Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Núria DeGregorio-Rocasolano"'
Autor:
Carlos Castaño, Marc Melià-Sorolla, Alexia García-Serran, Núria DeGregorio-Rocasolano, Maria Rosa García-Sort, María Hernandez-Pérez, Adrián Valls-Carbó, Osvaldo Pino, Jordi Grífols, Alba Iruela-Sánchez, Alicia Palomar-García, Josep Puig, Octavi Martí-Sistac, Antoni Dávalos, Teresa Gasull
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
The need for advances in the management/treatment options for ischemic stroke patients requires that upcoming preclinical research uses animals with more human-like brain characteristics. The porcine brain is considered appropriate, although the pres
Externí odkaz:
https://doaj.org/article/c21de8f593ff4c549dea247127c76ba2
Autor:
Alexia García-Serran, Jesús Ordoño, Núria DeGregorio-Rocasolano, Marc Melià-Sorolla, Karla Odendaal, Octavi Martí-Sistac, Teresa Gasull
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1945 (2023)
We have previously demonstrated that the post-stroke administration of iron-free transferrin (apotransferrin, ATf) is beneficial in different models of ischemic stroke (IS) through the inhibition of the neuronal uptake of pro-oxidant iron. In the pre
Externí odkaz:
https://doaj.org/article/cc9117fbdea742908262e43c0ddfd323
Autor:
Mònica Millán, Núria DeGregorio-Rocasolano, Natàlia Pérez de la Ossa, Sílvia Reverté, Joan Costa, Pilar Giner, Yolanda Silva, Tomás Sobrino, Manuel Rodríguez-Yáñez, Florentino Nombela, Francisco Campos, Joaquín Serena, José Vivancos, Octavi Martí-Sistac, Jordi Cortés, Antoni Dávalos, Teresa Gasull
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1270 (2021)
A role of iron as a target to prevent stroke-induced neurodegeneration has been recently revisited due to new evidence showing that ferroptosis inhibitors are protective in experimental ischemic stroke and might be therapeutic in other neurodegenerat
Externí odkaz:
https://doaj.org/article/4d8db7d59d7d4d119ea5ec8697cadfdb
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
In general, iron represents a double-edged sword in metabolism in most tissues, especially in the brain. Although the high metabolic demands of brain cells require iron as a redox-active metal for ATP-producing enzymes, the brain is highly vulnerable
Externí odkaz:
https://doaj.org/article/bdab2dc43de64d5780db4fcecd586f2a
Autor:
Núria DeGregorio-Rocasolano, Verónica Guirao, Jovita Ponce, Marc Melià-Sorolla, Alicia Aliena-Valero, Alexia García-Serran, Juan B. Salom, Antoni Dávalos, Octavi Martí-Sistac, Teresa Gasull
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1202 (2020)
Death-associated protein kinase 1 (DAPK1) is a pleiotropic hub of a number of networked distributed intracellular processes. Among them, DAPK1 is known to interact with the excitotoxicity driver NMDA receptor (NMDAR), and in sudden pathophysiological
Externí odkaz:
https://doaj.org/article/2fd2397e33f04872804d7f4a2f1658b2
Autor:
Nuria DeGregorio-Rocasolano, Octavi Martí-Sistac, Jovita Ponce, María Castelló-Ruiz, Mònica Millán, Verónica Guirao, Isaac García-Yébenes, Juan B. Salom, Pedro Ramos-Cabrer, Enrique Alborch, Ignacio Lizasoain, José Castillo, Antoni Dávalos, Teresa Gasull
Publikováno v:
Redox Biology, Vol 15, Iss C, Pp 143-158 (2018)
Despite transferrin being the main circulating carrier of iron in body fluids, and iron overload conditions being known to worsen stroke outcome through reactive oxygen species (ROS)-induced damage, the contribution of blood transferrin saturation (T
Externí odkaz:
https://doaj.org/article/facd8b78a4874d8e865b236e82696fcb