Zobrazeno 1 - 10
of 676
pro vyhledávání: '"N Hutchinson"'
Publikováno v:
Endangered Species Research, Vol 53, Pp 363-378 (2024)
The bottlenose wedgefish Rhynchobatus australiae has experienced substantial population declines throughout its range. However, there is a lack of life history information (age, growth, and maturity) available for this species to inform conservation
Externí odkaz:
https://doaj.org/article/9323a72ddc124370ad5805f4e20a3f86
Autor:
David B. Chou, Brooke A. Furlong, Ryan R. Posey, Christos Kyprianou, Lucy R. O’Sullivan, Rhiannon David, Suzanne J. Randle, Urszula M. Polanska, Jon Travers, Jelena Urosevic, John N. Hutchinson, Jianwei Che, Anna M. Howley, Robert P. Hasserjian, Rachelle Prantil-Baun, Donald E. Ingber
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Patients treated with Aurora kinase inhibitors experience dose-limiting neutropenia while other cytopenias are rare. Here, Chou et al. show that this cell-type specific side effect is partly explained by loss of drug efflux pump expression during neu
Externí odkaz:
https://doaj.org/article/30b138eaa22049aea33459bc0a7f87f2
Autor:
Saranna Fanning, Haley Cirka, Jennifer L. Thies, Jooyoung Jeong, Sarah M. Niemi, Joon Yoon, Gary P. H. Ho, Julian A. Pacheco, Ulf Dettmer, Lei Liu, Clary B. Clish, Kevin J. Hodgetts, John N. Hutchinson, Christina R. Muratore, Guy A. Caldwell, Kim A. Caldwell, Dennis Selkoe
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract Synucleinopathy (Parkinson’s disease (PD); Lewy body dementia) disease-modifying treatments represent a huge unmet medical need. Although the PD-causing protein α-synuclein (αS) interacts with lipids and fatty acids (FA) physiologically
Externí odkaz:
https://doaj.org/article/a05e96cff1274ee38def6a5cf8769047
Autor:
Julia Rode, Hanna M. T. Edebol Carlman, Julia König, Dirk Repsilber, Ashley N. Hutchinson, Per Thunberg, Pernilla Andersson, Jonas Persson, Andrey Kiselev, Lori Lathrop Stern, Benita Salomon, Ahmed Abdulilah Mohammed, Jennifer S. Labus, Robert J. Brummer
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundEvidence from preclinical studies suggests that probiotics affect brain function via the microbiome-gut-brain axis, but evidence in humans remains limited.ObjectiveThe present proof-of-concept study investigated if a probiotic product conta
Externí odkaz:
https://doaj.org/article/96015bad9342440cbbc2b20315d37bf4
Autor:
Zhihui Wang, Mulong Du, Qianyu Yuan, Yichen Guo, John N. Hutchinson, Li Su, Yinan Zheng, Jun Wang, Lorelei A. Mucci, Xihong Lin, Lifang Hou, David C. Christiani
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 3, Pp 154-161 (2020)
Background: DNA methylation at the fifth position of cytosine (5mC) is a common epigenetic alteration affecting a range of cellular processes. In recent years, 5-hydroxymethylcytosine (5hmC), an oxidized form of 5mC, has risen broad interests as a po
Externí odkaz:
https://doaj.org/article/faf3f15181f14cba803506e4f73e2256
Autor:
Cuicui Wang, Andres Cardenas, John N. Hutchinson, Allan Just, Jonathan Heiss, Lifang Hou, Yinan Zheng, Brent A. Coull, Anna Kosheleva, Petros Koutrakis, Andrea A. Baccarelli, Joel D. Schwartz
Publikováno v:
Environment International, Vol 158, Iss , Pp 106955- (2022)
Background: Several epigenome-wide association studies (EWAS) of ambient particulate matter with aerodynamic diameter ≤ 2.5 µm (PM2.5) have been reported. However, EWAS of PM2.5 elements (PEs), reflecting different emission sources, are very limit
Externí odkaz:
https://doaj.org/article/99421bb313ed4d7c96a8a7bcf654cc96
Autor:
Julia Rode, Hanna M. T. Edebol Carlman, Julia König, Ashley N. Hutchinson, Per Thunberg, Jonas Persson, Robert J. Brummer
Publikováno v:
Cells, Vol 11, Iss 18, p 2922 (2022)
Probiotics can alter brain function via the gut–brain axis. We investigated the effect of a probiotic mixture containing Bifidobacterium longum, Lactobacillus helveticus and Lactiplantibacillus plantarum. In a randomized, placebo-controlled, double
Externí odkaz:
https://doaj.org/article/e82a3c43aa8e404e8ca0c3cdcb842baf
Autor:
Peiyan Ni, Haneul Noh, Zhicheng Shao, Qian Zhu, Youxin Guan, Joshua J. Park, Fatima Arif, James M. Park, Chiderah Abani, Cameron Beaudreault, Joy S. Park, Elizabeth Berry, Alexander Moghadam, Patric Stanton, John N. Hutchinson, Bill Andrews, Clare Faux, John Parnevelas, Leonard M. Eisenberg, Kyungjoon Park, Vadim Y. Bolshakov, Sangmi Chung
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 414-430 (2019)
During development, cortical interneurons (cINs) are generated from the ventral telencephalon, robustly migrate to the dorsal telencephalon, make local synaptic connections, and critically regulate brain circuitry by inhibiting other neurons. Thus, t
Externí odkaz:
https://doaj.org/article/66ad75cbb92c4f76b4426804c1f0cfa2
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Morphological diversity among closely related animals can be the result of differing growth patterns. The Australian radiation of agamid lizards (Amphibolurinae) exhibits great ecological and morphological diversity, which they ha
Externí odkaz:
https://doaj.org/article/235ad842bcc44547b6cdd4d8e309d4dd
Publikováno v:
Royal Society Open Science, Vol 8, Iss 2 (2021)
The diverse living Australian lizard fauna contrasts greatly with their limited Oligo-Miocene fossil record. New Oligo-Miocene fossil vertebrates from the Namba Formation (south of Lake Frome, South Australia) were uncovered from multiple expeditions
Externí odkaz:
https://doaj.org/article/f7130070a7294e73b737d58eae4e1d73