Zobrazeno 1 - 10
of 27
pro vyhledávání: '"N H, Lubsen"'
Autor:
D Berg, B Serre, A Decha, M Penary, Thierry Levade, Bettina Couderc, Eric J. Kremer, N H Lubsen, Duboue M, François Malecaze
Publikováno v:
Gene Therapy, 13, 440-448
Gene Therapy, 13, 5, pp. 440-448
Gene Therapy, 13, 5, pp. 440-448
Posterior capsule opacification (PCO) is a common complication of cataract surgery. Using adenovirus(Ad)-mediated gene transfer, we overexpressed the proapoptotic molecules p53, procaspase 3, Bax, and TRAIL to induce therapeutic programmed cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65496ebb11494f3f885fe5239d75958
http://hdl.handle.net/2066/35533
http://hdl.handle.net/2066/35533
Autor:
M Penary, Audrey Décha, Matthias Titeux, B Serre, François Malecaze, Bettina Couderc, N H Lubsen, Arnaud Jd, Berg D, Eric J. Kremer, Duboue M
Publikováno v:
Gene Therapy, 13, 19, pp. 1422-1429
Gene Therapy, 13, 1422-1429
Gene Therapy, 13, 1422-1429
Posterior capsule opacification is the main complication of cataract surgery. Using adenovirus-mediated gene transfer, we recently reported that it was feasible to prevent PCO by overexpressing pro-apoptotic molecules such as pro-caspase 3 or Bax in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d16a319651f4c7f378f540694c8c97
https://hdl.handle.net/2066/35727
https://hdl.handle.net/2066/35727
Publikováno v:
The Journal of biological chemistry. 273(27)
The six closely related and clustered rat gamma-crystallin genes, the gammaA- to gammaF-crystallin genes, are simultaneously activated in the embryonic lens but differentially shut down during postnatal development with the gammaB-crystallin gene, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::784c371a74d9d1676b585420e276e195
https://pubmed.ncbi.nlm.nih.gov/9642290
https://pubmed.ncbi.nlm.nih.gov/9642290
Publikováno v:
Investigative ophthalmologyvisual science. 38(13)
Extralenticular expression of alpha- and beta-crystallin genes has been demonstrated in mammals and expression of gamma-crystallin genes has been shown in Xenopus laevis. To determine a possible correlation between lens determination and crystallin g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b434560d7b775b9807bc95bb0b2ebb2
https://pubmed.ncbi.nlm.nih.gov/9418729
https://pubmed.ncbi.nlm.nih.gov/9418729
Publikováno v:
The Journal of biological chemistry. 272(4)
The polymerase chain reaction was used to amplify a cDNA sequence encoding the human alphaB-crystallin. The amplified cDNA fragment was cloned into the bacterial expression vector pMAL-c2 and expressed as a soluble fusion protein coupled to maltose-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3933c1dbe5df51d5668ed6fcd8a086d
https://pubmed.ncbi.nlm.nih.gov/8999975
https://pubmed.ncbi.nlm.nih.gov/8999975
Publikováno v:
The American journal of pathology. 146(1)
We studied the expression of the angiogenic factor vascular permeability factor) (VPF, also called vascular endothelial growth factor), in human melanoma cells in vitro and in vivo. Melanoma lines that develop tumors with a low metastatic potential i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c5382b18eeb3e1213d4f2b1e6b04d2d
https://pubmed.ncbi.nlm.nih.gov/7531947
https://pubmed.ncbi.nlm.nih.gov/7531947
Autor:
A J, Pötgens, N H, Lubsen, M C, van Altena, R, Vermeulen, A, Bakker, J G, Schoenmakers, D J, Ruiter, R M, de Waal
Publikováno v:
The Journal of biological chemistry. 269(52)
Vascular permeability factor, or vascular endothelial growth factor (VPF/VEGF) is an important factor in the regulation of vascular growth and vascular permeability. VPF is a secreted, dimeric protein and has 8 cysteine residues conserved with platel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ac4070e53573e4435ee9fbd8f911703
https://pubmed.ncbi.nlm.nih.gov/7806514
https://pubmed.ncbi.nlm.nih.gov/7806514
Publikováno v:
Thrombosis and haemostasis. 71(2)
We have developed a sensitive and quantitative RT-PCR assay for the determination of tissue factor (TF) mRNA levels in human cells. An in vitro synthesized internal standard RNA was used to correct for differences in reverse transcription or amplific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da30c1a559c362213ee47750e8d9bc16
https://pubmed.ncbi.nlm.nih.gov/8191400
https://pubmed.ncbi.nlm.nih.gov/8191400
Publikováno v:
The Journal of biological chemistry. 269(2)
The bovine lens protein beta A3-crystallin has recently been shown to be an amine-donor (Lys) substrate for tissue-type transglutaminase, using a newly developed amine-acceptor hexapeptide as a probe (Groenen, P.J.T.A., Seccia, M., Smulders, R.H.P.H.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5eb610cf8526c27edce8adc68c7ba38
https://pubmed.ncbi.nlm.nih.gov/7904603
https://pubmed.ncbi.nlm.nih.gov/7904603
Publikováno v:
Journal of molecular biology. 229(4)
In duck the single copy lactate dehydrogenase B (LDH-B) gene also encodes an abundant lens protein, epsilon-crystallin. The LDH-B/epsilon-crystallin gene consists of eight exons, of which the first is non-coding. The promoter region lacks a TATA box,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6cd0c0e19da07bf37576af6f3a9e137
https://pubmed.ncbi.nlm.nih.gov/8445652
https://pubmed.ncbi.nlm.nih.gov/8445652