Zobrazeno 1 - 10
of 54
pro vyhledávání: '"N D, Christofides"'
Autor:
John E.M. Midgley, N D Christofides
Publikováno v:
Clinical Chemistry. 55:439-441
In the history of clinical immunoassay, even up to the present day, no group of tests has been subjected to more scrutiny and controversy than analog-type free-analyte assays (1)(2)(3)(4). Unfortunately, inappropriate design of many experiments has l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ef4ac8fc1915e6abaf527dee0520ef
https://doi.org/10.1373/clinchem.2008.116525
https://doi.org/10.1373/clinchem.2008.116525
Autor:
C P Sheehan, N D Christofides
Publikováno v:
Clinical Chemistry. 41:17-23
We describe the development and validation of a one-step nonradioactive immunoassay for free thyroxine (Amerlite-MAB FT4) in serum or plasma, in the dedicated Amerlite enhanced luminescence assay system. A monoclonal antibody to thyroxine (T4), conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93d463844db8ebc1c405666f18ff3f52
https://doi.org/10.1093/clinchem/41.1.17
https://doi.org/10.1093/clinchem/41.1.17
Autor:
N D Christofides, C P Sheehan
Publikováno v:
Clinical Chemistry. 41:24-31
The technical and diagnostic performance of the Amerlite-MAB enhanced luminescence assay for free thyroxine (FT4) was assessed in a multicenter evaluation trial. The euthyroid central 95% reference range for FT4 (1393 subjects) was 11.5-27.7 pmol/L (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2339ec07fb8412a530df5b498142c6
https://doi.org/10.1093/clinchem/41.1.24
https://doi.org/10.1093/clinchem/41.1.24
One-Step, Labeled-Antibody Assay for Measuring Free Thyroxin. II. Performance in a Multicenter Trial
Autor:
C P Sheehan, N D Christofides
Publikováno v:
Clinical Chemistry. 38:19-25
The technical and diagnostic performance of a labeled antibody radioassay for free thyroxin (Amerlex-MAB* FT4) was examined in a multicenter trial. The overall mean within-assay precision (CV) in eight centers was 6.2% at 30 pmol/L and 3.6% at 13 pmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f921245bb281086c776afa313f061da1
https://doi.org/10.1093/clinchem/38.1.19
https://doi.org/10.1093/clinchem/38.1.19
Publikováno v:
Clinical Chemistry. 38:11-18
We describe a one-step, labeled-antibody radioassay for measuring free thyroxin (FT4) in serum or plasma, based on a novel principle. FT4 in the sample competes with a gross molar excess (over antibody) of a cross-reactant (L-triiodothyronine, T3), c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd18f9b1417a7fe6dc47a187b148575
https://doi.org/10.1093/clinchem/38.1.11
https://doi.org/10.1093/clinchem/38.1.11
Publikováno v:
Clinical Chemistry. 36:765-771
Free thyroxin (FT4) estimates by two immunoassays were compared with the concentrations of albumin in serum of apparently euthyroid subjects who either were (n = 99) or were not (n = 327) suffering from severe nonthyroidal illness (sNTI). In neither
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4361a87cd790cf29e4c6976d2494a21f
https://doi.org/10.1093/clinchem/36.5.765
https://doi.org/10.1093/clinchem/36.5.765
Autor:
N D Christofides, John E.M. Midgley
Publikováno v:
Clinical Chemistry. 55:2228-2229
We have read with interest recent reports of the measurement of free thyroxine and free triiodothyronine by ultrafiltration and tandem mass spectrometry (1)(2)(3)(4). There is, however, a fundamental flaw in these studies that we wish to bring to gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c384875ce7175072c3d0d2953d403e2
https://doi.org/10.1373/clinchem.2009.134593
https://doi.org/10.1373/clinchem.2009.134593
Publikováno v:
Clinical chemistry. 45(4)
Free thyroxine (FT4) assays may exhibit biases that are related to serum T4 binding capacity (sBC). We describe two tests that can be used to assess the presence and magnitude of sBC-dependent biases in FT4 assays.We used a direct equilibrium dialysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54f2e081e95c74e026f62b8e43dc4863
https://pubmed.ncbi.nlm.nih.gov/10102912
https://pubmed.ncbi.nlm.nih.gov/10102912
Autor:
N D, Christofides, C P, Sheehan
Publikováno v:
Clinical chemistry. 41(1)
We describe the development and validation of a one-step nonradioactive immunoassay for free thyroxine (Amerlite-MAB FT4) in serum or plasma, in the dedicated Amerlite enhanced luminescence assay system. A monoclonal antibody to thyroxine (T4), conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::644cd49facce4692c15b24a4efe47317
https://pubmed.ncbi.nlm.nih.gov/7813074
https://pubmed.ncbi.nlm.nih.gov/7813074
Autor:
N D, Christofides, C P, Sheehan
Publikováno v:
Clinical chemistry. 41(1)
The technical and diagnostic performance of the Amerlite-MAB enhanced luminescence assay for free thyroxine (FT4) was assessed in a multicenter evaluation trial. The euthyroid central 95% reference range for FT4 (1393 subjects) was 11.5-27.7 pmol/L (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d4c8cbf65a8e730b07a332d4fbf5330
https://pubmed.ncbi.nlm.nih.gov/7813077
https://pubmed.ncbi.nlm.nih.gov/7813077