Zobrazeno 1 - 10
of 222
pro vyhledávání: '"N Beckett"'
Autor:
Ha Won Lee, Carla O’Reilly, Alex N. Beckett, Duane G. Currier, Taosheng Chen, Christopher DeRenzo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-13 (2024)
Abstract Background CAR T cell therapy is a promising approach to improve outcomes and decrease toxicities for patients with cancer. While extraordinary success has been achieved using CAR T cells to treat patients with CD19-positive malignancies, mu
Externí odkaz:
https://doaj.org/article/67caf5f0c48247379501ee94399f1f1a
Autor:
Stephen Gottschalk, Phuong Nguyen, Christopher DeRenzo, Giedre Krenciute, Alex N Beckett, Peter Chockley, Shondra M Pruett-Miller, Peter Vogel, Heather Sheppard
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background CD47 is an attractive immunotherapeutic target because it is highly expressed on multiple solid tumors. However, CD47 is also expressed on T cells. Limited studies have evaluated CD47-chimeric antigen receptor (CAR) T cells, and the role o
Externí odkaz:
https://doaj.org/article/0dce8e42cb164bc3af9c4f217878a8e2
Autor:
Ha Won Lee, Carla O’Reilly, Alex N. Beckett, Duane G. Currier, Taosheng Chen, Christopher DeRenzo
CAR T cell therapy is a promising approach to improve outcomes and decrease toxicities for patients with cancer. While extraordinary success has been achieved using CAR T cells to treat patients with CD19-positive malignancies, multiple obstacles hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1883e30c8c002e4a849efae87319e2e4
https://doi.org/10.1101/2023.05.26.542130
https://doi.org/10.1101/2023.05.26.542130
Autor:
Trey Ideker, Jason F. Kreisberg, John Paul Shen, Wei Zhang, Tina Wang, Alex N. Beckett, Sean N. Tang, Kyle S. Sanchez, Katherine Licon, Ana Bojorquez-Gomez, Justin K. Huang, Nam Bui
Supplemental Table 1. Descriptions of the CpG-associated genes reveal a predominance of genes that function in MHC class or skin/connective tissue structure. Supplemental Table 2. Consistently hypomethylated genes in NSD1 disrupted cell lines. Supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fed5c822ba7545a8b993dbc11f3245
https://doi.org/10.1158/1535-7163.22504449
https://doi.org/10.1158/1535-7163.22504449
Autor:
Trey Ideker, Jason F. Kreisberg, John Paul Shen, Wei Zhang, Tina Wang, Alex N. Beckett, Sean N. Tang, Kyle S. Sanchez, Katherine Licon, Ana Bojorquez-Gomez, Justin K. Huang, Nam Bui
Human papillomavirus (HPV)–negative head and neck squamous cell carcinoma (HNSCC) represents a distinct classification of cancer with worse expected outcomes. Of the 11 genes recurrently mutated in HNSCC, we identify a singular and substantial surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45620686ac75a65efa431d44d592c0c4
https://doi.org/10.1158/1535-7163.c.6537738.v1
https://doi.org/10.1158/1535-7163.c.6537738.v1
Autor:
Christophe Martinaud, Tom Scorer, Miquel Lozano, Andrew Miles, Gary Fitchett, Alhassane Ba, Agneta Wikman, Patrik Nimberger‐Hansson, Stefan Enbuske, Miloš Bohoněk, Dana Devine, Andrew N. Beckett, Dora Mbanya, France T’Sas, Julie Degueldre, Marine Chueca, Emmanuel Dedome, Torunn Apelseth, Geir Strandenes, Silvano Wendel, Roberta Fachini, Adam Olszewski, Cyrille Dupont, Elon Glassberg, Eilat Shinar, Audra L. Taylor, Jason B. Corley, Veera Sekaran Nadarajan, Nancy Dunbar
Publikováno v:
Vox Sanguinis. 116:924-929
Autor:
