Výsledky vyhledávání - "N B Patterson"

Inflammatory cytokines IFN-gamma plus TNF-alpha induce regulated expression of CD80 (B7-1) but not CD86 (B7-2) on murine fibroblasts

Autor: K Pechhold, N B Patterson, N Craighead, K P Lee, C H June, D M Harlan

Publikováno v: The Journal of Immunology. 158:4921-4929

Optimal T cell activation requires signals delivered via both the TCR and the costimulatory receptors. Considerable experimental data now suggest that this costimulatory signal is generated predominantly by CD28 when engaged by its ligands CD80 (B7-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8764e853e72edd2b63ee99b1bc4c80f2
https://doi.org/10.4049/jimmunol.158.10.4921

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Very-low-dose streptozotocin induces diabetes in insulin promoter-mB7-1 transgenic mice

Autor: D. M. Harlan, M. A. Barnett, R. Abe, K. Pechhold, N. B. Patterson, G. S. Gray, C. H. June

Publikováno v: Diabetes. 44:816-823

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3afbe6ad4e3bdc67c5b0e3d9f24a180
https://doi.org/10.2337/diabetes.44.7.816

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Induction therapy with monoclonal antibodies specific for CD80 and CD86 delays the onset of acute renal allograft rejection in non-human primates

Autor: A D, Kirk, D K, Tadaki, A, Celniker, D S, Batty, J D, Berning, J O, Colonna, F, Cruzata, E A, Elster, G S, Gray, R L, Kampen, N B, Patterson, P, Szklut, J, Swanson, H, Xu, D M, Harlan

Publikováno v: Transplantation. 72(3)

CD80 and CD86 (also known as B7-1 and B7-2, respectively) are both ligands for the T cell costimulatory receptors CD28 and CD152. Both CD80 and CD86 mediate T cell costimulation, and as such, have been studied for their role in promoting allograft re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ab0edd2ed34a8790fb370f515446b41
https://pubmed.ncbi.nlm.nih.gov/11502964

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