Zobrazeno 1 - 10
of 78
pro vyhledávání: '"N Giocanti"'
Publikováno v:
Cancer/Radiothérapie. 1:494-498
The early steps of cellular radiation response have been investigated using a linear electron accelerator operated in a split-dose mode, in such a way that the time intervals between pulse exposures to relativistic electrons ranged from fractions of
Publikováno v:
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 3(4)
Repair pathways of DNA are now better defined, and some important findings have been discovered in the last few years. DNA non-homologous end-joining (NEHJ) is a crucial process in the repair of radiation-induced double-strand breaks (DSBs). NHEJ imp
Publikováno v:
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 1(5)
The early steps of cellular radiation response have been investigated using a linear electron accelerator operated in a split-dose mode, in such a way that the time intervals between pulse exposures to relativistic electrons ranged from fractions of
Publikováno v:
Cancer research. 54(7)
Interaction between gamma-rays and camptothecin (CPT) was investigated in vitro, using log phase HeLa-S3 cells and Chinese hamster V-79 fibroblasts. A plateau of toxicity was rapidly reached for both cell lines upon exposure to CPT alone, consistent
Publikováno v:
Cancer research. 53(9)
The interactions between ionizing radiation and etoposide were probed using asynchronous growing V-79 fibroblasts. Synergistic cell kill was observed as gamma-rays were applied prior to or concomitantly with the drug. Three major determinants of enha
Publikováno v:
Cancer research. 51(12)
The cytotoxic effect of the 9-azaellipticine derivative pazelliptine in combination with gamma-ray irradiation was investigated using Chinese hamster V-79 cells in culture. gamma-ray irradiation and drug treatment (1-h drug exposure) were applied at
Autor:
N Giocanti, B Ekert
Publikováno v:
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. 31:303-319
Gamma-irrdiation of E. coli MRE 600 ribosomes in aqueous suspensions leads to covalent linkages between the RNA and some ribosomal proteins. The presence of oxygen during the irradiation strongly inhibits this phenomenon. It appears clearly that only
Autor:
N. Giocanti, B. Ekert
Publikováno v:
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. 38:63-82
SummaryIrradiation in vitro of 30S and 50S ribosomal subunits from E. coli MRE 600 by gamma rays from cobalt 60, in the absence of oxygen, results in the formation of covalent links between the RNAs and some ribosomal proteins. At low radiation doses
Publikováno v:
International journal of radiation biology and related studies in physics, chemistry, and medicine. 50(3)
The induction of RNA-protein crosslinks in E. coli 70S ribosomes by gamma-irradiation was studied by measuring the dependence of cross-link formation on ribosome concentration. The inverse dependence of cross-link percentage upon concentration up to
Autor:
N. Giocanti, B. Ekert
Publikováno v:
International journal of radiation biology and related studies in physics, chemistry, and medicine. 40(5)
In the absence of oxygen, gamma-irradiation produces covalent links between some ribosomal proteins and 16 S RNA to 23 S RNA, within 70 S ribosomes from E. coli MRE600. Under optimal conditions minimizing the structural modifications induced by radia