Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Núria Reig"'
Autor:
Ricardo Sant’Anna, Pablo Gallego, Lei Z. Robinson, Alda Pereira-Henriques, Nelson Ferreira, Francisca Pinheiro, Sebastian Esperante, Irantzu Pallares, Oscar Huertas, Maria Rosário Almeida, Natàlia Reixach, Raul Insa, Adrian Velazquez-Campoy, David Reverter, Núria Reig, Salvador Ventura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/e01ea5c5ac0a4bd48c5c5662836b01fd
Autor:
Ricardo Sant'Anna, Pablo Gallego, Lei Z. Robinson, Alda Pereira-Henriques, Nelson Ferreira, Francisca Pinheiro, Sebastian Esperante, Irantzu Pallares, Oscar Huertas, Maria Rosário Almeida, Natàlia Reixach, Raul Insa, Adrian Velazquez-Campoy, David Reverter, Núria Reig, Salvador Ventura
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Misfolding of transthyretin can cause amyloid aggregation disorders that can be treated by stabilizing the tetrameric form with tafamidis. Here the authors show that tolcapone, a drug already FDA-approved for Parkinson disease, has strong transthyret
Externí odkaz:
https://doaj.org/article/837ff0b26f1b42a594f1b539d90bcb7c
Autor:
Josep Gamez, Matilde Calopa, Esteban Muñoz, Aileen Ferré, Oscar Huertas, Kevin McAllister, Núria Reig, Catherine Scart‐Grès, Raúl Insa, Jaime Kulisevsky
Publikováno v:
British journal of clinical pharmacologyREFERENCES.
The study's aim is to investigate the efficacy and safety of SOM3355 (bevantolol hydrochloride), a βA randomized, placebo-controlled proof-of-concept study was performed in 32 HD patients allocated to 2 arms of 4 sequential 6-week periods each. Pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4612ae6b2eca528af7cdc517d8b7bd3a
https://pubmed.ncbi.nlm.nih.gov/36494329
https://pubmed.ncbi.nlm.nih.gov/36494329
Autor:
Seri Jo, Luca Signorile, Suwon Kim, Mi-Sun Kim, Oscar Huertas, Raúl Insa, Núria Reig, Dong Hae Shin
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6468
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) wreaked havoc all over the world. Although vaccines for the disease have recently become available and started to be administer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580e7a4c050bd1efcb1351cfa94afea5
Autor:
Oscar Huertas, Aileen Ferré, Kevin McAllister, Jaime Kulisevsky, Josep Gamez, Núria Reig, Raul Insa, Catherine Scart-Grès, Esteban Muñoz, Matilde Calopa
Publikováno v:
F: Clinical studies: case reports, observational studies and trials.
Background SOM3355 (bevantolol hydrochloride), a β1-adrenoceptor blocker used in hypertension, was identified as a vesicular monoamine transporter type 2 (VMAT2) inhibitor by artificial intelligence screening, and then selected by in vitro functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e684082dde644a3457b6b244fbaf99
https://doi.org/10.1136/jnnp-2021-ehdn.83
https://doi.org/10.1136/jnnp-2021-ehdn.83
Autor:
Maria Salvado, Núria Reig, Carles Casasnovas, Raul Insa, Josep Gamez, Ricard Rojas-García, Pilar Suñé
Publikováno v:
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Objective: To assess the transthyretin (TTR) stabilization activity of tolcapone (SOM0226) in patients with hereditary ATTR amyloidosis, asymptomatic carriers and healthy volunteers. Methods: A phase IIa proof-of-concept trial included two phases sep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e46d25e12124fd6a9915904cf73d8a
https://doi.org/10.1080/13506129.2019.1597702
https://doi.org/10.1080/13506129.2019.1597702
Autor:
Josep, Gamez, María, Salvadó, Núria, Reig, Pilar, Suñé, Carles, Casasnovas, Ricard, Rojas-Garcia, Raúl, Insa
Publikováno v:
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 26(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4531ed019393ab8970875354090d71b1
https://pubmed.ncbi.nlm.nih.gov/31119947
https://pubmed.ncbi.nlm.nih.gov/31119947
Autor:
Dong-Hae Shin, Núria Reig
Publikováno v:
Open Forum Infectious Diseases
Background The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is seriously impacting health and economies all over the world. With more than 8 million diagnosed cases and close t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d671f3a742ce85ebb39e11f70eb2e33d
https://doi.org/10.1093/ofid/ofaa439.754
https://doi.org/10.1093/ofid/ofaa439.754
Autor:
Natàlia Reixach, Salvador Ventura, Raul Insa, Ricardo Sant'Anna, Oscar Huertas, David Reverter, Adrián Velázquez-Campoy, Lei Z. Robinson, Sebastian Esperante, Nelson Ferreira, Maria Rosário Almeida, Pablo Gallego, Alda Pereira-Henriques, Irantzu Pallarès, Francisca Pinheiro, Núria Reig
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications
13 pags, 6 figs, 1 tab. -- Supplementary information is available at the Publisher's web
Transthyretin (TTR) is a plasma homotetrameric protein implicated in fatal systemic amyloidoses. TTR tetramer dissociation precedes pathological TTR aggrega
Transthyretin (TTR) is a plasma homotetrameric protein implicated in fatal systemic amyloidoses. TTR tetramer dissociation precedes pathological TTR aggrega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64234fcfaf7f7adcb8d807ac4da4df1f
http://hdl.handle.net/10261/255695
http://hdl.handle.net/10261/255695
Autor:
César del Rio, Núria Reig, Manuel Palacín, Josep Lluís Gelpí, David Torrents, Peter J. F. Henderson, Stephen A. Baldwin, Hao Xie, Dimitrios Fotiadis, Merce Ratera, Antonio Zorzano, Fabio Casagrande
Publikováno v:
Journal of Biological Chemistry. 282:13270-13281
We have identified YkbA from Bacillus subtilis as a novel member of the L-amino acid transporter (LAT) family of amino acid transporters. The protein is approximately 30% identical in amino acid sequence to the light subunits of human heteromeric ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::273f6d417786a9a24a73c91c3faf7efe
https://doi.org/10.1074/jbc.m610695200
https://doi.org/10.1074/jbc.m610695200