Zobrazeno 1 - 10
of 38
pro vyhledávání: '"N I, Baram"'
Autor:
Elmira Tokhtaeva, Khairulla Ziyaev, Maksim Ionov, N. Gordiyenko, Maria Zamaraeva, Kuralbay Rezhepov, Izabela Zukowska, Olga A. Mareninova, N. I. Baram
Publikováno v:
International Journal of Biological Macromolecules. 51:908-914
The objective of this study is analysis of stability and antioxidant and antiradical activities of the gossypol derivative - megosin conjugated with N-polyvinylpyrrolidone (PVP). The results of study have shown the greater stability of megosin+PVP th
Autor:
Maksim Ionov, Khairulla Zijaev, Ewa Olchowik, Maria Zamaraeva, B. A. Salakhutdinov, N. I. Baram, N. Gordiyenko, Maria Bryszewska
Publikováno v:
Journal of Medicinal Chemistry. 52:4119-4125
The conjugate of the gossypol derivative megosin (1) with N-polyvinylpyrrolidone named rometin (2) was synthesized. The effects of 1 and 2 on the structure and permeability of human erythrocytes and rat liver mitochondria were compared. Compound 1 in
Publikováno v:
Chemistry of Natural Compounds. 40:199-205
Autor:
N. I. Baram, Kh. L. Ziyaev, M. G. Levkovich, A. I. Ismailov, K. Zh. Rezhepov, A. M. Saiitkulov, F. G. Kamaev
Publikováno v:
Chemistry of Natural Compounds. 39:358-361
Azo-coupling of diazotized aromatic amines with gossypol and gossypolimines was studied. The physicochemical properties and interferon-inducing activity of the products were determined. It was found that the interferon-inducing activity depended on t
Publikováno v:
Chemistry of Natural Compounds. 38:319-322
New azo-derivatives of gossypol and its imines were described. Their physicochemical properties and data on their interferon-inducing activity were presented.
Publikováno v:
Chemistry of Natural Compounds. 36:185-188
New azo derivatives of gossypol are described. Their physicochemical properties are reported. The presence of hydroxyazo- and quinonhydrazo-tautomers is proposed.
Publikováno v:
Chemistry of Natural Compounds. 35:29-32
The results are given of a study of the hydrolysis of alkyl- and heterylimines of gossypol at various pH values.
Autor:
Kh. L. Ziyaev, B. Khodzhaniyazov, A. I. Ismailov, L. Biktimirov, F. G. Kamaev, N. I. Baram, S. B. Dzhurabekova
Publikováno v:
Chemistry of Natural Compounds. 34:38-41
The results are given of a study of gossypol, its physiologically active derivatives, and their complexes with N-polyvinylpyrrolidone (M.m. 8000) in various media. It has been shown that the production of complexes permits the creation not only of wa
Publikováno v:
Chemistry of Natural Compounds. 33:636-641
The method of obtaining radioactively labeled14C-gossypol-acetic acid has been improved: from it have been synthesized14C-derivatives of gossypol and their complexes with N-polyvinylpyrrolidone. A comparative study has been made of the pharmacokineti
Autor:
A. I. Gagel'gans, N. I. Baram, N. V. Gordienko, Kh. L. Ziyaev, A. I. Ismailov, A. Biktimirov, M. V. Zamaraeva
Publikováno v:
Chemistry of Natural Compounds. 31:315-320
It has beeen shown that water-soluble complexes of gossypol derivatives obtained by their immobilization on polyvinylpyrrolidone posses a lower membrane activity than the initial substances. The degree of interaction of the substances under investiga