Zobrazeno 1 - 10
of 16
pro vyhledávání: '"N A, Meanwell"'
Publikováno v:
ChemInform. 22
Autor:
V K, Gribkoff, J T, Lum-Ragan, C G, Boissard, D J, Post-Munson, N A, Meanwell, J E, Starrett, E S, Kozlowski, J L, Romine, J T, Trojnacki, M C, Mckay, J, Zhong, S I, Dworetzky
Publikováno v:
Molecular pharmacology. 50(1)
Through expression of the cloned mouse (mSlo) or human (hSlo) large-conductance (BK) Ca(2+)-activated K+ channel in Xenopus laevis oocytes and HEK 293 cells, we characterized the effects of reported blockers and openers of BK channels to initiate the
Autor:
N A, Meanwell, M J, Rosenfeld, A K, Trehan, J J, Wright, C L, Brassard, J O, Buchanan, M E, Federici, J S, Fleming, M, Gamberdella, K S, Hartl
Publikováno v:
Drug design and discovery. 11(1)
2-[3-[2-(4,5-Diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid, 1, has been described as a non-prostanoid PGI2 mimetic that demonstrates anti-thrombotic properties of long duration in animal models of thrombosis. The effects of substitution and modificat
Autor:
N A, Meanwell, M J, Rosenfeld, A K, Trehan, J J, Wright, C L, Brassard, J O, Buchanan, M E, Federici, J S, Fleming, M, Gamberdella, G B, Zavoico
Publikováno v:
Journal of medicinal chemistry. 35(19)
4,5-Diphenyl-2-oxazolenonanoic acid (18b) was synthesized and found to inhibit ADP-induced aggregation of human platelets with an IC50 of 2.5 microM. Acid 18b displaced [3H]iloprost from human platelet membranes in a concentration-dependent fashion,
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 255(3)
Octimibate inhibited ADP- and collagen-induced platelet aggregation in human, rabbit and rat platelet-rich plasma. Washed human platelets treated with octimibate had elevated cyclic AMP (cAMP) levels and cAMP-dependent protein kinase activity. When w
Autor:
C. R. JOHNSON, N. A. MEANWELL
Publikováno v:
Chemischer Informationsdienst. 13
Publikováno v:
Chemischer Informationsdienst. 16
Autor:
C. R. JOHNSON, K. G. BIS, J. H. CANTILLO, N. A. MEANWELL, M. F. D. REINHARD, J. R. ZELLER, G. P. VONK
Publikováno v:
Chemischer Informationsdienst. 14
Publikováno v:
Chemischer Informationsdienst. 14
Autor:
N. A. MEANWELL, C. R. JOHNSON
Publikováno v:
Chemischer Informationsdienst. 13