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Akademický článek

Apocynin Prevents Cigarette Smoke-Induced Anxiety-Like Behavior and Preserves Microglial Profiles in Male Mice

Autor: Rana Alateeq, Alina Akhtar, Simone N. De Luca, Stanley M. H. Chan, Ross Vlahos

Publikováno v: Antioxidants, Vol 13, Iss 7, p 855 (2024)

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally and is primarily caused by cigarette smoking (CS). Neurocognitive comorbidities such as anxiety and cognitive impairments are common among people with COPD. CS-

Externí odkaz: https://doaj.org/article/3aaef7fe3a224563bb44e5286f93a508

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Akademický článek

Ebselen prevents cigarette smoke-induced cognitive dysfunction in mice by preserving hippocampal synaptophysin expression

Autor: Simone N. De Luca, Kurt Brassington, Stanley M. H. Chan, Aleksandar Dobric, Kevin Mou, Huei Jiunn Seow, Ross Vlahos

Publikováno v: Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)

Abstract Background Cigarette smoking (CS) is the leading cause of chronic obstructive pulmonary disease (COPD). The “spill-over” of pulmonary inflammation into the systemic circulation may damage the brain, leading to cognitive dysfunction. Cess

Externí odkaz: https://doaj.org/article/3e7a027d1718470fbcfc5197f3e05db8

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Commento all'art. 11 (Principi di revisione), in La revisione legale dei conti annuali e dei conti consolidati (d. lgs. 27 gennaio 2010, n. 39), Commentario a cura di N. de Luca

Autor: Strampelli, Giovanni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4050::ebcdb64de4b910a54af29d36c16fe2bf
http://hdl.handle.net/11565/3718454

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Akademický článek

Cigarette Smoke Exposure Induces Neurocognitive Impairments and Neuropathological Changes in the Hippocampus

Autor: Aleksandar Dobric, Simone N. De Luca, Huei Jiunn Seow, Hao Wang, Kurt Brassington, Stanley M. H. Chan, Kevin Mou, Jonathan Erlich, Stella Liong, Stavros Selemidis, Sarah J. Spencer, Steven Bozinovski, Ross Vlahos

Publikováno v: Frontiers in Molecular Neuroscience, Vol 15 (2022)

Background and ObjectiveNeurocognitive dysfunction is present in up to ∼61% of people with chronic obstructive pulmonary disease (COPD), with symptoms including learning and memory deficiencies, negatively impacting the quality of life of these ind

Externí odkaz: https://doaj.org/article/a877ab5c1eb34adcb041374018a5eb00

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Akademický článek

Influenza A Virus-Driven Airway Inflammation may be Dissociated From Limb Muscle Atrophy in Cigarette Smoke-Exposed Mice

Autor: Kevin Mou, Stanley M. H. Chan, Kurt Brassington, Aleksandar Dobric, Simone N. De Luca, Huei Jiunn Seow, Stavros Selemidis, Steven Bozinovski, Ross Vlahos

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Limb muscle dysfunction is a hallmark of Chronic Obstructive Pulmonary Disease (COPD) which is further worsened following a viral-induced acute exacerbation of COPD (AECOPD). An amplified airway inflammation underlies the aggravated respiratory sympt

Externí odkaz: https://doaj.org/article/7be818b25e384a6582b627fb213a38cc

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Akademický článek

Glial remodeling enhances short-term memory performance in Wistar rats

Autor: Simone N. De Luca, Alita Soch, Luba Sominsky, Thai-Xinh Nguyen, Abdulhameed Bosakhar, Sarah J. Spencer

Publikováno v: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)

Abstract Background Microglia play a key role in neuronal circuit and synaptic maturation in the developing brain. In the healthy adult, however, their role is less clear: microglial hyperactivation in adults can be detrimental to memory due to exces

Externí odkaz: https://doaj.org/article/915d67117c6c4bedbe4c3e67f72f056c

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Periodical

p75NTR gene and suicide attempts in young adults with a history of childhood‐onset mood disorderPlease cite this article as follows: McGregor S, Strauss J, Bulgin N, De Luca V, George CJ, Kovacs M, Kennedy JL. 2007. p75NTR Gene and Suicide Attempts in Young Adults With a History of Childhood‐Onset Mood Disorder. Am J Med Genet Part B 144B:696–700.S. McGregor and J. Strauss contributed equally to this manuscript.

Autor: McGregor, S., Strauss, J., Bulgin, N., De Luca, V., George, C.J., Kovacs, M., Kennedy, J.L.

Publikováno v: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics; July 2007, Vol. 144 Issue: 5 p696-700, 5p

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Cigarette smoke-induced pulmonary impairment is associated with social recognition memory impairments and alterations in microglial profiles within the suprachiasmatic nucleus of the hypothalamus

Autor: Simone N. De Luca, Stanley M.H. Chan, Aleksandar Dobric, Hao Wang, Huei Jiunn Seow, Kurt Brassington, Kevin Mou, Rana Alateeq, Alina Akhtar, Steven Bozinovski, Ross Vlahos

Publikováno v: Brain, Behavior, and Immunity. 109:292-307

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d67cee50c861c15566121617315e3e28
https://doi.org/10.1016/j.bbi.2023.02.005

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Ginsenosides enhance P2X7-dependent cytokine secretion from LPS-primed rodent macrophages

Autor: Kshitija Dhuna, Ray Helliwell, Simone N. De Luca, Sarah J. Spencer, Leanne Stokes

Publikováno v: Purinergic Signalling.

The activation of P2X7 is a well-known stimulus for the NLRP3-caspase 1 inflammasome and subsequent rapid IL-1β secretion from monocytes and macrophages. Here we show that positive allosteric modulators of P2X7, ginsenosides, can enhance the release

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a06cc3d170d21db0a2e9e82c69e5b4
https://doi.org/10.1007/s11302-023-09935-0

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