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Autor:
N C Ramer, C. W. Hanson, R N Swanson, P B Fernandes, Dwight J. Hardy, J J Clement, Nathan L. Shipkowitz
Publikováno v:
Antimicrobial Agents and Chemotherapy. 35:1108-1111
Tiacumicins B and C are members of a novel group of 18-membered macrolide antibiotics with in vitro activity against Clostridium difficile. The MICs against 15 strains of C. difficile were 0.12 to 0.25 microgram/ml for tiacumicin B, 0.25 to 1 microgr