Zobrazeno 1 - 10
of 24
pro vyhledávání: '"N B, Westwood"'
Publikováno v:
European Journal of Haematology. 51:228-232
Patients with polycythaemia and normal controls have been studied to establish and subsequently test non-conventional criteria for the diagnosis of primary polycythaemia (primary proliferative polycythaemia, polycythaemia vera) as compared with conve
Autor:
B. Sawyer, N. B. Westwood, Atul Mehta, J. Acharya, A.K. Burroughs, M. Messinezy, Thomas C. Pearson
Publikováno v:
European Journal of Haematology. 55:315-321
Some patients with an early or latent myeloproliferative disorder (MPD) present with Budd-Chiari syndrome (BCS, hepatic vein thrombosis). Cell culture analysis of erythroid progenitors (BFU-E) can be used to discriminate primary from secondary MPD an
Publikováno v:
European Journal of Haematology. 53:163-167
25 patients with idiopathic erythrocytosis (absolute increase in red cell mass without conventional criteria of primary polycythaemia or known underlying cause) have been further studied for evidence of primary or secondary polycythaemia. Additional
Autor:
L J Holland, N. B. Westwood, Thomas C. Pearson, M. Messinezy, R. J. Grace, AS Lawrie, B. Sawyer
Publikováno v:
Clinical & Laboratory Haematology. 16:139-148
Summary. Traditional diagnostic criteria for primary thrombocythaemia (PT) remain essentially negative, aiming to exclude other myeloproliferative disorders and causes of reactive thrombocytosis (RT). It would be useful to have positive markers. We h
Publikováno v:
British Journal of Cancer
Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK
Autor:
M.H. Cummings, B. Sawyer, Peter H. Sönksen, Thomas C. Pearson, David Russell-Jones, N. B. Westwood, Emanuel Christ
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:2985-2990
Total body water (TBW) is reduced in adult GH deficiency (GHD) largely due to a reduction of extracellular water. It is unknown whether total blood volume (TBV) contributes to the reduced extracellular water in GHD. GH and insulin-like growth factor
Publikováno v:
British Journal of Haematology. 86:468-474
Summary. Circulating haemopoietic progenitor cells from premature infants were assessed for their ability to respond to interleukin 3, granulocyte-macrophage colony stimulating factor and stem cell factor (SCF) in vitro. All three cytokines increased
Publikováno v:
Leukemia & Lymphoma. 14:441-446
Patients with B-cell chronic lymphocytic leukaemia (B-CLL) have an increased susceptibility to infection. Quantitative abnormalities of T-cells have been previously reported in B-CLL, although the relationship between such abnormalities and the incid
Autor:
D Muggleston, C Bell-Witter, Gauranga Majumdar, J K Phillips, N B Westwood, Thomas C. Pearson
Publikováno v:
Leukemia & Lymphoma. 9:173-176
In 30 patients with multiple myeloma (MM) and mild to moderate anaemia (mean Hb 107 g/l, 95% confidence limit (CL) 102-113) but no evidence of renal failure (serum creatinine < 110 mumol/l), serum erythropoietin (EPO) showed significant inverse logar
Autor:
R. J. Duncombe, I. Basnak, S. G. Rahim, G. P. Otter, G. W. Hardy, G. Mills, M. Pietrarelli, N. B. Westwood, Richard T. Walker
Publikováno v:
ChemInform. 29
(E)-5-(2-Bromovinyl)-2'-deoxy-4'-thiouridine (S-BVDU) is a potent antiherpesvirus agent and its use in gene therapy as an anticancer agent has recently been described. We here outline 2 efficient methods for the synthesis of S-BVDU. The decision as t