Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Núria, de la Iglesia"'
Autor:
Marta Moreno, Leire Pedrosa, Laia Paré, Estela Pineda, Leire Bejarano, Josefina Martínez, Veerakumar Balasubramaniyan, Ravesanker Ezhilarasan, Naveen Kallarackal, Sung-Hak Kim, Jia Wang, Alessandra Audia, Siobhan Conroy, Mercedes Marin, Teresa Ribalta, Teresa Pujol, Antoni Herreros, Avelina Tortosa, Helena Mira, Marta M. Alonso, Candelaria Gómez-Manzano, Francesc Graus, Erik P. Sulman, Xianhua Piao, Ichiro Nakano, Aleix Prat, Krishna P. Bhat, Núria de la Iglesia
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2183-2197 (2017)
A mesenchymal transition occurs both during the natural evolution of glioblastoma (GBM) and in response to therapy. Here, we report that the adhesion G-protein-coupled receptor, GPR56/ADGRG1, inhibits GBM mesenchymal differentiation and radioresistan
Externí odkaz:
https://doaj.org/article/a26249bc3090411b9bb7ed6f862f62c4
Autor:
Elisabetta Stanzani, Leire Pedrosa, Guillaume Bourmeau, Oceane Anezo, Aleix Noguera-Castells, Anna Esteve-Codina, Lorena Passoni, Michela Matteoli, Núria de la Iglesia, Giorgio Seano, Fina Martínez-Soler, Avelina Tortosa
Publikováno v:
Cancers, Vol 13, Iss 12, p 3055 (2021)
Therapeutic resistance after multimodal therapy is the most relevant cause of glioblastoma (GBM) recurrence. Extensive cellular heterogeneity, mainly driven by the presence of GBM stem-like cells (GSCs), strongly correlates with patients’ prognosis
Externí odkaz:
https://doaj.org/article/642f138a3d814a63ae49e04dd318c8cf
Autor:
Marta Moreno, Virginia Fernández, Josep M. Monllau, Víctor Borrell, Carles Lerin, Núria de la Iglesia
Publikováno v:
Stem Cell Reports, Vol 5, Iss 2, Pp 157-165 (2015)
Neural stem cells (NSCs) reside in a hypoxic microenvironment within the brain. However, the crucial transcription factors (TFs) that regulate NSC biology under physiologic hypoxia are poorly understood. Here we have performed gene set enrichment ana
Externí odkaz:
https://doaj.org/article/48b6890f17744eb79fe824039973c9c7
Autor:
Laura Oleaga, J. Marruecos, Cristina Carrato, Marta Gut, Marta Domenech, Beatriz Bellosillo, Jordi Craven-Bartle, Mar Mallo, Angels Camins, Maria Martinez-Garcia, Anna Esteve-Codina, Ana M. Muñoz-Mármol, I. Valduvieco, Carmen Balana, Anna Martínez-Cardús, Avelina Tortosa, Salvador Villà, Sonia Del Barco, Miquel Gil-Gil, Sira Domenech, Estela Pineda, Marc Dabad, Núria de la Iglesia, Josep Puig, Anna Esteve, Oscar Gallego, Jaume Capellades, Francesc Alameda, Cristian de Quintana-Schmidt, Oriol Arpí, Teresa Pujol
Purpose: Glioblastoma is the most aggressive brain tumor in adults and has few therapeutic options. The study of molecular subtype classifications may lead to improved prognostic classification and identification of new therapeutic targets. The Cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7797975c07f87809d336dcf0c7ceea04
http://hdl.handle.net/10230/45651
http://hdl.handle.net/10230/45651
Autor:
Lorena Passoni, Aleix Noguera-Castells, Núria de la Iglesia, Michela Matteoli, Leire Pedrosa, Océane Anezo, Avelina Tortosa, Elisabetta Stanzani, Anna Esteve-Codina, Guillaume Bourmeau, Fina Martínez-Soler, Giorgio Seano
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Cancers
Cancers, MDPI, 2021, 13 (12), pp.3055. ⟨10.3390/cancers13123055⟩
Cancers, 2021, 13 (12), pp.3055. ⟨10.3390/cancers13123055⟩
Cancers, Vol 13, Iss 3055, p 3055 (2021)
Volume 13
Issue 12
Universidad de Barcelona
Cancers
Cancers, MDPI, 2021, 13 (12), pp.3055. ⟨10.3390/cancers13123055⟩
Cancers, 2021, 13 (12), pp.3055. ⟨10.3390/cancers13123055⟩
Cancers, Vol 13, Iss 3055, p 3055 (2021)
Volume 13
Issue 12
Simple Summary Glioblastoma stem-like cells (GSCs) are responsible for most of the malignant characteristics of glioblastoma, including therapeutic resistance, tumour recurrence, and tumour cellular heterogeneity. Therefore, increased understanding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b4dff2d5676f7c564c485e4141aeb2
http://hdl.handle.net/2445/179014
http://hdl.handle.net/2445/179014
Autor:
