Výsledky vyhledávání - "N A, Darmani"

Akademický článek

The HCN Channel Blocker ZD7288 Induces Emesis in the Least Shrew (Cryptotis parva)

Autor: W. Zhong, N. A. Darmani

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Subtypes (1–4) of the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are widely expressed in the central and peripheral nervous systems, as well as the cells of smooth muscles in many organs. They mainly serve to regulate cellul

Externí odkaz: https://doaj.org/article/c81000167fdb4144bd4c08c3ca874248

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Role of PI3K/Akt/GSK-3 Pathway in Emesis and Potential New Antiemetics

Autor: W Zhong, N A Darmani

Publikováno v: Journal of cellular signaling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbd9781ea290345b6f0ab7e503195d2
https://doi.org/10.33696/signaling.1.024

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Intracellular emetic signaling cascades by which the selective neurokinin type 1 receptor (NK

Autor: W, Zhong, S, Chebolu, N A, Darmani

Publikováno v: Neurochemistry international. 122

To characterize mechanisms involved in neurokinin type 1 receptor (NK(1)R)-mediated emesis, we investigated the brainstem emetic signaling pathways following treating least shrews with the selective NK(1)R agonist GR73632. In addition to episodes of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6781654a6a7d703c84314dec90c58871
https://pubmed.ncbi.nlm.nih.gov/30453005

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Involvement of the cannabimimetic compound, N-palmitoylethanolamine, in inflammatory and neuropathic conditions: A review of the available pre-clinical data, and first human studies

Autor: N. A. Darmani, A. A. Izzo, B. Degenhardt, M. Valenti, G. Scaglione, R. Capasso, I. Sorrentini, V. Di Marzo

Publikováno v: Neuropharmacology 48 (2005): 1154–1163.
info:cnr-pdr/source/autori:N. A. Darmani, A. A. Izzo, B. Degenhardt, M. Valenti, G. Scaglione, R. Capasso, I. Sorrentini and V. Di Marzo/titolo:Involvement of the cannabimimetic compound, N-palmitoylethanolamine, in inflammatory and neuropathic conditions: A review of the available pre-clinical data, and first human studies/doi:/rivista:Neuropharmacology/anno:2005/pagina_da:1154/pagina_a:1163/intervallo_pagine:1154–1163/volume:48

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::25198dd649b0a659bfbdc849ab1eb0b8
http://www.cnr.it/prodotto/i/15284

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Anatomic and physiologic reference values in least shrews (Cryptotis parva)

Autor: O B, Mock, S W, Casteel, N A, Darmani, J H, Shaddy, C, Besch-Williford, L C, Towns

Publikováno v: Comparative medicine. 51(6)

The least shrew is an established animal model for reproductive and pharmacologic research. Biologic reference data are needed to assess animal health status and provide a rationale for use of novel statistical programs to evaluate the effects of ora

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aff6c0bb2cbc4b21ca3f654310ecca67
https://pubmed.ncbi.nlm.nih.gov/11924816

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Long-term sequential determination of behavioral ontogeny of 5-HT1A and 5-HT2 receptor functions in the rat

Autor: N A, Darmani, B, Ahmad

Publikováno v: The Journal of pharmacology and experimental therapeutics. 288(1)

Activation of 5-hydroxytryptamine1A (5-HT1A) receptors in rats produces hypothermia and a number of behaviors [hindleg abduction (HLA), lateral head-weaving (LHW), forepaw treading (FPT), flat body posture (FBP), rollover (RO), tremor (T), and straub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05ecb013feabd29fed13c9efd2a86c61
https://pubmed.ncbi.nlm.nih.gov/9862777

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The silent and selective 5-HT1A antagonist, WAY 100635, produces via an indirect mechanism, a 5-HT2A receptor-mediated behaviour in mice during the day but not at night. Short communication

Autor: N A, Darmani

Publikováno v: Journal of neural transmission (Vienna, Austria : 1996). 105(6-7)

The head-twitch response (HTR) in rodents is considered to be a functional index for the activation of 5-HT2A receptors. Intraperitoneal administration of the silent and selective 5-HT1A receptor antagonist, WAY 100635, produced the HTR in mice in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd42515b623236ee0b879fac627ff5bd
https://pubmed.ncbi.nlm.nih.gov/9826108

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Behavioral evidence for differential adaptation of the serotonergic system after acute and chronic treatment with (+/- )-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) or ketanserin

Autor: N A, Darmani, B R, Martin, R A, Glennon

Publikováno v: The Journal of pharmacology and experimental therapeutics. 262(2)

The 5-hydroxytryptamine (5-HT)2 agonist (+/- )-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and antagonist ketanserin were evaluated for acute and chronic effects on the 5-HT2 receptor-mediated head-twitch response (HTR) in mice. A single dose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::591affd5ee14e79a8f7ff1d2b69f7d2c
https://pubmed.ncbi.nlm.nih.gov/1501117

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Acute effects of beclamide on brain regional monoamine concentrations, their metabolites and radioligand binding studies

Autor: N. A. Darmani, Robert David Edmund Sewell, Paul J. Nicholls

Publikováno v: Scopus-Elsevier

The effects of beclamide on regional brain monoamine levels and radioligand binding have been studied in rats. One hour oral pre-treatment with beclamide (400 mg kg−1) increased rat striatal dopamine turnover by increasing the levels of its major m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508333656a3c44efed2874ee244daf99
https://pubmed.ncbi.nlm.nih.gov/1717674

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