Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Autor: Wyllie, Susan, Brand, Stephen, Thomas, Michael, De Rycker, Manu, Chung, Chun-wa, Pena, Imanol, Bingham, Ryan P., Bueren-Calabuig, Juan A., Cantizani, Juan, Cebrian, David, Craggs, Peter D., Ferguson, Liam, Goswami, Panchali, Hobrath, Judith, Howe, Jonathan, Jeacock, Laura, Ko, Eun-Jung, Korczynska, Justyna, MacLean, Lorna, Manthri, Sujatha, Martinez, Maria S., Mata-Cantero, Lydia, Moniz, Sonia, Nühs, Andrea, Osuna-Cabello, Maria, Pinto, Erika, Riley, Jennifer, Robinson, Sharon, Rowland, Paul, Simeons, Frederick R. C., Shishikura, Yoko, Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Gaza, Elisabet Viayna, Wall, Richard J., Zuccotto, Fabio, Horn, David, Ferguson, Michael A. J., Fairlamb, Alan H., Fiandor, Jose M., Martin, Julio, Gray, David W., Miles, Timothy J., Gilbert, Ian H., Read, Kevin D., Marco, Maria, Wyatt, Paul G.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2019 May 01. 116(19), 9318-9323.

Externí odkaz: https://www.jstor.org/stable/26705116

Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity.

Autor: Nühs, Andrea¹, De Rycker, Manu¹, Manthri, Sujatha¹, Comer, Eamon², Scherer, Christina A.², Schreiber, Stuart L.², Ioset, Jean-Robert³, Gray, David W.¹ d.w.gray@dundee.ac.uk

Publikováno v: PLoS Neglected Tropical Diseases. 9/25/2015, Vol. 9 Issue 9, p1-17. 17p.

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A novel marker, ARM58, confers antimony resistance to Leishmania spp.

Autor: Nühs A; Bernhard Nocht Institute for Tropical Medicine, D20359 Hamburg, Germany., Schäfer C; Bernhard Nocht Institute for Tropical Medicine, D20359 Hamburg, Germany., Zander D; Bernhard Nocht Institute for Tropical Medicine, D20359 Hamburg, Germany., Trübe L; Bernhard Nocht Institute for Tropical Medicine, D20359 Hamburg, Germany., Tejera Nevado P; Bernhard Nocht Institute for Tropical Medicine, D20359 Hamburg, Germany., Schmidt S; Bernhard Nocht Institute for Tropical Medicine, D20359 Hamburg, Germany., Arevalo J; Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru., Adaui V; Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru., Maes L; Department of Biomedical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium., Dujardin JC; Instituut voor Tropische Geneeskunde, Antwerp, Belgium ; Department of Biomedical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium., Clos J; Bernhard Nocht Institute for Tropical Medicine, D20359 Hamburg, Germany.

Publikováno v: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2013 Dec 06; Vol. 4 (1), pp. 37-47. Date of Electronic Publication: 2013 Dec 06 (Print Publication: 2014).