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pro vyhledávání: '"N C, Margaretten"'
Publikováno v:
Toxicology and applied pharmacology. 87(1)
Human peripheral blood mononuclear cells (PBMC) were isolated from healthy volunteers and exposed in vitro to phenytoin or carbamazepine, two widely used antiepileptic drugs (AED). This study investigated the effects of these drugs on natural killer
Autor:
N. C. Margaretten, R. P. Warren
Publikováno v:
Epilepsia. 28(1)
An animal model was used to study the effects of phenytoin on immune function. Inbred NFS mice, injected with phenytoin, 10-40 mg/kg, and immunized with bovine serum albumin (BSA), demonstrated a dose-dependent decrease in production of IgG antibodie
Autor:
N C, Margaretten, H, Witschi
Publikováno v:
Cancer research. 48(10)
Suspensions of an oxygen-sensitive (MT-7) and of an oxygen-insensitive(M109) tumor cell line were injected i.v. into BALB/c mice. Exposure to 100% O2 after injection of the cells did not modify the initial arrest of either cell line in the lung. Expo