Zobrazeno 1 - 10
of 60
pro vyhledávání: '"N G Bowery"'
Autor:
Trevor G. Smart, N G Bowery
Publikováno v:
British Journal of Pharmacology. 147:S109-S119
gamma-Aminobutyric acid (GABA) emerged as a potentially important brain chemical just over 50 years ago, but its significance as a neurotransmitter was not fully realized until over 16 years later. We now know that at least 40% of inhibitory synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6b6fc435c83835cb550f0a3e2adcf5b
https://doi.org/10.1038/sj.bjp.0706443
https://doi.org/10.1038/sj.bjp.0706443
Publikováno v:
Phytotherapy Research. 14:24-29
A number of plant species used in traditional medicine for the relief of pain have been selected from the medicinal and scientific literature of China, South America, Asia and West Africa. Extracts were prepared and tested in three in vitro receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f1f7f028a75bab2122ddf1568c834d7
https://doi.org/10.1002/(sici)1099-1573(200002)14:1<24::aid-ptr537>3.0.co
https://doi.org/10.1002/(sici)1099-1573(200002)14:1<24::aid-ptr537>3.0.co
Autor:
N G, Bowery
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 58
This chapter forms an introduction to the subsequent chapters in this volume which highlight the significance and potential therapeutic application of GABA(B) receptors. It is now 30 years since the GABA(B) site was first described in mammalian tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7900bfcad1224986e8fd0989ebfa1151
https://pubmed.ncbi.nlm.nih.gov/20655476
https://pubmed.ncbi.nlm.nih.gov/20655476
Publikováno v:
British journal of pharmacology. 136(2)
1. The modulatory effects of mGlu receptors on NMDA-induced potential changes in spinal motoneurones were studied in vitro. 2. Selective activation of mGlu5 receptors by 10 microM (RS)-2-Chloro-5-hydroxyphenylglycine (CHPG; EC(50)=280 +/- 24 microM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd3bd54d67eeb80dd5c1451b2b4acfc1
https://pubmed.ncbi.nlm.nih.gov/12010773
https://pubmed.ncbi.nlm.nih.gov/12010773
Publikováno v:
British journal of pharmacology. 132(2)
1. Metabotropic gamma-aminobutyric acid receptors (GABA(B)) exist both pre- and postsynaptically throughout the brain, mediating the suppression of neurotransmitter release and late inhibitory postsynaptic potentials. Investigation of GABA(B) recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4309ee42d1572ba848897018428b284
https://pubmed.ncbi.nlm.nih.gov/11159697
https://pubmed.ncbi.nlm.nih.gov/11159697
Autor:
N. G. Bowery
Publikováno v:
Pharmacology of GABA and Glycine Neurotransmission ISBN: 9783642631917
Glutamate and GABA Receptors and Transporters ISBN: 9780748408818
Glutamate and GABA Receptors and Transporters ISBN: 9780748408818
It is now about 20 years since we first examined the Cl−-dependent action of GABA on peripheral neurones and, in particular, on nerve terminals of sympathetic fibres. At the time we were trying to mimic the established depolarizing action on presyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369cc6b528b73e8a6d2e18b1da163068
https://doi.org/10.1007/978-3-642-56833-6_12
https://doi.org/10.1007/978-3-642-56833-6_12
Autor:
S, Towers, A, Princivalle, A, Billinton, M, Edmunds, B, Bettler, L, Urban, J, Castro-Lopes, N G, Bowery
Publikováno v:
The European journal of neuroscience. 12(9)
The presence of metabotropic receptors for GABA, GABAB, on primary afferent terminals in mammalian spinal cord has been previously reported. In this study we provide further evidence to support this in the rat and show that the GABAB receptor subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74680593d19c3af0118365a539369a52
https://pubmed.ncbi.nlm.nih.gov/10998104
https://pubmed.ncbi.nlm.nih.gov/10998104
Publikováno v:
Phytotherapy research : PTR. 14(1)
A number of plant species used in traditional medicine for the relief of pain have been selected from the medicinal and scientific literature of China, South America, Asia and West Africa. Extracts were prepared and tested in three in vitro receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c01729d463f4bad04ca5d43b9e5b554b
https://pubmed.ncbi.nlm.nih.gov/10641043
https://pubmed.ncbi.nlm.nih.gov/10641043
Autor:
M J, Koepp, K S, Hand, C, Labbé, M P, Richardson, W, Van Paesschen, V H, Baird, V J, Cunningham, N G, Bowery, D J, Brooks, J S, Duncan
Publikováno v:
Annals of neurology. 43(5)
By using [11C]flumazenil-positron emission tomography ([11C]FMZ-PET), we have previously shown that reductions of central benzodiazepine receptors (cBZRs) are restricted to the hippocampus in mesial temporal lobe epilepsy (mTLE) caused by unilateral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11294eb050dea935789b9881d1edc5d1
https://pubmed.ncbi.nlm.nih.gov/9585356
https://pubmed.ncbi.nlm.nih.gov/9585356
Publikováno v:
British journal of pharmacology. 120(7)
1. The distribution and some pharmacological properties of centrally located dextromethorphan high-affinity binding sites were investigated by in vitro autoradiography. 2. Sodium chloride (50 mM) induced a 7 to 12 fold increase in dextromethorphan bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44c5ed7bb584c4c2fe8524c1e1136b64
https://pubmed.ncbi.nlm.nih.gov/9105700
https://pubmed.ncbi.nlm.nih.gov/9105700