Zobrazeno 1 - 10 of 17 pro vyhledávání: '"N G, Dolinnaia"'
1
[Chemical cleavage of DNA with single base mismatches for detection of mutations of unknown localization]
Autor: A A, Neschastnova, V K, Gasanova, G A, Belitskiĭ, M G, Iakubovskaia, N G, Dolinnaia
Publikováno v: Molekuliarnaia biologiia. 41(3)
The most promising approach for detection of random point mutations relies upon the DNA chemical cleavage near associated mismatching base pairs. In our study, the series of heteroduplexes with all types of mismatches and extrahelical nucleotide resi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55d5bdf71a1285aeb6605a96e22c0180
https://pubmed.ncbi.nlm.nih.gov/17685231
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3
[Chemical ligation and recombination of DNA fragments by formation (exchange) of disulfide bonds, located in the sugar-phosphate backbone]
Autor: N G, Dolinnaia, V G, Metelev
Publikováno v: Bioorganicheskaia khimiia. 26(4)
Effective methods of the directed introduction of diphosphoryl disulfide bridges into hairpin DNA duplexes in place of natural phosphodiester groups were developed using the H2O2-effected ligation of 3'- and 5'-thiophosphorylated oligonucleotides or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afa1377b0da10680901065fa763f475e
https://pubmed.ncbi.nlm.nih.gov/10857023
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7
[Synthesis of cyclic oligodeoxyribonucleotides with non-nucleotide inserts]
Autor: T S, Oretskaia, N G, Dolinnaia, I N, Merenkova, N F, Krynetskaia, E A, Romanova, E M, Volkov, M, Blumenfeld, M, Vasseur, Z A, Shabarova
Publikováno v: Bioorganicheskaia khimiia. 20(1)
An effective method for the oligonucleotide cyclization using BrCN-induced chemical ligation was developed. The novel idea to incorporate non-nucleotide inserts makes the process of cyclizations independent of the inner secondary structure of the lin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bbac513636a432198f4e0a28aeceab2
https://pubmed.ncbi.nlm.nih.gov/8161364
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8
[Chemical reactions in double-helical nucleic acids. XIV. Effectiveness of forming phosphodiester bonds between various nucleotide units]
Autor: I P, Merenkova, N G, Dolinnaia, T S, Oretskaia, N I, Sokolova, Z A, Shabarova
Publikováno v: Bioorganicheskaia khimiia. 18(1)
Efficiency of the template-directed condensation of oligonucleotides depends on the nature of the nucleotide units to be joined. Fourteen out of sixteen dinucleotide combinations in double-stranded DNA were examined. Alterations of the reaction effic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a87b784e7536c94472a02749a85d7adc
https://pubmed.ncbi.nlm.nih.gov/1524587
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9
[Chemical reactions in double-helical nucleic acids. X. Kinetics of oligomer condensation under the effect of synthetic water-soluble carbodiimides]
Autor: N G, Dolinnaia, A V, Tsytovich, V N, Sergeev, M N, Gertsiuk, Z A, Shabarova
Publikováno v: Bioorganicheskaia khimiia. 16(9)
Chemical ligation of oligonucleotides in double stranded complexes has been considered in its structural-kinetic aspect. In a study of the reactivity of eleven synthetic water soluble carbodiimides the reaction rate has been found to be strongly affe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::18d818ccef7aedae04d8202e1001d835
https://pubmed.ncbi.nlm.nih.gov/2080926
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10
[Chemical reactions of double-helical nucleic acids. XI. Interaction between kinetic parameters of chemical ligation in modified DNA-duplexes and structure of the reaction site]
Autor: N G, Dolinnaia, A V, Tsytovich, S G, Tevosian, V N, Sergeev, Z A, Shabarova
Publikováno v: Bioorganicheskaia khimiia. 16(9)
To characterize structural factors affecting kinetic parameters of chemical ligation, DNA duplexes with various arrangements of reacting groups in the ligation site have been synthesized and studied. The modifications included replacement of a deoxyt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e8a2f4c4262c9460c08616d07411853
https://pubmed.ncbi.nlm.nih.gov/2080927
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