Zobrazeno 1 - 10 of 213 pro vyhledávání: '"N A Mitchison"'
1
Positive selection in dNTPase SAMHD1 throughout mammalian evolution
Autor: Christopher Ruis, Richard A. Goldstein, Jonathan P. Stoye, Ariberto Fassati, Christopher Monit, Bart Szafran, Ming-Han Chloe Tsai, N. Avrion Mitchison, Elizabeth R. Morris, Grant Thiltgen, Kate N. Bishop, Ian A. Taylor
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Significance Animals defend themselves from viral infection using innate immunity proteins that disrupt various stages of the virus life cycle. In response, viruses produce proteins that bind these host factors and compromise their activity, resultin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61a16f5a13d7751b135333c77dc2b4b
https://doi.org/10.1073/pnas.1908755116
Zobrazit plný text záznamu
2
Akademický článek
Immune Privilege as an Intrinsic CNS Property: Astrocytes Protect the CNS against T-Cell-Mediated Neuroinflammation
Autor: Ulrike Gimsa, N. Avrion Mitchison, Monika C. Brunner-Weinzierl
Publikováno v: Mediators of Inflammation, Vol 2013 (2013)
Astrocytes have many functions in the central nervous system (CNS). They support differentiation and homeostasis of neurons and influence synaptic activity. They are responsible for formation of the blood-brain barrier (BBB) and make up the glia limi
Externí odkaz: https://doaj.org/article/360db5e79905445bb125af72a3bb2247
Zobrazit plný text záznamu
3
Genetic disease in India and the West compared: provisional analysis of population dynamics
Autor: N A Mitchison, Timothy J. Mitchison
Publikováno v: Journal of Genetics. 97:307-309
The Indian Genetic Disease Database (IGDD) and Online Mendelian Inheritance in Man (OMIM) survey human populations that have different climate histories. Comparison of the two shows an outstanding difference in the relative frequency of recessive dis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::082f8f701098005636d38860808d524b
https://doi.org/10.1007/s12041-017-0871-y
Zobrazit plný text záznamu
10
The low frequency of recessive disease: insights from ENU mutagenesis, severity of disease phenotype, GWAS associations, and demography: an analytical review
Autor: Robert P. Erickson, N. Avrion Mitchison
Publikováno v: Journal of Applied Genetics. 55:319-327
A survey of a select panel of 14 genetic diseases with mixed inheritance confirms that, while autosomal recessive (AR) disease genes are more numerous than autosomal dominant (AD) or X-linked (XL) ones, they make a smaller average contribution to dis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64678869d30a8c35bc3a290e4890327c
https://doi.org/10.1007/s13353-014-0203-3
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje