Zobrazeno 1 - 10
of 11
pro vyhledávání: '"N B Modi"'
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 35(8)
Pentosan polysulfate sodium (PPS) is the active ingredient in ELMIRON, a drug approved for the relief of bladder pain associated with interstitial cystitis. The study objective was to characterize the pharmacokinetic and metabolic profiles of PPS fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7c64f7ba0365029d1b465d2025f717
https://pubmed.ncbi.nlm.nih.gov/16278190
https://pubmed.ncbi.nlm.nih.gov/16278190
Autor:
N B, Modi
Publikováno v:
IDrugs : the investigational drugs journal. 2(4)
CytRx is developing Flocor, an amphipathic copolymer, as a potential treatment for acute sickle cell crisis and acute respiratory distress syndrome (ARDS)/acute lung injury 1. It is currently undergoing phase III clinical trials for the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcdbfce3e87991dbb6a47d256e920466
https://pubmed.ncbi.nlm.nih.gov/16158356
https://pubmed.ncbi.nlm.nih.gov/16158356
Publikováno v:
Biopharmaceuticsdrug disposition. 21(1)
The effect of a high-fat meal on the pharmacokinetics of OROS(R) (methylphenidate HCl), an osmotic controlled-release formulation of methylphenidate HCl, was investigated in healthy subjects. Mean peak methylphenidate plasma concentrations occurred s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc1ec8eda84c6e886b0096b5f7f290a4
https://pubmed.ncbi.nlm.nih.gov/11038435
https://pubmed.ncbi.nlm.nih.gov/11038435
Publikováno v:
Journal of clinical pharmacology. 40(10)
Methylphenidate hydrochloride (HCl) is frequently used for the treatment of attention deficit/hyperactivity disorder (ADHD). A study was conducted in healthy subjects to evaluate the dose-ranging pharmacokinetics of 18, 36, and 54 mg methylphenidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1de0423885402164ab8f8774cb77edc0
https://pubmed.ncbi.nlm.nih.gov/11028253
https://pubmed.ncbi.nlm.nih.gov/11028253
Publikováno v:
Journal of clinical pharmacology. 40(4)
Methylphenidate is used for the treatment of attention deficit hyperactivity disorder (ADHD). OROS (methylphenidate HCl) is an osmotic controlled-release delivery system designed for once-daily oral dosing. The pharmacokinetics of OROS (methylphenida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a4d2c5b187005b6d149a25b70eae318
https://pubmed.ncbi.nlm.nih.gov/10761165
https://pubmed.ncbi.nlm.nih.gov/10761165
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(1)
Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis and in pathological processes such as tumor growth, rheumatoid arthritis, and ocular neovascularization. A recombinant humanized monoclonal antibody (rhuMAb), rhuMAb VEGF,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f19f85674045fa8df7da0be435606611
https://pubmed.ncbi.nlm.nih.gov/9862791
https://pubmed.ncbi.nlm.nih.gov/9862791
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 704(1-2)
We describe a method for measuring Ro 48-3656 in EDTA rat plasma by neutral pH, reversed-phase high-performance liquid chromatography using a 1.5-microm nonporous silica, C18 analytical column and UV absorbance detection to support pharmacokinetic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0582d53148e5c12f4b153b946d291bd7
https://pubmed.ncbi.nlm.nih.gov/9518155
https://pubmed.ncbi.nlm.nih.gov/9518155
Publikováno v:
Thrombosis and haemostasis. 79(1)
The rapid clearance of t-PA from plasma requires administration by intravenous (I.V.) infusion. A slower clearing, fibrin-specific rt-PA variant may allow single intravenous bolus administration, thereby simplifying dosing. This study was designed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e84e31791d36aacbad3b88d11ad8818
https://pubmed.ncbi.nlm.nih.gov/9459338
https://pubmed.ncbi.nlm.nih.gov/9459338
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(1)
Vascular endothelial growth factor (VEGF) produces beneficial angiogenesis in animal models of coronary and peripheral ischemia. However, intravenous bolus injection of Chinese hamster ovary cell (CHO)-derived VEGF produces adverse effects on hemodyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac753eb53738ada18e7ee1006b30ff91
https://pubmed.ncbi.nlm.nih.gov/9435167
https://pubmed.ncbi.nlm.nih.gov/9435167
Publikováno v:
Pharmaceutical research. 11(2)
The in vivo phenobarbital removal characteristics of three brands of activated charcoal (Actidose, Charcoaid, Superchar) were studied in normal volunteers using a system analysis approach. The subjects received a 200-mg dose of oral or intravenous ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5bd7ad4bdba6706af56b497df0667cf
https://pubmed.ncbi.nlm.nih.gov/8165195
https://pubmed.ncbi.nlm.nih.gov/8165195