Zobrazeno 1 - 10
of 764
pro vyhledávání: '"N Bryan"'
Publikováno v:
European Cells & Materials, Vol 24, Pp 249-265 (2012)
Wound healing requires a fine balance between the positive and deleterious effects of reactive oxygen species (ROS); a group of extremely potent molecules, rate limiting in successful tissue regeneration. A balanced ROS response will debride and disi
Externí odkaz:
https://doaj.org/article/48cd4a1597db4291a89d4b7336c4dc0d
Autor:
My H. Hoang, Zachary L. Skidmore, Hans Rindt, Shirley Chu, Bryan Fisk, Jennifer A. Foltz, Catrina Fronick, Robert Fulton, Mingyi Zhou, Nathan J. Bivens, Carol N. Reinero, Todd A. Fehniger, Malachi Griffith, Jeffrey N. Bryan, Obi L. Griffith
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Spontaneous cancers in companion dogs are robust models of human disease. Tracking tumor-specific immune responses in these models requires reagents to perform species-specific single cell T cell receptor sequencing (scTCRseq). scTCRseq and
Externí odkaz:
https://doaj.org/article/5c2e989e11084889b89031b8e7093906
Autor:
Carissa J. Norquest, Anita Rogic, Phyllis A. Gimotty, Charles A. Maitz, Hansjorg Rindt, Hayley L. Ashworth, Jeffrey N. Bryan, Lindsay L. Donnelly, Angela L. McCleary-Wheeler, Brian K. Flesner
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionZoledronic acid (ZOL) is a third-generation bisphosphonate with a higher affinity for bone resorption areas than earlier bisphosphonates (i.e., pamidronate, PAM). In human medicine, ZOL provides improved bone pain relief and prolonged tim
Externí odkaz:
https://doaj.org/article/bde0331aac46404291b83e663e3169b2
Autor:
Biao Ruan, Yanan He, Yingwei Chen, Eun Jung Choi, Yihong Chen, Dana Motabar, Tsega Solomon, Richard Simmerman, Thomas Kauffman, D. Travis Gallagher, John Orban, Philip N. Bryan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
In this work the authors investigate the structure-sequence dependance. The ability to design and characterize proteins at interfaces between three common folds suggests that fold switching is an intrinsic feature of protein folding language and like
Externí odkaz:
https://doaj.org/article/9524664bc44a413a9ca8a35fb258616e
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2022-2038 (2022)
Few recurrent DNA mutations are seen in aggressive canine B cell lymphomas (cBCL), suggesting other frequent drivers. The methylated island recovery assay (MIRA-seq) or methylated CpG-binding domain sequencing (MBD-seq) was used to define the genome-
Externí odkaz:
https://doaj.org/article/71bdff6e90694378bb51935c4f2db5fb
Autor:
Alana R. Rodney, Zachary L. Skidmore, Jennifer K. Grenier, Obi L. Griffith, Andrew D. Miller, Shirley Chu, Faraz Ahmed, Jeffrey N. Bryan, Santiago Peralta, Wesley C. Warren
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Feline oral squamous cell carcinoma (FOSCC) is a cancer of the squamous cell lining in the oral cavity and represents up to 80% of all oral cancers in cats, with a poor prognosis. We have used whole exome sequencing (WES) and RNA sequencing of the tu
Externí odkaz:
https://doaj.org/article/ebfd0b050cca416e8f39ac5ad5dc3f0a
Autor:
Carissa J. Norquest, Charles A. Maitz, Deborah A. Keys, Melanie Moore, Jeffrey N. Bryan, Tara J. Ehling, Jimmy C. Lattimer, Brian K. Flesner
Publikováno v:
Veterinary Medicine and Science, Vol 8, Iss 3, Pp 1013-1024 (2022)
Abstract Background Radiation therapy (RT) is used for local pain alleviation in dogs with appendicular osteosarcoma (OS), especially among dogs that are poor surgical candidates for amputation. However, many historical reports of fractionated protoc
Externí odkaz:
https://doaj.org/article/faee43ee59bf42c7aec3a7afa491e82b
Autor:
E. Courtney Henry, Matthew Strugari, George Mawko, Kimberly Brewer, David Liu, Andrew C. Gordon, Jeffrey N. Bryan, Charles Maitz, James J. Karnia, Robert Abraham, S. Cheenu Kappadath, Alasdair Syme
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/b1139aa6b0984d36a265113fcdcd112a
Autor:
Eric A. Stahlberg, Mohamed Abdel-Rahman, Boris Aguilar, Alireza Asadpoure, Robert A. Beckman, Lynn L. Borkon, Jeffrey N. Bryan, Colleen M. Cebulla, Young Hwan Chang, Ansu Chatterjee, Jun Deng, Sepideh Dolatshahi, Olivier Gevaert, Emily J. Greenspan, Wenrui Hao, Tina Hernandez-Boussard, Pamela R. Jackson, Marieke Kuijjer, Adrian Lee, Paul Macklin, Subha Madhavan, Matthew D. McCoy, Navid Mohammad Mirzaei, Talayeh Razzaghi, Heber L. Rocha, Leili Shahriyari, Ilya Shmulevich, Daniel G. Stover, Yi Sun, Tanveer Syeda-Mahmood, Jinhua Wang, Qi Wang, Ioannis Zervantonakis
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
We are rapidly approaching a future in which cancer patient digital twins will reach their potential to predict cancer prevention, diagnosis, and treatment in individual patients. This will be realized based on advances in high performance computing,
Externí odkaz:
https://doaj.org/article/46e800c638964bf3bdfa34d7236e108c
Autor:
Aleksey Yevtodiyenko, Arkadiy Bazhin, Pavlo Khodakivskyi, Aurelien Godinat, Ghyslain Budin, Tamara Maric, Giorgio Pietramaggiori, Sandra S. Scherer, Marina Kunchulia, George Eppeldauer, Sergey V. Polyakov, Kevin P. Francis, Jeffrey N. Bryan, Elena A. Goun
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Bioluminescence imaging tends to rely on transgenic luciferase-expressing cells and animals. Here the authors report a portable bioluminescent system to non-invasively measure intra- and extracellular enzymes in vivo in non-transgenic animals which d
Externí odkaz:
https://doaj.org/article/cd73326c35744d1ea4308c3e175f26b0