Zobrazeno 1 - 10
of 40
pro vyhledávání: '"N Helge, Meyer"'
Autor:
N. Helge Meyer, Nika Kotnik, Gaetan Aime Noubissi Nzeteu, Léon C. van Kempen, Mirjam Mastik, Maximilian Bockhorn, Achim Troja
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionColorectal cancer (CRC) ranks as the third most prevalent malignancy globally, with a concerning rise in incidence among young adults. Despite progress in understanding genetic predispositions and lifestyle risk factors, the intricate mol
Externí odkaz:
https://doaj.org/article/b123182399bb45d3be3cd4183e7868e4
Autor:
N. Helge Meyer, Claudia Corbo, Guillermo R. Castro, Goran Stjepanovic, Giada G. Genchi, Valerio Marino
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/36c21b2328ae40419cc71f12b32b49d4
Autor:
Gaetan Aime Noubissi Nzeteu, Bernhard F. Gibbs, Nika Kotnik, Achim Troja, Maximilian Bockhorn, N. Helge Meyer
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Pancreatic cancer (PC) has a complex and unique tumor microenvironment (TME). Due to the physical barrier formed by the desmoplastic stroma, the delivery of drugs to the tumor tissue is limited. The TME also contributes to resistance to various immun
Externí odkaz:
https://doaj.org/article/475189f468f740958d6e4c8a987b8398
Autor:
Gaetan Aime Noubissi Nzeteu, Stephanie Schlichtner, Sulamith David, Aylin Ruppenstein, Elizaveta Fasler-Kan, Ulrike Raap, Vadim V. Sumbayev, Bernhard F. Gibbs, N. Helge Meyer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recently, the V-domain immunoglobulin suppressor of T-cell activation (VISTA) was identified as a negative immune checkpoint regulator (NCR) that is mainly expressed in hematopoietic cells. Preclinical studies have shown that VISTA blockade results i
Externí odkaz:
https://doaj.org/article/efc8ca0dc2af46be88b2cef44b04ee93
Autor:
Stephanie Schlichtner, Inna M. Yasinska, Sabrina Ruggiero, Steffen M. Berger, Nijas Aliu, Mateja Prunk, Janko Kos, N. Helge Meyer, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Immune checkpoint proteins play crucial roles in human embryonic development but are also used by cancer cells to escape immune surveillance. These proteins and biochemical pathways associated with them form a complex machinery capable of blocking th
Externí odkaz:
https://doaj.org/article/df9cbb22cd0c4b25850127b6e31a3396
Autor:
Inna M. Yasinska, N. Helge Meyer, Stephanie Schlichtner, Rohanah Hussain, Giuliano Siligardi, Maxwell Casely-Hayford, Walter Fiedler, Jasmin Wellbrock, Cloe Desmet, Luigi Calzolai, Luca Varani, Steffen M. Berger, Ulrike Raap, Bernhard F. Gibbs, Elizaveta Fasler-Kan, Vadim V. Sumbayev
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Acute myeloid leukemia (AML), a blood/bone marrow cancer, is a severe and often fatal malignancy. AML cells are capable of impairing the anti-cancer activities of cytotoxic lymphoid cells. This includes the inactivation of natural killer (NK) cells a
Externí odkaz:
https://doaj.org/article/fde3b7a88f6a40a58578f302b9d89082
Autor:
Urda Rüdrich, Manuela Gehring, Eleni Papakonstantinou, Anja Illerhaus, Judith Engmann, Alexander Kapp, Karin Hartmann, N. Helge Meyer, Bernhard F. Gibbs, Ulrike Raap
Publikováno v:
Acta Dermato-Venereologica, Vol 98, Iss 8, Pp 766-771 (2018)
Bullous pemphigoid (BP) is characterized by substantial skin and blood eosinophilia as well as intensive pruritus. Since the pruritogenic cytokine interleukin (IL)-31 is increased in inflammatory skin diseases the aim of this study was to determine w
Externí odkaz:
https://doaj.org/article/8879b514222241059e0b98ead137c964
Autor:
Mikael Feracci, Jaelle N. Foot, Sushma N. Grellscheid, Marina Danilenko, Ralf Stehle, Oksana Gonchar, Hyun-Seo Kang, Caroline Dalgliesh, N. Helge Meyer, Yilei Liu, Albert Lahat, Michael Sattler, Ian C. Eperon, David J. Elliott, Cyril Dominguez
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Sam68 and T-STAR are members of the STAR family of proteins, which regulate various aspects of RNA metabolism. Here, the authors reveal structural features required for alternative splicing regulation by these proteins.
Externí odkaz:
https://doaj.org/article/b392828e149940d59b95a44e32da32fa
Autor:
Sergio Pulido, Hanna Rückert, S. Fabio Falsone, Christoph Göbl, N. Helge Meyer, Klaus Zangger
Publikováno v:
Biophysical Chemistry. 298:107040
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6204a53fd356995ec8802e22d2c723c9
https://doi.org/10.1016/j.bpc.2023.107040
https://doi.org/10.1016/j.bpc.2023.107040
Publikováno v:
MMW - Fortschritte der Medizin. 162:43-50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77605781535035eb342460319d61ef1d
https://doi.org/10.1007/s15006-020-1458-8
https://doi.org/10.1007/s15006-020-1458-8