Multimodal evaluation of drug antibacterial activity reveals cinnamaldehyde analog anti-biofilm effects against Haemophilus influenzae

Autor: Javier Asensio-López, María Lázaro-Díez, Tania M. Hernández-Cruz, Núria Blanco-Cabra, Ioritz Sorzabal-Bellido, Eva M. Arroyo-Urea, Elena Buetas, Ana González-Paredes, Carlos Ortiz de Solórzano, Saioa Burgui, Eduard Torrents, María Monteserín, Junkal Garmendia

Publikováno v: Biofilm, Vol 7, Iss , Pp 100178- (2024)

Biofilm formation by the pathobiont Haemophilus influenzae is associated with human nasopharynx colonization, otitis media in children, and chronic respiratory infections in adults suffering from chronic respiratory diseases such as chronic obstructi

Externí odkaz: https://doaj.org/article/e731dcb5f85e4c60a48e1793a496e037

Neutralization of ionic interactions by dextran-based single-chain nanoparticles improves tobramycin diffusion into a mature biofilm

Autor: Núria Blanco-Cabra, Julie Movellan, Marco Marradi, Raquel Gracia, Cristian Salvador, Damien Dupin, Iraida Loinaz, Eduard Torrents

Publikováno v: npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-12 (2022)

Abstract The extracellular matrix protects biofilm cells by reducing diffusion of antimicrobials. Tobramycin is an antibiotic used extensively to treat P. aeruginosa biofilms, but it is sequestered in the biofilm periphery by the extracellular negati

Externí odkaz: https://doaj.org/article/6b62668d3be848169689f29e63fda04a

A new BiofilmChip device for testing biofilm formation and antibiotic susceptibility

Autor: Núria Blanco-Cabra, Maria José López-Martínez, Betsy Verónica Arévalo-Jaimes, María Teresa Martin-Gómez, Josep Samitier, Eduard Torrents

Publikováno v: npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-9 (2021)

Abstract Currently, three major circumstances threaten the management of bacterial infections: increasing antimicrobial resistance, expansion of chronic biofilm-associated infections, and lack of an appropriate approach to treat them. To date, the de

Externí odkaz: https://doaj.org/article/758f4027175b472db225f40d78bb7777

Aerobic Vitamin B12 Biosynthesis Is Essential for Pseudomonas aeruginosa Class II Ribonucleotide Reductase Activity During Planktonic and Biofilm Growth

Autor: Anna Crespo, Núria Blanco-Cabra, Eduard Torrents

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

Pseudomonas aeruginosa is a major pathogenic bacterium in chronic infections and is a model organism for studying biofilms. P. aeruginosa is considered an aerobic bacterium, but in the presence of nitrate, it also grows in anaerobic conditions. Oxyge

Externí odkaz: https://doaj.org/article/8c627860571e467f87e32eeff24f6bd6

Drug-Free Enzyme-Based Bactericidal Nanomotors against Pathogenic Bacteria

Autor: Ana C. Hortelão, Samuel Sanchez, Núria Blanco-Cabra, Diana Vilela, Eduard Torrents, Ander Eguskiza

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
E-Prints Complutense. Archivo Institucional de la UCM
instname
ACS Applied Materials & Interfaces

The low efficacy of current conventional treatments for bacterial infections increases mortality rates worldwide. To alleviate this global health problem, we propose drug-free enzyme- based nanomotors for the treatment of bacterial urinary-tract infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5289a58dd2dfff12a36098a060cbedec
https://doi.org/10.1021/acsami.1c00986