Zobrazeno 1 - 10
of 11
pro vyhledávání: '"N D, Igumnova"'
Publikováno v:
Biokhimiia (Moscow, Russia). 55(5)
It was shown that the ability of sheep and horse haptoglobins differing in their immunological properties to inhibit PGH synthetase is about the same. It was found that haptoglobin inhibits the PGH synthetase-catalyzed enzymatic reaction, the inhibit
Publikováno v:
Farmakologiia i toksikologiia. 53(2)
Benzofurocaine similarly to ortophen (voltaren) causes dose-dependent suppression of acute inflammatory reactions induced in rats by carragheenin, serotonin and histamine, protects animals from absolutely lethal dose of cellulose sulphate. When admin
Autor:
I. I. Bityukova, V. M. Solov'ev, D. A. Kharkevich, N. V. Klimova, N. D. Igumnova, A. P. Skoldinov
Publikováno v:
Pharmaceutical Chemistry Journal. 22:452-456
In connection with the existence of common features in the structures of the active sites of choline receptors and acetylcholinesterase (ACE), there is considerable interest in elucidating how the hydrophobicity of the radicals attached to the quater
Publikováno v:
Biokhimiia (Moscow, Russia). 40(1)
It is shown that effect of alcohols ROH on the hydrolysis of butyryl-choline and acetylcholine by choline esterase (E. C. 3.1.1.8) is complex; it included the concurrent and the unconcurrent inhibitions, the interaction with the acylenzyme to form mo
Publikováno v:
Farmakologiia i toksikologiia. 46(5)
A study was made of the character and kinetics of interaction of acetylsalicylic acid and indomethacin with endoperoxide prostaglandin synthetase (PGH-synthetase) of sheep vesicular glands and human platelets. Enzymatic activity of PGH-synthetase was
Publikováno v:
Biokhimiia (Moscow, Russia). 40(5)
Butanol-1 and butandiol-1,4 are shown to increase the decarbamoylation rate of N-methylcarbamoyl- and N,N-dimethylcarbamoyl-cholinesterase. It is mainly due to the formation of a ternary complex NEA which is decomposed in 2,5 times faster than corbam
Autor:
A. P. Skoldinov, D. A. Kharkevich, N. V. Klimova, I. I. Bityukova, N. D. Igumnova, V. M. Solov'ev
Publikováno v:
ChemInform. 19
Publikováno v:
Farmakologiia i toksikologiia. 50(1)
A combined effect on the irreversible inhibitor aspirin and fast reversible inhibitors ibuprofen, naproxen and sodium salicylate on prostaglandin-H-synthetase was studied on microsomal fractions from ram vesicular glands. The fast reversible inhibito
Publikováno v:
Farmakologiia i toksikologiia. 52(2)
The kinetics of enzymatic cholinesterase hydrolysis of dicarboxylic acid esters with neuromuscular blocking activity was studied in vitro. The maximum hydrolysis rate was shown to increase on elongation of the distance between ester groups both in th
Publikováno v:
Farmakologiia i toksikologiia. 47(1)
The authors studied the pattern and mechanism of ibuprophen and naproxen interaction with endoperoxideprostaglandin synthetase (PGH synthetase) of sheep vesicular glands. The enzymatic activity of PGH synthetase was determined polarographically with