Zobrazeno 1 - 10
of 15
pro vyhledávání: '"N C, Inestrosa"'
Publikováno v:
Biochemical and Biophysical Research Communications. 213:96-103
The main component of Alzheimer's disease (AD) amyloid deposits is amyloid beta-peptide (A beta), a fragment of the larger amyloid precursor protein (APP). The cellular source of A beta is not known, but a circulatory origin has been postulated. We s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c503632e64c2a2bd5f7b1977ab320ce
https://doi.org/10.1006/bbrc.1995.2103
https://doi.org/10.1006/bbrc.1995.2103
Publikováno v:
Journal of neuroscience research. 60(3)
Low density lipoprotein receptor-related protein (LRP) participates in the uptake and degradation of several ligands implicated in neuronal pathophysiology including apolipoprotein E (apoE), activated alpha(2) -macroglobulin (alpha(2)M*) and beta-amy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8a577836a7801db1dcdb544372f336c
https://pubmed.ncbi.nlm.nih.gov/10797543
https://pubmed.ncbi.nlm.nih.gov/10797543
Publikováno v:
Journal of neuroscience research. 58(3)
We studied the expression of the mannose receptor (ManR) in rat microglial cells. Microglial cells are the central nervous system resident macrophages, key participants of the innate immune response. ManR is a differentiation marker and a relevant gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cf7eedb4875e3f0ceed733852c80031
https://pubmed.ncbi.nlm.nih.gov/10518112
https://pubmed.ncbi.nlm.nih.gov/10518112
Publikováno v:
Journal of neuroscience research. 56(6)
This work addresses the differential effects of several oxidative insults on two neuronal cell lines, PC12 and Neuro 2a cells, extensively used as neuronal models in vitro. We measured cellular damage using the cytotoxic assays for MTT reduction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::718c09fc5963a9c6ba7cbb0e17429193
https://pubmed.ncbi.nlm.nih.gov/10374817
https://pubmed.ncbi.nlm.nih.gov/10374817
Publikováno v:
Neurochemical research. 23(2)
It has been suggested that acetylcholinesterase (AChE) has both a putative proteolytic activity against the amyloid precursor protein (APP), and a capacity to accelerate the assembly of amyloid-beta-peptide (Abeta) into Alzheimer's fibrils. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::523c637043df6fcd099b33e3caba27c7
https://pubmed.ncbi.nlm.nih.gov/9475506
https://pubmed.ncbi.nlm.nih.gov/9475506
Publikováno v:
Journal of molecular biology. 272(3)
Acetylcholinesterase (AChE), an enzyme involved in the hydrolysis of the neurotransmitter acetylcholine, consistently colocalizes with the amyloid deposits characteristic of Alzheimer's disease and may contribute to the generation of amyloid proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::540a4720c42c7e118e2d737912657b16
https://pubmed.ncbi.nlm.nih.gov/9325095
https://pubmed.ncbi.nlm.nih.gov/9325095
Publikováno v:
Journal of cellular physiology. 166(2)
We have studied the influence of the extracellular matrix (ECM) on the amount of beta-amyloid precursor protein (APP) and C-terminal amyloid-bearing fragments in 313 fibroblasts. After incubation with ECM components, the cellular APP content of 3T3 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72dc50ae40dbf62171d35e866600a8a8
https://pubmed.ncbi.nlm.nih.gov/8591996
https://pubmed.ncbi.nlm.nih.gov/8591996
Autor:
N C, Inestrosa, C, Soto
Publikováno v:
Biological research. 25(2)
Alzheimer's disease is a progressive neurodegenerative disorder that affects a significant percentage of elderly individuals. Degenerative nerve cells express atypical proteins, and amyloid is deposited. The hallmark event of Alzheimer's disease is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c668a45494a088cdfb7ad807c2b22a90
https://pubmed.ncbi.nlm.nih.gov/1365703
https://pubmed.ncbi.nlm.nih.gov/1365703
Autor:
N C, Inestrosa, R, Labarca, A, Perelman, E O, Campos, R, Araneda, M, González, E, Brandan, J P, Sánchez, R, González-Plaza
Publikováno v:
Archivos de biologia y medicina experimentales. 23(2)
The biology of planktotrophic larvae of Concholepas concholepas is the main bottleneck towards developing biotechnologies to rear this muricid. Data concerning planktonic larvae development, diets and environmental signals triggering larval settlemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0de3e99239c5ead518cf8cdbedf6f12a
https://pubmed.ncbi.nlm.nih.gov/1966831
https://pubmed.ncbi.nlm.nih.gov/1966831
Publikováno v:
The Journal of biological chemistry. 265(1)
Rat liver cholinesterases were found to share properties and characteristics with those expressed in cholinergic tissues. The distribution and presence of different molecular forms of cholinesterases in different subcellular organelles of rat liver w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22f1960d5c6ea4c164052b56b534ccba
https://pubmed.ncbi.nlm.nih.gov/2152920
https://pubmed.ncbi.nlm.nih.gov/2152920