calpains are the main proteases that cleave a large variety of proteins, including the giant sarco
Publikováno v:
Biophysics. 62:12-16
The composition of plasma proteins adsorbed on the surface of perfluorocarbon emulsions stabilized by different triblock copolymers and their quantitative ratio were analyzed. The results allowed us to describe three types of protein adsorption on th
Autor:
Ivan M. Vikhlyantsev, A. G. Bobylev, Zoya A. Podlubnaya, N. N. Salmov, I S Fadeeva, Yu. V. Gritsyna, N. I. Fesenko, D. G. Sadikova, N. I. Kukushkin
Publikováno v:
Biochemistry. Biokhimiia. 82(2)
Enzymatic activity of Ca2+-dependent calpain proteases as well as the content and gene expression of μ-calpain (activated by micromolar calcium ion concentrations), calpastatin (inhibitor of calpains), and titin (substrate for calpains) were investi
Publikováno v:
Biophysics. 57:796-803
The effects of insulin (0.1-50 nM) on isometric twitch force (0.1 to 1.0 Hz; 30 +/- 1 degree C; 1.8 mM Ca(2+)) were studied in right ventricular papillary muscles from active ground squirrels of different seasons (summer, n = 14; autumn, n = 16 and w
Publikováno v:
Biophysics. 57:222-228
The adsorption abilities of the perfluorocarbon emulsion stabilized by Proxanol 268 were investigated in vitro and in vivo. In vitro, the saturation point for the blood plasma proteins was nearly reached after five minutes of incubation of the emulsi
Publikováno v:
Biophysics. 57:215-221
It has been shown that sorption of most proteins with the molecular weight lower than 200 kDa from human blood plasma on the surface of perfluorocarbon emulsion stabilized with proxanol 268 is mainly based on hydrophobic interaction, whereas sorption
Autor:
E. E. Fesenko, V. K. Ravin, A. D. Sofin, Vladimir I. Novoselov, Mars G. Sharapov, N. I. Kukushkin
Publikováno v:
Biophysics. 56:836-842
The possibility of using modified peroxiredoxins as powerful antioxidant agents has been considered. Peroxiredoxins immobilized on perfluorocarbon emulsions and PTD-modified peroxiredoxins have been studied. It has been shown that peroxiredoxins effi
Publikováno v:
Biophysics. 55:971-976
It has been shown that, upon incubation of mouse bone marrow stem cells (BMSC) in vitro with the nanoparticles of perfluorocarbon (PFC) emulsion stabilized by proxanol 268, these nanoparticles penetrate into cells and stay there for a long time (up t