DNA methylation of the KLK8 gene in depression symptomatology

Autor: Anders Lade Nielsen, Anders D. Børglum, Lina Bukowski, Jerry Guintivano, Ole Mors, Edwin J. C. G. van den Oord, Ana Chernomorchenko, Betina Elfving, N H Staunstrup, Per Qvist, Heidi Kaastrup Müller, Jakob Grove, Anna Starnawska, Karolina A. Aberg

Publikováno v: Starnawska, A, Bukowski, L, Chernomorchenko, A, Elfving, B, Müller, H K, van den Oord, E, Aberg, K, Guintivano, J, Grove, J, Mors, O, Børglum, A D, Nielsen, A L, Qvist, P & Staunstrup, N H 2021, ' DNA methylation of the KLK8 gene in depression symptomatology ', Clinical Epigenetics, vol. 13, no. 1, 200 . https://doi.org/10.1186/s13148-021-01184-5
Clinical Epigenetics

Background Depression is a common, complex, and debilitating mental disorder estimated to be under-diagnosed and insufficiently treated in society. Liability to depression is influenced by both genetic and environmental risk factors, which are both c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de92568f9b999575b84240c7cf45916c
https://pure.au.dk/portal/da/publications/dna-methylation-of-the-klk8-gene-in-depression-symptomatology(7cae10a5-8909-4532-858c-ed64ee650937).html

Maternal depression during pregnancy and cord blood DNA methylation: findings from the Avon Longitudinal Study of Parents and Children

Autor: A. C. Viuff, G. C. Sharp, D. Rai, T. B. Henriksen, L. H. Pedersen, K. J. Kyng, N. H. Staunstrup, A. Cortes, A. Neumann, J. F. Felix, H. Tiemeier, V. W. V. Jaddoe, C. L. Relton

Publikováno v: Translational Psychiatry, 8:244. Nature Publishing Group
Viuff, A C, Sharp, G C, Rai, D, Henriksen, T B, Pedersen, L H, Kyng, K J, Staunstrup, N H, Cortes, A, Neumann, A, Felix, J F, Tiemeier, H, Jaddoe, V W V & Relton, C L 2018, ' Maternal depression during pregnancy and cord blood DNA methylation : findings from the Avon Longitudinal Study of Parents and Children ', Translational Psychiatry, vol. 8, 244 . https://doi.org/10.1038/s41398-018-0286-4
Viuff, A-C, Sharp, G, Rai, D, Henriksen, T B, Pedersen, L H, Kyng, K J, Staunstrup, N H, Hidalgo, A P C, Neumann, A, Felix, J F, Tiemeier, H, Jaddoe, V W V & Relton, C 2018, ' Maternal depression during pregnancy and cord blood DNA methylation : Findings from the Avon Longitudinal Study of Parents and Children ', Translational Psychiatry, vol. 8, 244 . https://doi.org/10.1038/s41398-018-0286-4
Translational Psychiatry, Vol 8, Iss 1, Pp 1-10 (2018)
Translational Psychiatry

Up to 13% of women may experience symptoms of depression during pregnancy or in the postpartum period. Depression during pregnancy has been associated with an increased risk of adverse neurodevelopmental outcomes in the child and epigenetic mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8dcce008b45f03e464d173b8fadeffc4
https://pure.eur.nl/en/publications/0bfbe931-1e66-4c61-962f-3aca33708fce

CACNA1C hypermethylation is associated with bipolar disorder

Autor: Niamh L. O'Brien, Andrew McQuillin, Mette Nyegaard, Ole Mors, N H Staunstrup, Ditte Demontis, Jakob Grove, Alex Jarram, Thomas Damm Als, Anna Starnawska, Anne Hedemand, Anja E. Pen, Anders Lade Nielsen, Anders D. Børglum

Publikováno v: Translational Psychiatry
Starnawska, A, Demontis, D, Pen, A, Hedemand, A, Nielsen, A L, Staunstrup, N H, Grove, J, Als, T D, Jarram, A, O'Brien, N L, Mors, O, McQuillin, A, Børglum, A D & Nyegaard, M 2016, ' CACNA1C hypermethylation is associated with bipolar disorder ', Translational Psychiatry, vol. 6, no. 6, pp. e831 . https://doi.org/10.1038/tp.2016.99

The CACNA1C gene, encoding a subunit of the L-type voltage-gated calcium channel is one of the best-supported susceptibility genes for bipolar disorder (BD). Genome-wide association studies have identified a cluster of non-coding single-nucleotide po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e23a2713f7b4c1a2bbd2151f36d99f
https://pubmed.ncbi.nlm.nih.gov/27271857