Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Néstor de la Visitación"'
Autor:
Javier Moleón, Cristina González-Correa, Sofía Miñano, Iñaki Robles-Vera, Néstor de la Visitación, Antonio Manuel Barranco, Manuel Gómez-Guzmán, Manuel Sánchez, Pedro Riesco, Eduardo Guerra-Hernández, Marta Toral, Miguel Romero, Juan Duarte
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 106997- (2023)
Our objective was to investigate whether short-chain fatty acids (SCFAs), specifically acetate and butyrate, could prevent vascular dysfunction and elevated blood pressure (BP) in mice with systemic lupus erythematosus (SLE) induced by TLR7 activatio
Externí odkaz:
https://doaj.org/article/fd22df6950b54ca8ba9fa741ad646d45
Autor:
Javier Moleón, Cristina González-Correa, Iñaki Robles-Vera, Sofía Miñano, Néstor de la Visitación, Antonio Manuel Barranco, Natividad Martín-Morales, Francisco O’Valle, Laura Mayo-Martínez, Antonia García, Marta Toral, Rosario Jiménez, Miguel Romero, Juan Duarte
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTThis study is to investigate whether dietary fiber intake prevents vascular and renal damage in a genetic mouse model of systemic lupus erythematosus (SLE), and the contribution of gut microbiota in the protective effects. Female NZBWF1 (SLE)
Externí odkaz:
https://doaj.org/article/80f6f931713a4a0eae1385f63b15461c
Autor:
David M. Patrick, Néstor de la Visitación, Jaya Krishnan, Wei Chen, Michelle J. Ormseth, C. Michael Stein, Sean S. Davies, Venkataraman Amarnath, Leslie J. Crofford, Jonathan M. Williams, Shilin Zhao, Charles D. Smart, Sergey Dikalov, Anna Dikalova, Liang Xiao, Justin P. Van Beusecum, Mingfang Ao, Agnes B. Fogo, Annet Kirabo, David G. Harrison
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Externí odkaz:
https://doaj.org/article/ca2b2307570149e1b1825e689f0a9a8f
Autor:
Iñaki Robles-Vera, Néstor de la Visitación, Marta Toral, Manuel Sánchez, Manuel Gómez-Guzmán, Rosario Jiménez, Miguel Romero, Juan Duarte
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 135, Iss , Pp 111189- (2021)
Microbiota has a role in the host blood pressure (BP) regulation. The immunosuppressive drug mofetil mycophenolate (MMF) ameliorates hypertension. The present study analyzes whether MMF improves dysbiosis in a genetic model of hypertension. Twenty we
Externí odkaz:
https://doaj.org/article/3953db32ce3f4431b80216bbe5993d4d
Autor:
Iñaki Robles-Vera, Marta Toral, Néstor de la Visitación, Nazaret Aguilera-Sánchez, Juan Miguel Redondo, Juan Duarte
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Short-chain fatty acids (SCFAs) are among the main classes of bacterial metabolic products and are mainly synthesized in the colon through bacterial fermentation. Short-chain fatty acids, such as acetate, butyrate, and propionate, reduce endothelial
Externí odkaz:
https://doaj.org/article/a81eb00a5dd74598b17f3f21fb14cc4e
Autor:
Cristina González-Correa, Javier Moleón, Sofía Miñano, Néstor de la Visitación, Iñaki Robles-Vera, Manuel Gómez-Guzmán, Rosario Jiménez, Miguel Romero, Juan Duarte
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 84 (2021)
Plasma levels of trimethylamine N-oxide (TMAO) are elevated in lupus patients. We analyzed the implication of TMAO in autoimmunity and vascular dysfunction of the murine model of systemic lupus erythematosus (SLE) induced by the activation of the Tol
Externí odkaz:
https://doaj.org/article/4e24a41ac1a8492eafe6657be6484486
Autor:
Néstor de la Visitación, Iñaki Robles-Vera, Javier Moleón, Cristina González-Correa, Nazaret Aguilera-Sánchez, Marta Toral, Manuel Gómez-Guzmán, Manuel Sánchez, Rosario Jiménez, Natividad Martin-Morales, Francisco O’Valle, Miguel Romero, Juan Duarte
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1426 (2021)
Our group has investigated the involvement of gut microbiota in hypertension in a murine model of systemic lupus erythematosus induced by Toll-like receptor (TLR)-7 activation. Female BALB/c mice were randomly assigned to four experimental groups: an
Externí odkaz:
https://doaj.org/article/f3b983c20910496a82a96291dcca5851
Autor:
Marta Toral, Iñaki Robles-Vera, Néstor de la Visitación, Miguel Romero, Tao Yang, Manuel Sánchez, Manuel Gómez-Guzmán, Rosario Jiménez, Mohan K. Raizada, Juan Duarte
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Association between gut dysbiosis and neurogenic diseases, such as hypertension, has been described. The aim of this study was to investigate whether changes in the gut microbiota alter gut-brain interactions inducing changes in blood pressure (BP).
Externí odkaz:
https://doaj.org/article/b6c3d1d4f3a3432e99ca1fcaaae1e033
Autor:
Iñaki Robles-Vera, Néstor de la Visitación, Manuel Sánchez, Manuel Gómez-Guzmán, Rosario Jiménez, Javier Moleón, Cristina González-Correa, Miguel Romero, Tao Yang, Mohan K. Raizada, Marta Toral, Juan Duarte
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1199 (2020)
Microbiota is involved in the host blood pressure (BP) regulation. The immunosuppressive drug mofetil mycophenolate (MMF) ameliorates hypertension. The present study analyzed whether MMF improves dysbiosis in mineralocorticoid-induced hypertension. M
Externí odkaz:
https://doaj.org/article/722ad91a534242a58a0d611572c2e849
Autor:
Jaya Krishnan, Néstor de la Visitación, Elizabeth M. Hennen, Venkataraman Amarnath, David G. Harrison, David M. Patrick
Publikováno v:
Hypertension. 79:1644-1655
Background: IsoLGs (isolevuglandins) are electrophilic products of lipid peroxidation formed in the presence of reactive oxygen species. IsoLGs contribute to hypertension by an unknown mechanism. Studies have shown that reactive oxygen species produc