Milad Nazarzadeh, Zeinab Bidel, Dexter Canoy, Emma Copland, Derrick A Bennett, Abbas Dehghan, George Davey Smith, Rury R Holman, Mark Woodward, Ajay Gupta, Amanda I Adler, Malgorzata Wamil, Naveed Sattar, William C Cushman, Richard J McManus, Koon Teo, Barry R Davis, John Chalmers, Carl J Pepine, Kazem Rahimi, L Agodoa, A Algra, F W Asselbergs, N Beckett, E Berge, H Black, F P J Brouwers, M Brown, C J Bulpitt, B Byington, J Cutler, R B Devereaux, J Dwyer, R Estacio, R Fagard, K Fox, T Fukui, Y Imai, M Ishii, S Julius, Y Kanno, S E Kjeldsen, J Kostis, K Kuramoto, J Lanke, E Lewis, J Lewis, M Lievre, L H Lindholm, S Lueders, S MacMahon, G Mancia, M Matsuzaki, M H Mehlum, S Nissen, H Ogawa, T Ogihara, T Ohkubo, C Palmer, A Patel, M Pfeffer, N R Poulter, H Rakugi, G Reboldi, C Reid, G Remuzzi, P Ruggenenti, T Saruta, J Schrader, R Schrier, P Sever, P Sleight, J A Staessen, H Suzuki, L Thijs, K Ueshima, S Umemoto, W H van Gilst, P Verdecchia, K Wachtell, P Whelton, L Wing, Y Yui, S Yusuf, A Zanchetti, Z Y Zhang, C Anderson, C Baigent, BM Brenner, R Collins, D de Zeeuw, J Lubsen, E Malacco, B Neal, V Perkovic, B Pitt, A Rodgers, P Rothwell, G Salimi-Khorshidi, J Sundström, F Turnbull, G Viberti, J Wang
Publikováno v:
Nazarzadeh, M, Bidel, Z, Canoy, D, Copland, E, Bennett, D A, Dehghan, A, Davey Smith, G, Holman, R R, Woodward, M, Gupta, A, Adler, A I, Wamil, M, Sattar, N, Cushman, W C, McManus, R J, Koon, T, Davis, B R, Chalmers, J, Pepine, C J & Rahimi, K 2022, ' Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes : an individual participant-level data meta-analysis ', Lancet Diabetes and Endocrinology, vol. 10, no. 9, pp. 645-654 . https://doi.org/10.1016/S2213-8587(22)00172-3
Background Controversy exists as to whether the threshold for blood pressure-lowering treatment should differ between people with and without type 2 diabetes. We aimed to investigate the effects of blood pressure-lowering treatment on the risk of maj
Autor:
Bob Jacobs, Riri Uchida, Coby Dodelson, Christine Brzezinski, Hunter Kelley, Matthew Schall, Thor D. Stein, Madeleine E. Garcia, Ann C. McKee, Melissa D. Bauman, Hyunsoo Shin, Sarah Svirsky, Cynthia M. Schumann, N. Beckett Shea-Shumsky, Allyson Alexander, Morgan Pothast, Allysa Warling
Publikováno v:
The Journal of comparative neurology, vol 529, iss 7
J Comp Neurol
J Comp Neurol
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disorder that is associated with repetitive head impacts. Neuropathologically, it is defined by the presence of perivascular hyperphosphorylated tau aggregates in cortical tissue (McKee et
Introduction of an enhanced recovery protocol into a laparoscopic living donor nephrectomy programme
Autor:
J Monserez, Aisling E. Courtney, James McDaid, K Kerr, Hannah Magowan, P Veitch, N Beckett, S Kanabar, Tim Brown, F Magill
Publikováno v:
Ann R Coll Surg Engl
Introduction Living-donor renal transplantation is the optimal treatment for patients with end-stage renal disease. The rate of living donation in the UK is sub-optimal, and potential donor concerns regarding postoperative recovery may be contributor
Publikováno v:
The new normal? Novel and remote strategies for pulmonary rehabilitation.
IntroductionThe most common symptoms of ‘Long COVID’ which is defined as symptoms >12 weeks post COVID infection, are breathlessness and fatigue. Breathing retraining and holistic management for patients suffering with ongoing symptoms of COVID h