Zobrazeno 1 - 5
of 5
pro vyhledávání: '"N A, Pyszczynski"'
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 27(1)
Prednisolone (Pred) and sirolimus (SIR) are immunosuppressive compounds acting through different mechanisms with moderate synergism found in vitro. Both drugs are metabolized partly by CYP3A enzymes. After i.v. administration of placebo, Pred (5 mg/k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd1b87d198016f0e383b4f2db3838a6f
https://pubmed.ncbi.nlm.nih.gov/10533695
https://pubmed.ncbi.nlm.nih.gov/10533695
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 26(6)
Dose-dependent and repeated-dose effects of methylprednisolone (MPL) on down-regulation of glucocorticoid receptor messenger RNA (GR mRNA) and GR density, as well as tyrosine aminotransferase (TAT) mRNA and TAT induction by receptor/gene-mediated mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::849dd76640b88d3f8ea4a0da36ea9c50
https://pubmed.ncbi.nlm.nih.gov/10485078
https://pubmed.ncbi.nlm.nih.gov/10485078
Publikováno v:
Transplantation. 65(9)
Cyclosporine (CsA), prednisolone (Pred), and sirolimus (Sir) are immunosuppressive compounds inhibiting lymphocyte proliferation at the cytokine gene transcription (CsA and Pred) or signal transduction (Sir) levels.Double- and triple-drug interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c246de2cf9148a4d7470b3b408b7ba81
https://pubmed.ncbi.nlm.nih.gov/9603169
https://pubmed.ncbi.nlm.nih.gov/9603169
Publikováno v:
Pharmaceutical research. 10(10)
A liposomal formulation of methylprednisolone (L-MPL) was developed to improve localization of this immunosuppressant in lymphatic tissues. Liposomes containing MPL were formulated from a mixture of phosphatydylcholine and phosphatydylglycerol (molar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a9fdb74709bf8a78ef2bdb7b05fd445
https://pubmed.ncbi.nlm.nih.gov/8272400
https://pubmed.ncbi.nlm.nih.gov/8272400
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 250(3)
The pharmacokinetics and pharmacodynamic response to prednisolone were examined in dietary-induced obese rats and matched controls. Pharmacokinetic parameters were examined in absolute and weight normalized terms. After an i.v. dose (range, 4.0-6.3 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5ed3275e5898d467292c59890c059b3
https://pubmed.ncbi.nlm.nih.gov/2778721
https://pubmed.ncbi.nlm.nih.gov/2778721