Zobrazeno 1 - 10
of 32
pro vyhledávání: '"N A C S Wong"'
Publikováno v:
Journal of Clinical Pathology. 65:228-231
Aims To examine the clinicopathological features of a series of penile melanomas and screen for mutations in the BRAF and KIT genes, which are seen in melanomas from other sites. Methods and results 12 patients with penile melanoma were identified ov
Autor:
L A Jamieson, V E Save, C Han, F A Carey, R D G Malcomson, D H Brewster, Awatif Al-Nafussi, N A C S Wong, A G Nayar, R Young
Publikováno v:
Histopathology. 43:118-126
Aims Whether immunohistochemical markers increase accuracy in predicting prognosis for gastrointestinal stromal tumours (GISTs) remains uncertain. However, past studies have used only small, heterogeneous patient groups. Our aim was to test previousl
Autor:
Nicholas J Mayer, Joachim Diebold, Honora C Mckenzie, Ian W. Brock, Janice A. Royds, David J. Harrison, R. G. Morris, H. Gilmour, Doris Mayr, Catriona E Anderson, N A C S Wong
Publikováno v:
Human Pathology. 34:580-588
It is unclear whether and how cyclin D1 and/or p21(WAF1/CIP1) dysregulation contribute to ulcerative colitis (UC)-related inflammation and colorectal carcinogenesis. Cases of quiescent UC (QUC; n = 15), active UC (AUC; n = 23), UC-related dysplasia (
Autor:
Massimo Pignatelli, N A C S Wong
Publikováno v:
The American Journal of Pathology. 160:389-401
An important role for beta-catenin pathways in colorectal carcinogenesis was first suggested by the protein's association with adenomatous polyposis coli (APC) protein, and by evidence of dysregulation of beta-catenin protein expression at all stages
Publikováno v:
Acta Cytologica. 46:723-727
BACKGROUND: There are few published data on the cytologic features of gastrointestinal stromal tumors (GISTs) in ascitic fluid and whether these features may mimic those of other malignancies. CASE: An 80-year-old woman presented with ascites associa
Autor:
Jane M Blazeby, Natalie S Blencowe, R. N. Whistance, Prem Chana, D. Stevens, Stephen Falk, N. A. C. S. Wong
Publikováno v:
Journal of the National Cancer Institute. 106(9)
Background The use of neoadjuvant therapy before surgery for gastrointestinal cancer is increasing; however, patients may not complete both treatment components. Understanding completion rates of each treatment stage is necessary for treatment evalua
Autor:
N A C S Wong, David J. Harrison
Publikováno v:
Histopathology. 39:221-234
It is recognized that ulcerative colitis (UC) predisposes to the development of colorectal adenocarcinoma (CRC), and the molecular pathway for this process differs from that for sporadic CRCs. However, several important details regarding the risk fac
Autor:
Awatif Al-Nafussi, N A C S Wong
Publikováno v:
Histopathology. 38:387-402
Intra-abdominal spindle cell lesions are uncommon and often present a diagnostic challenge. An important group of such lesions are the gastrointestinal stromal tumours. Other intra-abdominal spindle cell lesions include fibromatosis, various sarcomas
Publikováno v:
Histopathology. 37:108-114
Aims : To assess whether Ki67 and p53 immunostaining may assist the diagnosis and grading of ulcerative colitis-related dysplasia. Methods and results : Location of Ki67 staining and location and intensity of p53 staining were assessed in ulcerative
Publikováno v:
Toxicology Letters. 115:17-22
The gene encoding the xenobiotic-metabolising microsomal enzyme, epoxide hydrolase (mEPHX), shows two common mutations, i.e. at exons 3 and 4. It is unknown how these genetic polymorphisms relate to risk of developing alcoholic liver disease (ALD) an