Výsledky vyhledávání - "N A, Egolina"

[Oxidative stress, rRNA genes, and antioxidant enzymes in pathogenesis of schizophrenia and autism: modeling and clinical advices]

Autor: L N, Porokhovnik, V P, Pasekov, N A, Egolina, T G, Tsvetkova, N V, Kosiakova, N L, Gorbachevskaia, N K, Sukhotina, G V, Kozlovskaia, A B, Sorokin, N Iu, Korovina, N A, Liapunova

Publikováno v: Zhurnal obshchei biologii. 74(5)

Ribosomal genes (RG), or genes for rRNA, are represented by multiple tandem repeats in eukaryotic genomes, and just a part of them is transcriptionally active. The quantity of active copies is a stable genome feature which determines the cell's capab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e41b257c73587debb04f6e24993f37b
https://pubmed.ncbi.nlm.nih.gov/25438566

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[Cluster size polymorphism of active human ribosomal genes and simulation of the conditions of its stability through generations]

Autor: L N, Porokhovnik, V V, Viktorov, N A, Egolina, T G, Tsvetkova, N A, Lipunova

Publikováno v: Genetika. 47(12)

Based on selective silver nitrate staining of active ribosomal gene (AcRG) clusters in nucleolus organizer regions (NORs) of human metaphase chromosomes, a technique was developed earlier to estimate the AcRG dosage in individual genomes as a sum of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60ee7d7cfa168883ff61e4981e51815d
https://pubmed.ncbi.nlm.nih.gov/22384695

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[CpG-DNA inhibits cell reactions accompanied with the development of the adaptive response in human lymphocytes after low-dose X-ray exposure]

Autor: A V, Ermakov, M S, Kon'kova, S V, Kostiuk, E A, Kalashnikova, S N, Kokarovtseva, N A, Egolina, N N, Veĭko

Publikováno v: Radiatsionnaia biologiia, radioecologiia. 49(1)

The lymphocytes of peripheral blood of healthy donors were influenced by X-ray radiation (10 cGy) or a fragments of the transcribed region of rDNA (TRrDNA) transmitted to the incubation medium of non-irradiated cells. Both factors induced transpositi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8bb3af912baaa6798b626d5ac6b40dba
https://pubmed.ncbi.nlm.nih.gov/19368319

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[Stress signaling between human lymphocytes after induction of bystander effect by exposure to ionizing radiation in adaptive doses]

Autor: A V, Ermakov, S V, Kostiuk, N A, Egolina, E A, Kalashnikova, S N, Kokarovtseva, E M, Malinovskaia, N N, Veĭko

Publikováno v: Radiatsionnaia biologiia, radioecologiia. 47(6)

We previously reported that the consequence of human lymphocytes irradiation by the adaptive doses (X-rays, 10 cGy) was a transposition of the homologous chromosome loci in the cell nucleus (FISH method); this phenomenon was mediated by the increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bab3f0f4a0b39fe8a5f3b92c168130ed
https://pubmed.ncbi.nlm.nih.gov/18380323

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[The DNA fragments obtained from the culture media exposed to adaptive doses of the ionizing radiation as factors of stress signaling between lymphocytes and bystander cells]

Autor: A V, Ermakov, S V, Kostiuk, N A, Egolina, E M, Malinovskaia, N N, Veĭko, D M, Spitkovskiĭ

Publikováno v: Radiatsionnaia biologiia, radioecologiia. 47(2)

At the initial stages of an adaptive response the transposition of the homologous chromosome loci from the peripheral parts of the nucleus and their approach happens. It is necessary for the repair of DNA double strand breaks in the process of the ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2c9f3a9d9909172e20fa44328ebbfed
https://pubmed.ncbi.nlm.nih.gov/17571721

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[Early and late responses to oxidative stress in human dermal fibroblasts of healthy donors and rheumatoid arthritis patients. Relationship between the cell death rate and the genomic dosage of active ribosomal genes]

Autor: N N, Beĭko, S M, Terekhov, N O, Shubaeva, T D, Simirnova, S M, Ivanova, N A, Egolina, T G, Tsvetkova, D M, Spitkovskiĭ, N A, Liapunova

Publikováno v: Molekuliarnaia biologiia. 39(2)

A study was made of the effect of the oxidizing agent potassium chromate (K2CrO4, PC) on cultured dermal fibroblasts of a healthy donor and three patients with rheumatoid arthritis (RA). Characteristics of the rRNA gene (RG) complex-RG copy number, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eb0dab1df8f5575c132f33ef0afc52e4
https://pubmed.ncbi.nlm.nih.gov/15856950

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[Activation of total and ribosomal RNA transcription under adapting doses of ionizing radiation inducing displacement of chromosome loci in human G0-lymphocyte]

Autor: N N, Veĭko, A V, Ermakov, N A, Egolina, N A, Liapunova, D M, Spitkovskiĭ

Publikováno v: Radiatsionnaia biologiia, radioecologiia. 44(5)

As we demonstrated earlier, the adapting X-ray doses (3 and 10 cGy) induced movement of chromosome centromeric loci in G0-lymphocyte nuclei. In the present study we investigated the influence of X-rays with 3 and 10 cGy doses on the content of total,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::659d3b3b6b842f8e2b712fb42762aee7
https://pubmed.ncbi.nlm.nih.gov/15571036

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[Quantitative analysis of repetitive sequences in human genomic DNA and detection of an elevated ribosomal repeat copy number in patients with schizophrenia (the results of molecular and cytogenetic analysis)]

Autor: N N, Veĭko, N A, Egolina, G G, Radzivil, S D, Nurbaev, N V, Kosiakova, N O, Shubaeva, N A, Liapunova

Publikováno v: Molekuliarnaia biologiia. 37(3)

A modified version of quantitating repetitive sequences in genomic DNA was developed to allow comparisons for numerous individual genomes and simultaneous analysis of several sequences in each DNA specimen. The relative genomic content of ribosomal r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a117fd47f8da98293f6efcbaaf8f715a
https://pubmed.ncbi.nlm.nih.gov/12815948

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