Characterization of the caspase inhibitor IDN-1965 in a model of apoptosis-associated liver injury

Autor: N C, Hoglen, B P, Hirakawa, C D, Fisher, S, Weeks, A, Srinivasan, A M, Wong, K L, Valentino, K J, Tomaselli, X, Bai, D S, Karanewsky, P C, Contreras

Publikováno v: The Journal of pharmacology and experimental therapeutics. 297(2)

Previous studies have shown that caspase inhibitors are effective at protecting against anti-Fas antibody (alpha-Fas)-mediated liver injury/lethality. The purpose of these experiments was to characterize more fully the efficacy of a broad-spectrum, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21519d71b2bc60bf89aeed885bfe722f
https://pubmed.ncbi.nlm.nih.gov/11303074

3,3',4,4'-Tetrabromobiphenyl sensitizes rats to the hepatotoxic effects of endotoxin by a mechanism that involves more than tumor necrosis factor

Autor: S I, Shedlofsky, N C, Hoglen, L E, Rodman, R, Honchel, F R, Robinson, A T, Swim, C J, McClain, L W, Robertson

Publikováno v: Hepatology (Baltimore, Md.). 14(6)

To determine whether the cytokine tumor necrosis factor/cachectin might be a mediator of hepatotoxicity seen after exposure to polyhalogenated aromatic hydrocarbons, rats treated with a single dose of 3,3',4,4'-tetrabromobiphenyl (150 mumol/kg intrap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e9c84c11eea521d6b616272b14edae8
https://pubmed.ncbi.nlm.nih.gov/1660020

Total Synthesis of ( R,R,R)-γ-Tocopherol through Cu-Catalyzed Asymmetric 1,2-Addition.

Autor: Wu, Zhongtao¹, Harutyunyan, Syuzanna R.¹, Minnaard, Adriaan J.¹ a.j.minnaard@rug.nl

Publikováno v: Chemistry - A European Journal. Oct2014, Vol. 20 Issue 44, p14250-14255. 6p.

Azetidines of pharmacological interest.

Autor: Parmar DR; Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Sirohi, Rajasthan, India.; Piramal Pharma Limited-Discovery Solutions, Ahmedabad, Gujarat, India., Soni JY; Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Sirohi, Rajasthan, India., Guduru R; Piramal Pharma Limited-Discovery Solutions, Ahmedabad, Gujarat, India., Rayani RH; Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Sirohi, Rajasthan, India.; Piramal Pharma Limited-Discovery Solutions, Ahmedabad, Gujarat, India., Kusurkar RV; Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Sirohi, Rajasthan, India.; Piramal Pharma Limited-Discovery Solutions, Ahmedabad, Gujarat, India., Vala AG; Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Sirohi, Rajasthan, India.; Piramal Pharma Limited-Discovery Solutions, Ahmedabad, Gujarat, India.

Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2021 Nov; Vol. 354 (11), pp. e2100062. Date of Electronic Publication: 2021 Jun 29.

Hepatoprotective effect of methylsulfonylmethane against carbon tetrachloride-induced acute liver injury in rats.

Autor: Kamel, Rehab, El Morsy, Engy

Publikováno v: Archives of Pharmacal Research; Sep2013, Vol. 36 Issue 9, p1140-1148, 9p