Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Núria, Casals"'
Autor:
Sebastián Zagmutt, Paula Mera, Ismael González-García, Kevin Ibeas, María del Mar Romero, Arnaud Obri, Beatriz Martin, Anna Esteve-Codina, M. Carmen Soler-Vázquez, Marianela Bastias-Pérez, Laia Cañes, Elisabeth Augé, Carme Pelegri, Jordi Vilaplana, Xavier Ariza, Jordi García, José Martinez-González, Núria Casals, Miguel López, Richard Palmiter, Elisenda Sanz, Albert Quintana, Laura Herrero, Dolors Serra
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-26 (2023)
Highlights Fatty acid metabolism and CPT1A in AgRP neurons show marked sex-dependent differences in the control of feeding. Cpt1a gene deletion in AgRP neurons increases energy expenditure in females but not in males. CPT1A in AgRP neurons is involve
Externí odkaz:
https://doaj.org/article/9eef829aeb3f49da853bf659361e7019
Autor:
Rut Fadó, Sebastian Zagmutt, Laura Herrero, Helena Muley, Rosalía Rodríguez-Rodríguez, Huichang Bi, Dolors Serra, Núria Casals
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract There is an urgent need to identify reliable genetic biomarkers for accurate diagnosis, prognosis, and treatment of different tumor types. Described as a prognostic marker for many tumors is the neuronal protein carnitine palmitoyltransferas
Externí odkaz:
https://doaj.org/article/253d82ab8418418b819f50de3f1bcef8
Autor:
Cristina Miralpeix, Anna Fosch, Josefina Casas, Miguel Baena, Laura Herrero, Dolors Serra, Rosalía Rodríguez-Rodríguez, Núria Casals
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1260-1269 (2019)
The endocannabinoid (eCB) system regulates energy homeostasis and is linked to obesity development. However, the exact dynamic and regulation of eCBs in the hypothalamus during obesity progression remain incompletely described and understood. Our stu
Externí odkaz:
https://doaj.org/article/b12ad966019e448685f9b86ff22da17a
Publikováno v:
European Journal of Neuroscience. 57:1447-1465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35d681e269207d917398a5966393060f
https://doi.org/10.1111/ejn.15960
https://doi.org/10.1111/ejn.15960
Autor:
Xavier Roa-Mansergas, Rut Fadó, Maher Atari, Joan F. Mir, Helena Muley, Dolors Serra, Núria Casals
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Human mesenchymal stem cells (hMSCs) are widely used in regenerative medicine. In some applications, they must survive under low nutrient conditions engendered by avascularity. Strategies to improve hMSCs survival may be of high relevance in
Externí odkaz:
https://doaj.org/article/9207a62a582b4db59d770e220fde6e21
Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
Autor:
Marta Palomo-Guerrero, Rut Fadó, Maria Casas, Marta Pérez-Montero, Miguel Baena, Patrick O Helmer, José Luis Domínguez, Aina Roig, Dolors Serra, Heiko Hayen, Harald Stenmark, Camilla Raiborg, Núria Casals
Publikováno v:
eLife, Vol 8 (2019)
Anterograde transport of late endosomes or lysosomes (LE/Lys) is crucial for proper axon growth. However, the role of energetic nutrients has been poorly explored. Malonyl-CoA is a precursor of fatty acids, and its intracellular levels highly fluctua
Externí odkaz:
https://doaj.org/article/3271027ebcbb4e948ef1a81bd8c4e174
Autor:
M Carmen Soler-Vázquez, María del Mar Romero, Marijana Todorcevic, Katia Delgado, Carles Calatayud, Aleyda Benitez -Amaro, Maria Teresa La Chica Lhoëst, Paula Mera, Sebastián Zagmutt, Marianela Bastías-Pérez, Kevin Ibeas, Núria Casals, Joan Carles Escolà-Gil, Vicenta Llorente-Cortés, Antonella Consiglio, Dolors Serra, Laura Herrero
Obesity and its associated metabolic comorbidities are a rising global health and social issue, with novel therapeutic approaches urgently needed. Adipose tissue plays a key role in the regulation of energy balance and adipose tissue-derived mesenchy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3565be543d08071724089986bbd75f2
http://hdl.handle.net/20.500.12328/3685
http://hdl.handle.net/20.500.12328/3685
Autor:
Jesús Garcia-Chica, West Kristian Dizon Paraiso, Sebastián Zagmutt, Anna Fosch, Ana Cristina Reguera, Sara Alzina, Laura Sánchez-García, Shigeto Fukushima, Kazuko Toh, Núria Casals, Dolors Serra, Laura Herrero, Jordi Garcia, Kazunori Kataoka, Xavier Ariza, Sabina Quader, Rosalía Rodríguez-Rodríguez
Targeting brain lipid metabolism is a promising strategy to regulate the energy balance and fight metabolic diseases such as obesity. The development of stable platforms for selective delivery of drugs, particularly to the hypothalamus, is a challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfeb3211cb62a069125357f2ee8b263d
http://hdl.handle.net/20.500.12328/3633
http://hdl.handle.net/20.500.12328/3633
Autor:
Helena Muley, Karmele Valencia, Josefina Casas, Bea Moreno, Luis Botella, Fernando Lecanda, Rut Fadó, Núria Casals
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 946
Breast cancer (BC) is the most common malignancy in women worldwide. While the main systemic treatment option is anthracycline-containing chemotherapy, chemoresistance continues to be an obstacle to patient survival. Carnitine palmitoyltransferase 1C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1f5eeae8e30dbfb4a5a86836773753
https://ddd.uab.cat/record/270876
https://ddd.uab.cat/record/270876
Autor:
Esther Gratacòs-Batlle, Mireia Olivella, Nuria Sánchez-Fernández, Natalia Yefimenko, Federico Miguez-Cabello, Rut Fadó, Núria Casals, Xavier Gasull, Santiago Ambrosio, David Soto
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
In neurons, AMPA receptor (AMPAR) function depends essentially on their constituent components:the ion channel forming subunits and ion channel associated proteins. On the other hand, AMPAR trafficking is tightly regulated by a vast number of intrace
Externí odkaz:
https://doaj.org/article/a5cf60ebc0a74937914362a013464cea