Výsledky vyhledávání - "N Borregaard"

Secondary necrotic neutrophils release interleukin-16C and macrophage migration inhibitory factor from stores in the cytosol

Autor: Werner Solbach, C M Karsten, Tamás Laskay, Sonja Möller, N Borregaard, M Agthe, S Roth, Sarah Eickhoff

Publikováno v: Cell Death Discovery

Neutrophils harbor a number of preformed effector proteins that allow for immediate antimicrobial functions without the need for time-consuming de novo synthesis. Evidence indicates that neutrophils also contain preformed cytokines, including interle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f371e17a443cd9552cf688810905a17
https://doi.org/10.1038/cddiscovery.2015.56

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Patient education—a strategy for prevention of infections caused by permanent central venous catheters in patients with haematological malignancies: a randomized clinical trial

Autor: M. Tvede, Lis Adamsen, T. Møller, N. Borregaard

Publikováno v: Journal of Hospital Infection. 61:330-341

A functioning tunnelled central venous catheter (CVC) is a crucial device for patients with haematological malignancies receiving high-dose intravenous chemotherapy. Despite the advantages, CVC infections are a major cause of sepsis and prolonged hos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee29974fbb358898a904ef61da52643e
https://doi.org/10.1016/j.jhin.2005.01.031

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Glycosylation of Natural Human Neutrophil Gelatinase B and Neutrophil Gelatinase B-Associated Lipocalin

Autor: T Bratt, N Borregaard, S Masure, Taj S. Mattu, David Harvey, Pauline M. Rudd, Raymond A. Dwek, Ghislain Opdenakker, P. E. Van den Steen, J Van Damme, Bernhard Kuster, Mark R. Wormald

Publikováno v: Rudd, P, Mattu, T, Masure, S, Bratt, T, Van Den Steen, P, Wormald, M, Küster, B, Harvey, D, Borregaard, N, Van Damme, J, Dwek, R & Opdenakker, G 1999, ' Glycosylation of natural human neutrophil Gelatinase B and neutrophil gelatinase B-associated lipocalin ', Biochemistry, vol. 38, pp. 13937-13950 .

Gelatinase B is a matrix metalloproteinase (MMP-9) involved in tissue remodeling, development, cancer, and inflammation. Neutrophils produce three major forms of (pro)gelatinase B: 92 kDa monomers, homodimers, and complexes of gelatinase B covalently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd0d1889aadba30573bcec49bd6be64
https://doi.org/10.1021/bi991162e

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A family with chronic haemolysis and selective accumulation of erythrocyte CDP-choline

Autor: N Borregaard, A Petersen

Publikováno v: Leukemia. 11:1373-1376

In this paper, we report a family with compensated chronic haemolysis where the only erythrocyte abnormality detected was an increased level of erythrocyte CDP-choline. Using 31 P-NMR spectroscopy and enzymatic analysis the possibility of a pyrimidin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da61ed8bee49395966baebfcaafcbea
https://doi.org/10.1038/sj.leu.2400689

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Apoptosis following interleukin-2 withdrawal from T cells: evidence for a regulatory role of CD 18 (β2-integrin) molecules

Autor: Niels Ødum, M. Nielsen, A. Svejgaard, N. Borregaard, Paul Gladstone, Carsten Röpke, J. A. Ledbetter

Publikováno v: Tissue Antigens. 48:127-135

Following a successful immune response against invading microorganisms, the majority of activated T cells is eliminated, while a minor fraction survives as memory T cells. A decline in T lymphocyte growth factors such as interleukin-2 (IL-2) appears

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab966b28df6b263ff3120d95bf59513d
https://doi.org/10.1111/j.1399-0039.1996.tb02617.x

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Neutrophil granules in health and disease

Autor: M, Häger, J B, Cowland, N, Borregaard

Publikováno v: Journal of internal medicine. 268(1)

Neutrophil granules store proteins that are critically important for the neutrophil to move from the vascular bed to tissues and to kill microorganisms. This is illustrated in nature when individual proteins are deleted due to inherited mutations of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2d4eea1b55e507dd1a469fc4f9c08000
https://pubmed.ncbi.nlm.nih.gov/20497300

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Mixed Enzyme-Linked Immunosorbent Assay (MELISA) for HLA Class I Antigen: a Plasma Membrane Marker

Autor: N. Borregaard, O. W. Bjerrum

Publikováno v: Scandinavian Journal of Immunology. 31:305-313

This study introduces a simple, reproducible assay for HLA class I antigen using antibodies against beta 2-microglobulin and the heavy chain on HLA. The sandwich technique was named mixed enzyme-linked immunosorbent assay (MELISA), and was designed f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b29c5f48df00843c4531c04d7c9d7b3
https://doi.org/10.1111/j.1365-3083.1990.tb02773.x

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The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gelatinase-associated lipocalin (NGAL). Modulation of MMP-9 activity by NGAL

Autor: L, Yan, N, Borregaard, L, Kjeldsen, M A, Moses

Publikováno v: The Journal of biological chemistry. 276(40)

Detection of matrix metalloproteinase (MMP) activities in the urine from patients with a variety of cancers has been closely correlated to disease status. Among these activities, the presence of a group of high molecular weight (HMW) MMPs independent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4db733218721cd0d7a717814fe25269b
https://pubmed.ncbi.nlm.nih.gov/11486009

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