Zobrazeno 1 - 10
of 105
pro vyhledávání: '"N A, Fuller"'
Publikováno v:
Brain and Spine, Vol 1, Iss , Pp 100744- (2021)
Externí odkaz:
https://doaj.org/article/1fdf59c3bb6948d5a949c14d93a9d0be
Autor:
Kelly N Z Fuller, Julie Allen, Roshan Kumari, Jephte Y Akakpo, Meghan Ruebel, Kartik Shankar, John P Thyfault
Publikováno v:
Journal of the Endocrine Society. 7
Compared with males, premenopausal women and female rodents are protected against hepatic steatosis and present with higher functioning mitochondria (greater hepatic mitochondrial respiration and reduced H2O2 emission). Despite evidence that estrogen
Autor:
Alec B. Chaves, Edwin R. Miranda, Jacob T. Mey, Brian K. Blackburn, Kelly N. Z. Fuller, Blaise Stearns, Andrew Ludlow, David L. Williamson, Joseph A. Houmard, Jacob M. Haus
Publikováno v:
J Appl Physiol (1985)
Thioredoxin-interacting protein (TXNIP) negatively effects the redox state and growth signaling via its interactions with thioredoxin (TRX) and regulated in development and DNA damage response 1 (REDD1), respectively. TXNIP expression is downregulate
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
Although there is evidence for metabolic dysfunction and chronic inflammation in Alzheimer’s disease (AD), circulating levels of soluble receptor for advanced glycation end products (sRAGE) and the receptor for advanced glycation end products (RAGE
Externí odkaz:
https://doaj.org/article/93d84389b27d4547bad7d9521a4f901a
Autor:
Kelly N. Z. Fuller, Colin S. McCoin, Harrison Stierwalt, Julie Allen, Shivam Gandhi, Christopher G. R. Perry, Purevsuren Jambal, Kartik Shankar, John P. Thyfault
Publikováno v:
The Journal of physiologyReferences. 600(24)
Compared to age-matched men, pre-menopausal women show greater resilience against cardiovascular disease (CVD), hepatic steatosis, diabetes and obesity - findings that are widely attributed to oestrogen. However, meta-analysis data suggest that curre
Autor:
Claire J. Houchen, Michael A. Choi, Kelly N. Z. Fuller, Alex T. Von Schulze, Colin S. McCoin, John P. Thyfault
Publikováno v:
Am J Physiol Endocrinol Metab
We recently reported that compared with males, female mice have increased hepatic mitochondrial respiratory capacity and are protected against high-fat diet-induced steatosis. Here, we sought to determine the role of estrogen in hepatic mitochondrial
Autor:
Kelly N. Z. Fuller, Julie Allen, Colin S. McCoin, Devin C. Koestler, Shelby Bell-Glenn, John P. Thyfault, Gerald W. Dorn
Publikováno v:
J Appl Physiol (1985)
Both lipid oversupply and poor mitochondrial function (low respiration and elevated H(2)O(2) emission) have been implicated in the development of hepatic steatosis and liver injury. Mitophagy, the targeted degradation of low-functioning mitochondria,
Autor:
Kartik Shankar, Alex T. Von Schulze, John P. Thyfault, Devin C. Koestler, Claire J. Houchen, Julie Allen, Qing Xia, Gerald W. Dorn nd, E. Matthew Morris, Adrianna Maurer, Kelly N. Z. Fuller, Colin S. McCoin
Publikováno v:
Am J Physiol Endocrinol Metab
The impact of sexual dimorphism and mitophagy on hepatic mitochondrial adaptations during the treatment of steatosis with physical activity are largely unknown. Here, we tested if deficiencies in liver-specific peroxisome proliferative activated-rece
Mild Cognitive Impairment and Donepezil Impact Mitochondrial Respiratory Capacity in Skeletal Muscle
Autor:
John P. Thyfault, Palash Sharma, Jonathan D. Mahnken, Jeffrey M. Burns, Colin S. McCoin, Xiaowan Wang, Russell H. Swerdlow, Eric D. Vidoni, Kartik Shankar, Casey S. John, Zachary D. Green, Heather M. Wilkins, Jill K. Morris, Kelly N. Z. Fuller
Publikováno v:
Function (Oxford, England)
Alzheimer's Disease (ad) associates with insulin resistance and low aerobic capacity, suggestive of impaired skeletal muscle mitochondrial function. However, this has not been directly measured in AD. This study ( n = 50) compared muscle mitochondria
Autor:
John P. Thyfault, Kartik Shankar, Alex T. Von Schulze, Kelly N. Z. Fuller, Colin S. McCoin, Julie Allen, Josh Miller, Edziu Franczak, Fengyan Deng, Wen-Xing Ding, Paige C. Geiger
Publikováno v:
Function (Oxford, England). 2(2)
Nonacholic fatty liver disease, or hepatic steatosis, is the most common liver disorder affecting the western world and currently has no pharmacologic cure. Thus, many investigations have focused on alternative strategies to treat or prevent hepatic