Oscar Gallego, Julie Marie Blanc, Josep Puig, Maria Martinez-Garcia, Silvia Menendez, Ana M. Muñoz-Mármol, Mar Mallo, Anna Esteve-Codina, Jordi Craven-Bartle, Ivan Archilla, Cristina Carrato, Jaume Capellades, Anna Esteve, Iban Aldecoa, Carlos Mesia, Rafael Fuentes, Núria de la Iglesia, Beatriz Bellosillo, Sonia Del Barco, Silvia Bagué, Carmen Balana, Ainhoa Hernandez, Francesc Alameda, Teresa Ribalta, Raquel Lopez-Martos, Oriol Arpí, Montserrat Arumi, Noemi Vidal, Marta Gut, Estela Pineda
Publikováno v:
Clinical Cancer Research
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
CLINICAL CANCER RESEARCH
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut dInvestigació Biomèdica Sant Pau (IIB Sant Pau)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
CLINICAL CANCER RESEARCH
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut dInvestigació Biomèdica Sant Pau (IIB Sant Pau)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Purpose: Molecular subtype classifications in glioblastoma may detect therapy sensitivities. IHC would potentially allow the identification of molecular subtypes in routine clinical practice. Experimental Design: Formalin-fixed, paraffin-embedded tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a808c0a9c0759340ad8b201493ebd8
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4935
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4935
Autor:
Krishna P. Bhat, Antoni Herreros, Candelaria Gomez-Manzano, Teresa Pujol, Leire Pedrosa, Xianhua Piao, Laia Paré, Erik P. Sulman, Jia Wang, Marta Moreno, Marta M. Alonso, Aleix Prat, Veerakumar Balasubramaniyan, Naveen Kallarackal, Josefina Martínez, Mercedes Marin, Ravesanker Ezhilarasan, Núria de la Iglesia, Teresa Ribalta, Siobhan Conroy, Sung Hak Kim, Helena Mira, Ichiro Nakano, Leire Bejarano, Estela Pineda, Alessandra Audia, Francesc Graus, Avelina Tortosa
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2183-2197 (2017)
Cell reports, 21(8), 2183-2197. CELL PRESS
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
Cell reports, 21(8), 2183-2197. CELL PRESS
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
15 páginas, 7 figuras. Contiene información suplementaria en l aversión online.
A mesenchymal transition occurs both during the natural evolution of glioblastoma (GBM) and in response to therapy. Here, we report that the adhesion G-protein-co
A mesenchymal transition occurs both during the natural evolution of glioblastoma (GBM) and in response to therapy. Here, we report that the adhesion G-protein-co
Autor:
Elisabetta, Stanzani, Fina, Martínez-Soler, Teresa Martín, Mateos, Noemi, Vidal, Alberto, Villanueva, Miquel Angel, Pujana, Jordi, Serra-Musach, Núria, de la Iglesia, Pepita, Giménez-Bonafé, Avelina, Tortosa
Publikováno v:
Oncotarget
Glioblastoma (GBM) still remains an incurable disease being radiotherapy (RT) the mainstay treatment. Glioblastoma intra-tumoral heterogeneity and Glioblastoma-Initiating Cells (GICs) challenge the design of effective therapies. We investigated GICs
Autor:
Candelaria Gomez-Manzano, Francesc Graus, Veerakumar Balasubramaniyan, Xianhua Piao, Krishna P. Bhat, Ichiro Nakano, Leire Bejarano, Sung Hak Kim, Naveen Kallarackal, Ravesanker Ezhilarasan, Núria de la Iglesia, Josefina Martínez, Erik P. Sulman, Marta Moreno, Avelina Tortosa, Aleix Prat, Laia Paré, Estela Pineda
A proneural-to-mesenchymal transition (PMT) is thought to occur during natural evolution of glioblastoma (GBM) as well as in response to therapy, specifically during acquisition of radioresistance. In order to identify novel inhibitors of PMT, we sea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96545cdde5530dfd17e047d695f2bde2
https://europepmc.org/articles/PMC4639240/
https://europepmc.org/articles/PMC4639240/
Autor:
Núria de la Iglesia, KT Scougall, Anna L. Gloyn, Loranne Agius, Alex J. Lange, James Shaw, Franz M. Matschinsky, Catherine Arden, Alison H. Trainer
Publikováno v:
Diabetes. 56:1773-1782
Mutations in the glucokinase (GK) gene cause defects in blood glucose homeostasis. In some cases (V62M and G72R), the phenotype cannot be explained by altered enzyme kinetics or protein instability. We used transient and stable expression of green fl