Zobrazeno 1 - 10
of 60
pro vyhledávání: '"N F, Hacker"'
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/b266964d582c4f589faa7404fa0ef34b
Autor:
C, van Haaften-Day, Y, Shen, F, Xu, Y, Yu, A, Berchuck, L J, Havrilesky, H W, de Bruijn, A G, van der Zee, R C, Bast, N F, Hacker
Publikováno v:
Cancer. 92(11)
Ovarian carcinoma remains the leading cause of death from gynecologic malignancy in Australia, the Netherlands, and the United States. CA-125-II, the most widely used serum marker, has limited sensitivity and specificity for detecting small-volume, e
Publikováno v:
Cancer. 91(8)
The role of adjuvant therapy in the management of patients with malignant mixed Müllerian tumors (MMMT) of the uterus has not been defined. The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed.A pi
Publikováno v:
International journal of cancer. 88(4)
Over-expression of epidermal growth factor receptor (EGFR) in ovarian cancer has been well documented. Human NIH:OVCAR-8 ovarian carcinoma cells were transfected with an expression vector containing the anti-sense orientation of truncated human EGFR
Publikováno v:
Cancer. 89(2)
Effective combination chemotherapy has improved the previously dismal prognosis for malignant ovarian germ cell tumors (MOGCT) dramatically. In young patients, conservative surgery with adjuvant chemotherapy has made the preservation of fertility pos
Publikováno v:
Seminars in surgical oncology. 19(1)
Epithelial carcinoma of the ovary is the most lethal of gynaecological malignancies and it affects about one in 70 women in developed countries. Over 75% of women with the disease have tumour spread beyond the pelvis at the time of diagnosis, and the
Publikováno v:
Cancer. 86(10)
After radical hysterectomy and pelvic lymph node dissection, an identifiable subgroup of patients with International Federation of Gynecology and Obstetrics Stage IB lymph node negative cervix carcinoma remains at high risk of pelvic recurrence. This
Autor:
N F, Hacker
Publikováno v:
Annals of the Academy of Medicine, Singapore. 27(5)
In recent years, vulvar cancer management has been revolutionised with a more conservative approach being recommended for the primary lesion, and a more rational approach to the management of the lymph nodes. Treatment has become individualised with
Autor:
C, van Haaften-Day, P, Russell, C M, Boyer, B J, Kerns, J R, Wiener, D N, Jensen, R C, Bast, N F, Hacker
Publikováno v:
Cancer. 77(10)
Tumors of borderline malignancy are still a controversial subgroup of ovarian neoplasms. The expression of several cell regulatory proteins was studied to characterize the molecular phenotype of these tumors, and to compare them with their benign and
Autor:
J, van der Velden, N F, Hacker
Publikováno v:
Current opinion in obstetricsgynecology. 8(1)
Basic research in vulvar cancer results in new prognostic variables such as human papillomavirus DNA and epidermal growth factor receptor level. It also suggests that p53 mutants are involved in the pathogenesis of this disease. However, histopatholo