Výsledky vyhledávání - "N A, Okorokova"

The Nature of Thermal Stability of Prokaryotic Nucleoside Phosphorylases

Autor: T. N. Safonova, Konstantin M. Polyakov, V. P. Veiko, A. N. Antipov, N. A. Okorokova, N. N. Mordkovich

Publikováno v: Applied Biochemistry and Microbiology. 56:662-670

A library of strains producing recombinant nucleoside phosphorylases (NPs) and their mutant and hybrid forms from various mesophilic and extremophilic microorganisms was constructed based on Escherichia coli cells. Substrates were shown to stabilize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c14d859524281be9c7f252e03eb4f56b
https://doi.org/10.1134/s0003683820060125

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Cloning of Nucleoside Phosphorylase Genes from the Extremophilic Bacterium Halomonas chromatireducens AGD 8-3 with the Construction of Recombinant Producer Strains of These Proteins and the Study of Their Enzymatic Properties

Autor: N. N. Mordkovich, T. V. Khijniak, A. N. Antipov, N. A. Okorokova, V. P. Veiko

Publikováno v: Applied Biochemistry and Microbiology. 56:37-43

Thymidine phosphorylase (deoA) and purine nucleoside phosphorylase (deoD) genes from the extremophilic bacterium Halomonas chromatireducens AGD 8-3 have been cloned. Expression plasmids were constructed, and highly efficient recombinant producer stra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5dd257b1bdf5773f56b191c347332aaf
https://doi.org/10.1134/s0003683820010020

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Synthesis and dielectric properties of metal-ceramic nanostructures

Autor: A. A. Farmakovskaya, N. S. Okorokova, A. V. Perchenok

Publikováno v: E3S Web of Conferences. 371:04003

In this work, electrical properties of metal-dielectric nanocom-posites with amorphous structure and multilayer films based on them have been investigated. It is shown that the concentration dependences of the electrical resistance of the composites

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85ff58883f671aaee0c200b68888f621
https://doi.org/10.1051/e3sconf/202337104003

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PURIFICATION OF ALKALINE ELECTROLYTE FROM DISSOLVED REACTION PRODUCTS DURING WORK OF THE AIR-ALUMINUM CHEMICAL CURRENT SOURCE

Autor: N. S. Okorokova, E. V. Suvorova, A. A. Farmakovskaya, A. V. Perchenok

Publikováno v: Periódico Tchê Química. 16:337-350

The relevance of the article is based on the fact that the state of work on the creation of power sources (PS) with AA chemical current sources (CCS) is at the stage of development and testing of prototypes. The purpose of this article is to calculat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d377f59d12f5739c648c17ffb53d4e61
https://doi.org/10.52571/ptq.v16.n33.2019.352_periodico33_pgs_337_350.pdf

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Study of Structural-Functional Organization of Nucleoside Phosphorylases of Gammaproteobacteria. Special Aspects of Functioning of Uridine Phosphorylase Phosphate-Binding Site

Autor: T. N. Safonova, A. N. Antipov, Konstantin M. Polyakov, V. P. Veiko, Valentin A. Manuvera, N. N. Mordkovich, N. A. Okorokova

Publikováno v: Applied Biochemistry and Microbiology. 54:12-20

Series of mutant genes of prokaryotic uridine phosphorylases (Shewanella oneidensis MR-1, Escherichia coli) were constructed, and the resulting strains-producers of the corresponding proteins were obtained. Proteins were purified, and their physicoch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31a5bfad21fdd3638d14cbb93db9622a
https://doi.org/10.1134/s0003683818010064

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Ribosomal DNA as DAMPs Signal for MCF7 Cancer Cells

Autor: Ekaterina A. Savinova, S. I. Kutsev, Ekaterina A. Kozhina, S. V. Kostyuk, N. A. Okorokova, Marina S. Konkova, N. N. Veiko, Lev N. Porokhovnik, Elena M. Malinovskaya, V. P. Veiko, Elizaveta S. Ershova

Publikováno v: Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology

Introduction: The cell free ribosomal DNA (cf-rDNA) is accrued in the total pool of cell free DNA (cfDNA) in some non-cancer diseases and demonstrates DAMPs characteristics. The major research questions: (1) How does cell free rDNA content change in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3559557e98ef732dba4458470a861a
https://doi.org/10.3389/fonc.2019.00445

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Increased Transfection of the Easily Oxidizable GC-Rich DNA Fragments into the MCF7 Breast Cancer Cell

Autor: N. A. Okorokova, S. V. Kostyuk, Marina S. Konkova, Ekaterina A. Savinova, Elizaveta S. Ershova, N. N. Mordkovich, Lev N. Porokhovnik, N. N. Veiko, Elena M. Malinovskaya, Tatiana A. Muzaffarova, Maria Borzikova, V. P. Veiko, S. I. Kutsev

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)

Objective. Easily oxidizable GC-rich DNA (GC-DNA) fragments accumulate in the cell-free DNA (cfDNA) of patients with various diseases. The human oxidized DNA penetrates the MCF7 breast cancer cells and significantly changes their physiology. It can b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3881addba5b5be12fa1821069b540d01
http://europepmc.org/articles/PMC6379852

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Solid reaction products and aluminate solutions that form during the operation of an air–aluminum chemical power supply

Autor: N. S. Okorokova, E. V. Suvorova, S. D. Sevruk, A. A. Farmakovskaya

Publikováno v: Russian Metallurgy (Metally). 2015:1174-1178

A solution to the set of problems concerning the solid reaction products and the aluminate solutions that form during the operation of an aluminum-closed power supply system for self-contained objects is proposed. The system is based on a resource-sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d03b80fc7f0c21defe5d88247f11ab1
https://doi.org/10.1134/s0036029515130194

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Structural and functional organization of the signal peptide of pro-enterotoxin B from Staphylococcus aureus

Autor: N. A. Okorokova, V. P. Veiko, N. N. Mordkovich

Publikováno v: Applied Biochemistry and Microbiology. 51:641-648

A series of genes of proenterotoxin B from Staphylococcus aureus containing signal peptide mutant forms was constructed in order to study the functional roles of the introduced mutations. It was shown that a continuous mutation in the n-region of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38b4bbf111da48d06b2d7f809f11c555
https://doi.org/10.1134/s0003683815060101

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